Genetic Technology (Precision Breeding) Bill

Lord Benyon Excerpts

2nd reading
Monday 21st November 2022 Lords Chamber

Moved by

[Lord Benyon]

That the Bill be now read a second time.

[The Minister of State, Department for Environment, Food and Rural Affairs (Lord Benyon) (Con)]

My Lords, it is a privilege to open the Second Reading of the Genetic Technology (Precision Breeding) Bill. I declare my interests as a farmer.

Science, research and development are at the heart of igniting the United Kingdom’s economic recovery, boosting productivity, creating new jobs and improving people’s quality of life. The United Kingdom is a world leader in genetics and genomics. With this Bill, we are supporting scientists to harness the huge potential locked within the DNA of plants and animals and will make sure that plants and animals developed using precision breeding are regulated proportionately to risk. We will also introduce a new science-based authorisation process for the food and feed produced from them and ensure that appropriate safeguards are put in place to regulate precision-bred organisms.

I am proud to present the exciting and vital opportunity that the Bill offers farming and the environment. It will give farmers options for greener, more resilient and more productive farming in the face of climate change and global challenges to world markets. Precision breeding has the potential to develop plants and animals that are more resilient to weather and resistant to disease and less reliant on chemicals such as pesticides and antibiotics.

This year we have seen England endure one of the hottest summers on record, leading to drought declarations in many parts of the country. Farmers have faced lower yields, higher fertiliser costs and challenging conditions for animal welfare. We do not have time to hesitate when it comes to ensuring that the right varieties and breeds are available to farmers to help them face volatile markets and a changing climate.

I will give noble Lords an example of how the Bill could help increase food production from a crop on which 2.5 billion people are dependent. At the John Innes Centre in Norwich, leading researchers have used precision-breeding techniques to identify a key gene in wheat that can improve traits such as heat resilience while maintaining high yield. This development could help address issues of rising temperatures not only at home but abroad.

The genetic technology Bill will create a new proportionate regulatory environment that will encourage innovation to help us adapt to the impacts of climate change. Many would say that this is long overdue. It is not an overstatement to say that precision-breeding technologies such as gene editing have the potential to revolutionise farming. Science has moved on from where we were 30 years ago, and this should be reflected in our legislation so that we can harness the benefits of these technologies.

I know that some noble Lords may have concerns regarding the safety of precision breeding. On that front, I hope to provide reassurance. For thousands of years, we have been breeding crops and animals to domesticate them and select desirable characteristics. Using the potential of animal and plant DNA in breeding programmes has resulted in safe and trusted products. Precision breeding is the latest in this line of breeding techniques which utilise this same resource. Under the Bill, an organism will be considered precision-bred only if it could have occurred through traditional or natural processes. Therefore, precision breeding allows us to introduce beneficial characteristics that could have occurred through traditional breeding, but much more precisely and efficiently.

In putting forward the Bill, we are choosing to follow the science. The scientific advice from independent scientific experts and our expert Advisory Committee on Releases to the Environment, or ACRE as I shall refer to it, is that organisms produced through precision-breeding technologies pose no greater threat to the environment and health than their traditionally bred counterparts.

The Bill sets out four key policy objectives which would enable the proportionate and science-based regulation of precision-bred organisms, while still making provision for appropriate safeguards for precision-bred plants, animals and the food and feed derived from them. The first objective is to remove plants and animals produced through precision breeding from the regulatory requirements governing the environmental release and marketing of genetically modified organisms, also known as GMOs. The key difference between precision breeding and genetic modification is that genetic modification produces organisms containing genes from a sexually incompatible species that could not occur naturally or by traditional breeding. The current GMO legislation will continue to govern these organisms.

Secondly, the Bill will introduce two notification systems: one for precision-bred plants and animals used in research trials, and a second for the marketing of precision-bred plants and animals. The information collected from these notification systems will be available on a public register on GOV.UK, which I hope will give noble Lords confidence in the transparency that the Bill provides.

The third objective will be to establish a proportionate regulatory system for the marketing of precision-bred animals to ensure that animal welfare is safeguarded. I understand that some of your Lordships may have some concerns regarding the inclusion of animals in the Bill. The Government are committed to maintaining our already high standards in animal welfare. That is why we are planning to take a step-by-step approach, facilitating the commercial use of precision-breeding technologies in relation to plants first, followed by animals later. We will work closely with industry, animal welfare NGOs, scientific advisers and other stakeholders to design the next steps.

To ensure that animal health and welfare are safeguarded, under the Bill anyone wishing to place a precision-bred vertebrate animal on the market will have to submit an animal welfare declaration, which will be assessed by an animal welfare advisory body. These measures are designed to safeguard animal welfare and ensure that the health and welfare of relevant animals will not be adversely affected by any trait that results from precision breeding.

I hope noble Lords are reassured that the measures in the Bill will not only safeguard animal welfare standards but have the potential to improve them. For instance, in research by Imperial College London, the Pirbright Institute and the Roslin Institute, we have seen the potential to use gene editing to produce chickens that are resistant to avian influenza—a disease that noble Lords will know is currently having a devastating effect on wild birds and poultry farming in this country.

The final policy objective will be to enable the establishment of a new science-based pre-market authorisation process for food and feed products developed using precision-bred organisms. The Food Standards Agency will design a new framework that is more proportionate to the risk profile of precision-bred food and feed products. This authorisation process will build on five key principles: safety, transparency, proportionality, traceability and building consumer confidence.

The Bill has the potential not only to unlock benefits for the economy, as the size of the global market for technologies such as gene editing is predicted to rise to over £7 billion by 2026, but to unlock benefits for farming and to address the impacts of climate change and to reduce food waste. Tropic Biosciences is an example of the innovative, smaller bioscience research companies that the Bill will benefit. It has recently developed a non-browning banana using precision-breeding techniques. Given the fruit’s high perishability, this innovation has the potential to reduce waste, which helps both the environment and consumers. It is exciting to think that the Bill will support investment in both Britain’s leading research institutions and SMEs such as Tropic. As we move to align with our international partners and harness the benefits of these technologies, we are enabling the development of foods enjoyed at home and abroad.

I am looking forward to what I am sure will be an enlightening debate. I beg that the Bill be read a second time.

--- Later in debate ---

[Lord Benyon (Con)]

My Lords, I thank noble Lords for their insightful and engaging contributions to today’s debate. It undoubtedly shows this House at its best when it draws together scientists, former Ministers, farmers, leaders of the veterinary profession and many other insightful contributions on this very important legislation.

I broke a self-denying ordinance in my opening remarks when I said that we were going to follow the science. I always promised myself that I would never use those terms again, because after many years in the department in which I now serve, I have been given conflicting scientific advice on so many issues. Others who have been Ministers there will know that, if you are a layman, as I am, you can sometimes find scientific advice prayed in aid by polar opposites. I find a much more united scientific body of opinion in support of this legislation than on anything else I have done, which is why I broke my self-denying ordinance.

Others have spoken of scars on their backs. I really appreciate the insight given by the noble Lord, Lord Krebs, the noble Baroness, Lady Hayman, and others into how the arguments on this issue were in some ways traduced—that is perhaps not too strong a word—by others to create the impossibility of having rational debate. What we are trying to do here is bring this down to a proportionate measure, grasp the benefits of this technology and regulate out the disadvantages and malign effects. If we just concentrate on this and are too cautious, we will lose all the precious advantages that noble Lords have spoken about today with such eloquence.

It is clear to me that the exciting potential of precision breeding will of course ignite passions about how we should grow, buy and eat food, as well as about how we should care for our crops, the animals on our farms, biodiversity and the planet. This Bill complements the great work that Defra has been doing in these areas. I assure noble Lords that I know that precision breeding is not a silver bullet—the very words used by some—but it will be another tool in our toolkit as we adapt to climate change and a turbulent global environment.

Jonathan Swift seems to have come in for quotation, so I will give noble Lords another quote. He said:

“Proper words in proper places make the true definition of style.”


With this legislation, we are trying to use proper words in proper places. I am happy to debate this tonight—and, of course, in Committee and at other stages of the Bill—to make sure that we are getting that right. I understand that views may differ on some of the finer details of this legislation, but I will take this opportunity to reassure noble Lords on some of the concerns raised in this debate.

I start by paying tribute to my noble friend Lord Roborough for his excellent maiden speech. He brings to this House wide experience: that nexus of an understanding of agriculture, finance and natural capital can be incredibly powerful in our deliberations. What he said about climate change, echoing the point made by the noble Lord, Lord Cameron, and others, reminded me of an incredibly moving conversation that I had at COP with a Minister from the Maldives. She was talking about the salination of the atolls that make up that low-lying country. The point has been made about trying to create opportunities in countries where, for example, salination is becoming a problem, such as by making species of crops that can be resistant to that, thus giving us an opportunity to help some of the most vulnerable people in this world.

People like me sit at the foothills of understanding of this issue when people such as the noble Lord, Lord Winston, speak. That was brought home to me in an analogy from the chairman of the Food Standards Agency, which I, as a layman, found really helpful. What we are talking about here is a paragraph in a book. We are taking out one or two words from that paragraph and replacing them with other words from the same book. That is totally different from what we were being accused of 20 years ago: taking out the entire paragraph and putting in a paragraph from another book. I know that that probably does not stack up when it comes to exact scientific examples—the noble Lord, Lord Winston, is shaking his head, which makes me think that I got that one wrong—but the point is that we need to explain this and communicate it to a wider group of people; the noble Baroness, Lady Parminter, is absolutely right to try to do that. I will come later to some of the other points that the noble Lord, Lord Winston, made.

The noble Lord, Lord Krebs, made an incredibly powerful speech. He referred to Jane Langdale; I am going to see her when I visit her laboratory to really immerse myself in the details of this. I am grateful to the noble Lord for making that point, and the point about the consumer benefits that will undoubtedly flow from this.

My noble friend Lord Jopling gave an interesting historical perspective on this. He referred to a number of issues where there can be enormous benefits; I will come on to the animal welfare possibilities. His point about the nitrogen-fixing nodules on wheat—indeed, many of things he talked about—may not be within the exact confines of this legislation, but undoubtedly he spoke about there being great possibilities with the technology within the confines of the Bill.

The noble Baroness, Lady Jones, wants me to delay the Bill. I hope that she listens to the scientists she works with at Rothamsted; as my noble friend Lord Lilley pointed out, they are in favour of this Bill. We can kick this can down the road if we so wish, but we will miss out on an opportunity about which many noble Lords spoke so eloquently. However, like other noble Lords, the noble Baroness was absolutely right to point out that this should not be a substitute for bad husbandry. We should not create a pathway towards types of farming activity that we are moving away from. We have some of the highest animal welfare standards in the world; that is something that we should be proud of and where we should continue to push boundaries. I will come on to talk about that in a minute.

Many noble Lords spoke on issues which I will come to in a moment, but in response to the concerns of the noble Baroness, Lady Bennett, regarding allergens: no, that will not be the case. The Food Standards Agency has a very clear remit and success in protecting people from allergens. All the transparency issues relating to labelling which people may be concerned about will exist and the current food safety legislation will still apply regarding the chance of an allergen finding its way into a foodstuff. What I do agree with the noble Baroness about is an ecosystems approach to food production. This was echoed by my noble friend Lord Caithness. Britain has signed up to, and will be consistent with, the Cartagena protocol, which she may not be aware of. It underlies what we are talking about.

My noble friend Lord Lilley apologises for no longer being here. He spoke about the precautionary principle. I am fully signed up to this being front and centre in the Environment Act and many other areas. I am sad enough a person to have read the EU guidance on its use and implementation. Sometimes I must remind parts of Defra and its agencies what the precautionary principle is and what it is not. He is right to point it out. The analogy of the chicken was well made by the noble Baroness, Lady Hayman.

A number of noble Lords talked about polling and public opinion on this. Of course, it depends on the question that you ask. If you ask people a question in a way that makes them feel unsafe, they will give you a negative answer, but if you ask it in a positive way, perhaps reflecting some of the exciting possibilities in terms of vulnerable people around the world, Britain’s ability to grasp this technology and be a world leader, and all the other things, you get a different answer. I have been a politician long enough to respect that perceptions are reality in the game that we live within. We perhaps need to do more to get the message across.

I pay tribute to the noble Lord, Lord Cameron, the midwife of the Bill, and his appeal for the urgency of it. That is why kicking the can down the road is not an option. There is a requirement to tackle this now. The noble Lord, Lord Rooker, is a former Minister for whom I have great respect. I will talk about virus yellows in sugar beet as a possibility for this technology. Often, we have fearsome debates in this Chamber about derogations for the use of neonicotinoids on sugar beet. So far, we have not had to use them, but if we can breed out virus yellows and continue to produce sugar in this country, that is good for so many different reasons.

The noble Lord, Lord Winston, was one of several noble Lords to raise the concern about the use of the words “precision breeding”. As the changes that we are considering are similar to natural breeding, it is not misleading to use “breeding” within the definition of a qualifying plant or animal. Meanwhile, “precision” reflects the specific, targeted nature of changes which can be introduced by such technologies and which we are considering in the Bill. By not naming the products of such techniques after the technology used to produce them, we futureproof the Bill against developments in this area. For example, genome editing is currently the most popular technology that breeders are using to make the kinds of changes that we are considering in the Bill. However, this may change, so naming qualifying plants and animals “gene-edited organisms” or similar would not be appropriate.

Whether this is a move to GMO by stealth has also been raised. Precision breeding is different from genetic modification, where modern techniques are used to insert genes from one unrelated species to another, for a desired trait or beneficial outcome. Precision-bred plants and animals will have only genetic changes that could occur through traditional breeding.

[Lord Winston (Lab)]

I apologise for interrupting at this late stage of the debate, which has been really thoughtful and helpful.

The Minister might want to consider the difference between DNA that is naturally produced and is what the Bill is talking about and DNA that is produced in a gene sequencer, completely chemically. An issue here is that there is not really any difference at all. We must consider that very carefully.

Do not forget, too, in spite of your spelling, that if three base pairs are missing, for example, you end up with cystic fibrosis, which is a killer. One base pair will do with many diseases, so there is a real problem with these definitions. I hope the Minister will forgive me for interrupting; I do not expect an answer, but it is something we will need to consider during the next stage of the Bill.

[Lord Benyon (Con)]

I am not going to debate with the noble Lord, because he knows much more about this than me, and I know that I would sound even weaker if I just read out a line that has been written. But I value his contribution and I hope to tease out some of these matters as we go through the remaining stages of the Bill.

In response to a point made by the noble Lord, Lord Krebs—I hope I have got this right—in some cases, transgenic organisms will be used as an intermediate step in the development of precision-bred organisms. However, for the end product to be classed as a precision-bred organism, genomic features that could not have occurred naturally or resulted from traditional breeding must be removed from these organisms. For example, this would include removing CRISPR-Cas9 genes from gene-edited organisms.

DNA fragments from sexually incompatible species are naturally present in many organisms. This is in line with what could occur naturally—and I hope the noble Lord, Lord Winston, is on board on this. Therefore, we are allowing for foreign DNA to be present in precision-bred organisms only so long as this DNA does not serve any function and is within the range achievable through natural processes.

The noble Lord, Lord Krebs, also asked why companion animals are in the Bill, and a number of other noble Lords referred to this. Independent scientific experts advise that precision-bred organisms pose no greater risk to the environment or health than traditionally bred organisms. This applies to companion animals, as well as farmed animals. We are aware of precision breeding research that is already taking place on animals that could lead to positive welfare outcomes, such as increased disease resistance. Although there is less research taking place on companion animals, there is early research on the use of precision breeding—for example, in improving hip dysplasia in dogs. We do not want to restrict the potential benefits that can be achieved to improve the health and welfare of these species. That is why they are included in this Bill. I would say that that is not a priority, but it is definitely important that we future-proof the Bill.

We are not aware of the specific project to which my noble friend Lord Jopling referred and I would be interested to hear about it. A project that may be relevant was recently authorised by the Secretary of State for a field trial of GM and gene-edited barley. This is related to the concept about which my noble friend spoke. It is being undertaken by the Cambridge Crop Science Centre and is investigating the potential to increase yields by altering the interaction between the plant’s roots and the soil micro-organisms with which they are associated. We are not aware that any research group has yet succeeded in developing wheat plants in the laboratory that can fix nitrogen like legumes can.

I agree with the noble Lord, Lord Trees, that disease is a welfare issue. I cannot put it better than he did. The Government are committed to maintaining our already high standards in animal welfare, and we want to improve and build on that record. I assure noble Lords that this Bill will not lower the standards set by current legislation. He refers to zoonotic diseases and there is a human health element to this. This Government are very much signed up to the “one health” concept, so there is a wider benefit from this.

I will address the questions about why we are including provisions for animals in this Bill. Precision-breeding technologies such as gene editing have the potential to improve the health and welfare of animals, and improve the sustainability and resilience of farming systems. Such technologies can enable new traits to be developed more precisely and more efficiently than traditional breeding. The noble Lord, Lord Winston, made a really interesting point about genetic diversity. I cannot remember what percentage it is, but many of our dairy cows are descended from a very small number of bulls. It could be that in the future, because of recent trends, something occurs that endangers the health of many of them—I am not saying the whole dairy herd—because of their genetic uniformity. We want to be able to correct circumstances such as those as quickly as possible, and this legislation should allow us to de-risk that situation.

Research in farmed animals is already leading to the development of animals that have increased resistance against some devastating diseases. A number of noble Lords have spoken about the great organisations we have in this country: for example, the Roslin Institute and others such as Genus have developed gene-edited pigs with resistance to porcine reproductive and respiratory syndrome, or PRRS. It is a disease that causes mortality and major welfare issues in pig populations globally. This has been referred to by a number of noble Lords.

Whilst there is great potential for increasing innovation, we recognise that there is a need to safeguard animal welfare in the new regulatory framework. That is why, as I have already said, we are taking a step-by-step approach, facilitating use of precision-breeding technologies in relation to plants first followed by animals later. The measures in the Bill are designed to ensure that the health and welfare of relevant animals will not be adversely affected by any trait that results from precision breeding. To provide some further reassurance, I would also like to take this opportunity to expand on what the system for protecting animal welfare will look like. I am mindful of the time, but I will be as brief as I can.

Before marketing a precision-bred vertebrate animal, developers will need to provide assurances to confirm that the health and welfare of the animal will not be adversely affected by any trait resulting from precision breeding. This will be in the form of an animal welfare declaration and accompanying evidence. The Secretary of State will need to be satisfied with the declaration before issuing a precision-bred animal marketing authorisation, after which point a precision-bred animal can be marketed. This process will also involve an independent scientific assessment of the declaration by a welfare advisory body. We have also commissioned a research project to help us design the animal welfare declaration process and will work closely with a wide range of stakeholders as this work progresses.

I hope my words, the ongoing research project and engagement on these issues will provide noble Lords with some assurance that we fully acknowledge the importance of animal welfare, and we will continue to protect the high standards that we are proud to uphold.

I turn to labelling and the issues raised by the noble Lord, Lord Rooker, and others. The Bill will provide the Food Standards Agency with the ability, through regulations to be made by the Secretary of State, to introduce a new proportionate and science-based food and feed authorisation process. This will include a pre-market risk assessment for food and feed products developed using precision-bred organisms. The FSA’s role is not being diminished but enhanced—we could not be doing this without it—and it has produced some really interesting work in support of what we are doing.

I will address the points on traceability made by the noble Lord, Lord Rooker, and others. To ensure transparency, there will also be a public register of authorised precision-bred organisms for food and feed uses. This will provide consumers, industry and enforcement authorities with information on the precision-bred organism authorisation date, product, developer, characteristics, and food or feed uses. This will give clarity on food business operators involved in the supply of precision-bred organism food and feed products and enable traceability back to source.

A number of noble Lords have raised concerns about the delegated powers. Let me assure them that this is not a skeleton Bill. The powers supplement the principal policy measures which are set out on the face of the Bill and are quite specific and technical in how they are intended to be used. Your Lordships will know that delegated powers serve a valuable purpose, and it is always important to assess them in context. Simply counting up the number of powers in a given Bill is not necessarily meaningful. There are Henry VIII powers, which I know that your Lordships are quite rightly keen to scrutinise. They exist in Clause1(8), Clause 10(2) and Clause 42(1). I am sure that we will discuss those if noble Lords give this Bill the boost that it needs to get into Committee. I will hopefully be able to satisfy your Lordships about the need for them and the proportionality with which they have been put in the Bill.

I am coming to the end of my remarks, but I must address the points made by the noble Baroness, Lady Parminter, the noble Earls, Lord Caithness and Lord Devon, and the noble Lord, Lord Carrington, about trade. They quite rightly want to ensure that trade will not be negatively affected by this Bill. The international regulatory regime for precision-bred products is rapidly evolving. Many countries, as has already been said, have already amended their equivalent regulations, including the United States, Canada, Japan, and Argentina. Our proposed approach would help facilitate greater trade with those countries that have already adopted a similar approach to the regulation of precision-bred organisms.

With regard to the EU, this summer it conducted a consultation on legislation for plants produced by certain new genomic techniques, which is the term it uses for techniques such as gene editing. Some 80% of the respondents agreed that the existing GMO legislation was not adequate for plants, and more than 65% mentioned negative consequences if the regulations were not amended. These consequences included the loss of tools to tackle climate change, to develop more resilient crop varieties and to reduce the use of phytosanitary products. In response to the point made by my noble friend Lord Lansley, we will continue to monitor the position of the EU on precision-bred products and on UK/EU trade implications for products developed using precision breeding.

As things stand, the noble Baroness, Lady Parminter, is absolutely right. If we pass this Bill, some material produced through precision breeding and sold into Europe would be treated as a GMO there, but they are moving fast and we want to make sure that we are too. The global market value for gene editing is estimated at £2.7 billion in 2020 and expected to rise to more than £7 billion by 2026. I therefore ask noble Lords to consider the impacts and missed opportunity that would be caused by not supporting this important transition and the scientific basis for it.

Concerns have been raised about the impact assessment. I reassure noble Lords that this red rating is not a reflection on the quality or the ambition of the Bill. The Government are committed to proportionate, science-based regulations and have carefully considered all views and evidence in establishing our approach. The main criticism of the RPC is that the description of the policy differed between the initial review notice and the final submission. It felt that the impact assessment had not adequately accounted for the potential impacts arising from this policy change.

We are clear that at no point has the policy changed. The final submission had small changes in terminology such as changing the title of the Bill from “gene editing” to “precision breeding”. In our engagement and evidence-gathering, researchers and developers were made aware of the policy intention, and that the name had not been finalised, and so our expectation is that the change of the name to precision breeding will be of no impact on researchers or developers.

In response to the RPC’s comments, work is under way to gather further evidence from stakeholders and additional consumer insight data to provide more detail on the impacts to businesses and to bolster the cost-benefit analysis. We are also seeking to provide information to give more clarity on the policy intention, the Bill’s objectives and the options appraisal. Defra is working closely with the RPC and will submit an enactment impact assessment which will address its comments, and this will reflect any amendments made to the Bill as it progresses through Parliament.

On the point made by the noble Baroness, Lady Jones, about pausing the Bill, the policy has not changed. His Majesty’s Government are absolutely committed to supporting proportionate, science-based regulation. Our engagement and evidence-gathering will, I hope, address her concerns.

We recognise that the devolved Administrations’ positions regarding this legislation differ. My department has had very good conversations with a number of people. I have meetings next week with the devolved Administration in Wales and we will be talking to the Scottish Government as well. The noble Earl, Lord Stair, raised the point that this is a devolved issue. The Scottish Government have declined to join the Bill but the Welsh Government remain open to discussions via the common frameworks. We also engage with leading research organisations: with the Roslin Institute and the James Hutton Institute in Scotland, and with Aberystwyth University and Bangor University in Wales. These are world-leading organisations and they are calling for this kind of legislation. The electoral dynamic will, of course, differ in different parts of these islands and we want to make sure that we are talking to and working with the devolved Governments, and that we come to the right conclusions. I hope that we can persuade them to come along with us.

The noble Earl, Lord Devon, talked about the IP implications and whether precision-bred crops and organisms can be patented. The patent system exists to encourage inventions by offering time-limited exclusive rights in exchange for making the invention public, allowing others to further develop it. I am preaching to the choir; he is, of course, an expert on this. Patent rights are available in the UK in the area of gene editing, including plants and animals modified by such techniques. A number of patent applications have been filed and patents granted that relate to the genome-editing tool CRISPR.

The noble Earl and others also raised issues relating to the World Trade Organization. In 2018, a joint statement issued to the World Trade Organization signed by 13 countries stated that Governments should

“avoid arbitrary and unjustifiable distinctions”

between those crops developed through precision breeding and those developed through conventional breeding. The signatories included Canada, Argentina, Australia, Brazil and the USA. We are moving in that direction.

I have not had time to answer everyone’s points, even though I have been rather lengthy in my reply. It is important that we have open conversations. This has been an incredibly fascinating debate. I am encouraged by the level of support for the Bill. I hope we can progress it through the House. I beg to move.

Bill read a second time and committed to a Grand Committee.

Genetic Technology (Precision Breeding) Bill

Lord Benyon Excerpts

Committee stage
Monday 12th December 2022 Lords Chamber

[Baroness Hayman of Ullock (Lab)]

I thank the noble Lord, Lord Krebs, for his very important point. We need to think about where we want to go with this and how we want those regulations to come in as we go through the Bill. I am sure that we will be having some very interesting debates on that as we move forward. Clearly, the whole purpose of the Bill is about deregulating the law on gene editing so that we can actually move forward beyond the traditional breeding processes.

The purpose of this group is to look at the definitions as to how we move forward; what we mean by that; and whether the Bill has the right definitions in it. The noble Baroness, Lady McIntosh of Pickering, talked about unintended outcomes, for example. The interesting thing for me is whether “precision breeding” is the right terminology. Why have the Government picked that terminology? That is something that a lot of noble Lords raised on Second Reading, and again now.

The noble Baroness, Lady McIntosh, also talked about the EU. One of the things that I have noted is that the EU has quite a different term. I am not aware that the European Union is using the term “precision breeding”, but it is looking at “new genetic techniques”. How does what we are doing in this regulation fit in with what the European Union is doing? We will be talking about trade later on but, clearly, it is going to be very important that it all fits together and works together in the long term. It is going to be very interesting to look at how we develop as we go on.

A lot of the definitions are quite vague as well. It would be helpful if the Minister could, perhaps, explain some of the definitions in Clause 1. For example, in Clause 1(1), the actual definition of “precision bred organism” is very, very broad. Is it deliberately broad? Is it trying to capture something in particular? My noble friend Lord Winston talked about traditional processes and natural transformation, as well as referring to “stable”. Understanding what these actually mean and their implications for the Bill going forward are important.

Amendment 86, from the noble Baroness, Lady Bennett of Manor Castle, again refers to the title, coming back to what we have just been talking about. She also has Amendment 11 on exogenous genetic materials. There has been some work done by Defra to shed some light on this. The consultation, for example, that was carried out last year, states that

“this proposal does not apply to organisms which introduce genetic material from other species.”

However, that distinction, as we have heard, is not in the Bill. Does it need to be in the Bill?

It is not stated anywhere that precision breeding technologies are technologies that edit a single organism. I refer to Clause 1(7), which refers to

“somatic hybridisation or cell fusion of plant cells of organisms which are capable of exchanging genetic material”.

What does that mean? Does that open the door to transgenic exchange, for example? Some of it is quite weak on definitions, and some of the definitions could be stretched to include pretty much anything—so I do think that some kind of clarification would be very helpful.

The chief scientific adviser to Defra, Professor Henderson, giving evidence to the Commons Select Committee, said that the Bill was designed not to allow exogenous material. He also said, however, that this was something of a grey area. Particularly in the light of what the noble Lord, Lord Krebs, said—and he has a far greater understanding of this than I do—it is very important to get clarification on this area before we move further on into the detail of the debate.

[The Minister of State, Department for Environment, Food and Rural Affairs (Lord Benyon) (Con)]

My Lords, I am very grateful for this interesting debate on this first section. I will start with, I hope, a note of humility: I understand that I am in the presence of people who have proved, in the introductions by the noble Lords, Lord Winston and Lord Krebs, and others, that I sit at the foothills of knowledge compared with them. The noble Baroness, Lady Bennett, quoted Descartes—I think he said, “All I know is that I know nothing”. I hope I know a bit more than that, although my learning curve has been very steep. I am grateful to officials at Defra and others who have helped me through this process.

I am aware that the term “precision breeding” has been controversial in some quarters, although well received in others. I thank noble Lords for this opportunity to explain why we have adopted it. The noble Lord, Lord Winston, suggested “directed bred” as an alternative term to “precision bred”, whereas, on this point, the noble Baroness, Lady Bennett, suggested “genome editing” to replace “precision breeding”. Concerns have been raised about using the term “precision bred” to describe these organisms, because they can result in off-target changes to the organism’s DNA. Although off-target changes can occur using precision breeding technologies, the advice we have received from our Advisory Committee on Releases to the Environment—ACRE—in relation to precision-bred plants is that off-target changes are significantly rarer than those produced during the course of conventional methods of plant breeding. This is also the view of the European Food Safety Authority, which advises the EU Commission.

On animals, ACRE concluded in its advice published in September last year that there is good evidence to suggest that the use of techniques such as CRISPR-Cas9 in animals does not result in a greater number of off-target changes than the background rate for natural mutations—the noble Lord, Lord Krebs, referred to this. Indeed, many recent gene-editing studies on animals have reported no incidences of off-target changes when using CRISPR-Cas9. Therefore, although off-target changes may occur using these technologies, the scientific advice is that they are more precise than traditional breeding, both in terms of making targeted changes to the DNA of a plant or animal and in terms of the number of off-target changes they cause.

In her amendment, the noble Baroness, Lady Bennett, used the term “genome editing” instead of “precision breeding”. The class of plants and animals we intend the term to cover will include some gene-edited organisms. However, it will not cover all gene-edited organisms; it will not include plants and animals that contain genetic features produced by modern biotechnology that could not have occurred naturally or by traditional processes. For example, plants or animals developed using gene-editing techniques to contain engineered gene drives would not be included in this new class of organism; they will still be regulated as GMOs. In addition, there are techniques of modern biotechnology other than gene editing that could produce plants and animals in this new class—for example, cisgenesis. It is important to note that the EU is also considering cisgenic, as well as gene-edited, plants in its plans for regulatory reform.

We considered using the term “gene edited” in the Bill but, for the reasons I have explained, we concluded that this would be more misleading and confusing. The purpose of the Bill is to more closely align the regulation of this class of animals and plants with those produced by traditional breeding, recognising that the genetic changes they contain will have arisen in a more targeted and precise manner.

The noble Lord, Lord Winston, makes a very good point about the very important need to engage the public more on this case. The Government have tried very hard to do this, and the Food Standards Agency and wider organisations are doing some very good work. There is a big social science job to do to get the message out about what we are talking about—and, perhaps as importantly, what we are not—and the wider benefits, which we will come to in this and other clauses, about how we can improve the life of us here on this planet, protect animal health and make us more resistant to such factors as climate change. These are factors that we need to hold in our minds as we rightly debate this important Bill, line by line.

Amendment 10 would, in effect, remove the requirement that every feature of an organism’s genome must have been capable of resulting from traditional processes or natural transformation in order for the organism to qualify as precision bred. I understand that the noble Lord’s intention in tabling this amendment was to explore the meanings of the concepts of “traditional processes” and “natural transformation” that are used in this Bill. I hope to address his concerns around the terminology that we have used in this Bill and why it is appropriate. I will begin by defining what we mean by “traditional processes” and “natural transformation”.

For the purposes of this Bill, traditional processes refer to a number of methods listed in Clause 1(7). The noble Baroness, Lady Hayman, also referred to these. They are well known conventional breeding methods, some of which have been utilised for over 10,000 years, and therefore have a long history of safe use. The methods outlined in Clause 1(7) were not chosen to represent an exhaustive list of traditional breeding processes. Instead, they were chosen because they represent the full range of genetic changes known to occur naturally between sexually compatible plants and animals.

Scientific advice is that genetic changes that could have been achieved through traditional processes, as outlined, do not pose a greater risk as a result of being introduced by modern biotechnology. This is why we have included

“could have resulted from traditional processes”

as a criterion for obtaining “precision bred” status.

“Natural transformation” refers to the process by which DNA from a sexually incompatible organism may be inserted into an organism. In plants and animals, this is almost always the result of infection with a bacterium or virus. Often, the fragments of genetic material left behind after infection no longer serve a purpose or function. The material is non-functional and does not affect the physical characteristics, also referred to as the phenotype, of the plant or animal.

The effect of Clause 1(2)(c)(ii) and Clause 1(6) taken together is to ensure that, for the purposes of this Bill, DNA from a sexually incompatible species which is similar to that which occurs through natural transformation is allowed in a precision-bred organism. This is so long as it does not affect the physical characteristics of the precision-bred organism. This is supported by scientific advice that genetic features produced through modern biotechnology but which could have arisen in nature do not pose a risk as a result of the method of production.

DNA from a sexually incompatible species is critical in the intermediate stages of development of many precision-bred plants and animals. They enable the subsequent precise genetic changes to be made to these organisms. For example, CRISPR-Cas9 often involves insertion of the Cas9 editing machinery to enable the intended precise genetic edits. The Cas9 gene would need to be removed for the resulting plant or animal to be classed as precision bred. Clause 1(6) comes into play where, in some cases, small non-functional fragments of DNA from the Cas9 gene may be left behind. This would be allowed, provided the genetic changes created could have been introduced through natural transformation.

Taken together, the terms “traditional processes” and “natural transformation” ensure that precision-bred organisms are able to contain, in principle, changes that could develop in nature. It is this characteristic that makes precision-bred organisms and GMOs fundamentally different, and we believe that regulating them as such is a proportionate response to the growing body of scientific evidence supporting the safe use of precision-bred organisms.

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[Baroness Bennett of Manor Castle (GP)]

The noble Baroness, Lady Hayman, raised the issue of international compatibility of terminology. I am sure the Minister is aware that the International Organization for Standardization, more commonly known as ISO—and many noble Lords are familiar with ISO numbers applied to all sorts of technical and practical procedures—earlier this year produced a genome-editing vocabulary. It provides a list of internationally agreed terms that will

“improve confidence in and clarity of scientific communication, data reporting and data interpretation in the genome editing field.”

There is no mention of precision breeding in that internationally agreed ISO dictionary of terminology. Picking up the point from the noble Baroness, Lady Hayman: would it not be better if we used internationally acknowledged terminology?

[Lord Benyon (Con)]

The amount of time we spent in the department working with real experts in this field to get the terminology right means that I hope we can persuade other countries to adopt our definitions. I know that I am not going to find total agreement on this legislation with the noble Baroness, but I can try. As I explained at some length—and I apologise to noble Lords, but I think this is a really important part of this Bill—we have arrived at this definition in a coherent way. Of course, we are constantly looking at how other countries are doing this. We do not want to be left behind, but we want to keep this safe; we want to see what is happening in the EU, but we want to make sure we are giving our scientists and our businesses the right guidelines around which to develop a really exciting new area of technology.

[Lord Winston (Lab)]

I am very grateful to the Minister for his consideration of what I think are difficult areas in this Bill, which I think remain—we have not solved the problem yet. One of the things I really loathe in Committee is people who move an amendment then take a very long time making a long speech, which bores everybody because they have already heard it, but I feel I have to address a few points specifically. I will not do it again later in this Bill. I think I have views on every single amendment, but I will be careful not to mention them.

The noble Baroness, Lady McIntosh of Pickering, mentioned Dolly the sheep. I think Dolly the sheep is a particularly interesting issue, because one thing which will not have escaped your Lordships’ attention is that Dolly the sheep had exactly the same DNA as wherever else she was cloned. Yet animals with the same DNA do not always express the same genes. For example, identical twins in humans are often quite different in many subtle ways, including their fingertips, brain functions, thought processes and so on.

We have to accept that there are many characteristics which are not necessarily demanded, essentially, by the DNA itself but by other things as well. In particular, one of the things we have not yet discussed is the problem of epigenetics; it does come into the Bill. We know that genes can express in different ways under different environmental conditions. That expression can be altered from the very beginning of conception—that is what we are talking about here—which could be, for example, in vitro fertilisation. Of course, that is mentioned in the Bill.

One of the concerns I have about IVF, having been involved with it since its very beginning, is that we still have no long-term follow up on what it means in terms of epigenetics—that is, how genes will express in the future. There are many examples where the progeny of a species—for example, a mouse—may show complete changes with regard to obesity, for instance, due to an insult four generations earlier. One has to accept that these changes occur very early; the mothers are fed with fats at the very earliest stages of pregnancy, and four generations later, we see a sex-determined link with obesity in the progeny. These sorts of issues are not teased out here.

Clearly, a great deal of doubt is encompassed in the Bill and in the science of it. As the noble Lord rightly said, we must all have a degree of humility in trying to work out what is best. He and I, and I think most people in this Chamber, would agree that we are mostly concerned about one thing: the environment. We are concerned about climate change and how we might adversely affect our environment. As we will come to later with the release of organisms, one thing that is very clear is that sometimes in the past—with natural causes—organisms have been released into the environment. We can think of the hornet in Britain, the Bufo toad in Australia, or the fungus which causes elm disease in England. Those things have all been produced by simply being involved in our environment, with colossal difficulties. Of course, we do not ultimately know whether this is a problem with modified organisms.

There is one thing which is not discussed here but which we need to consider. What we have forgotten, partly, is evolution. We are trying to evolve a species in one step, and that is a difficulty. If you take the human species, since Homo sapiens was first in east Africa 100,000 years ago, there have probably been about 5,000 families of humans—that is all. We have not evolved very much; the human brain remains very much the same. It takes a very long time for it to change even small amounts. What we are doing here is expecting rapid change for the benefit of ourselves and, we hope, of the planet too, but the problem is that we are dealing with an environment that is constantly balanced and balancing. We are at risk of damaging that balance with so many things that we do, and I regret to say that this is one of the reasons we have to be very careful when we come at the end of the discussion to the problem of balance and, therefore, how we release these organisms into the environment and control that. That is why the Bill is so important.

Without any further ado—I have already spoken for too long—I simply ask permission to withdraw my amendment.

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[Lord Benyon (Con)]

My Lords, I am grateful to the noble Baroness, Lady Jones of Whitchurch, for reminding me that I have not referred noble Lords to my entry in the register or stated that I have farming interests. I thank her for being on the board of Rothamsted, one of the great institutions of this country. Many of the scientists there have been enormously helpful to us in the development of this legislation, and I am grateful to them for that.

I thank the noble Baroness for Amendment 2. The focus of our discussion has been on crop plants, but there is potential for precision breeding to be used in the breeding of other plant species, such as in forestry and ornamentals. I entirely agree with that. There would have to be a market for them, and I do not think they would be a priority for plant breeders in ornamentals, but there are huge possibilities for this in areas such as forestry.

The noble Baroness, Lady Wilcox, who I welcome to her post in the team, mentioned ash dieback. She is entirely right that it is a scourge on our environment and anything that can help to protect our forestry, ecosystems and woodland environments is important, which is why there may be a future for precision breeding in some of these areas.

Precision breeding could be particularly beneficial to speed up the breeding process in species that take a long time to mature—for example, to introduce disease resistance and drought tolerance traits in trees. This could have benefits for the forestry sector and for trees that are particularly susceptible to disease. As such, the definition of plants in the Bill is necessarily broad to allow for precision breeding and for the benefits to be realised in a range of species.

Our scientific advisory committee, ACRE, advised that precision-bred plants pose no greater risk to the environment than traditionally bred counterparts. It also advised that crosses between precision-bred crop plants and any sexually compatible wild relatives are extremely unlikely to result in weedier wild populations. Precision-bred plants are unlikely to be more invasive or persistent in non-agricultural settings compared to traditionally bred equivalents. This is because precision breeding relies on the creation of the same type of genetic variation as is selected for in traditional breeding.

The Bill introduces two notification systems. They require developers to provide information about precision-bred plants before they are released into the environment. Our intention is that this information would be published on a public register before the plants are released. I assure the noble Baroness that this will be closely monitored by the Government and, we anticipate, by stakeholders.

This Government have a strong commitment to protect and improve the environment, and we are clear that environmental protections are not being reduced in this Bill. Existing regulations such as the Wildlife and Countryside Act 1981 and the Natural Environment and Rural Communities Act 2006 will continued to apply to protect the environment from the introduction of non-native and invasive species.

I hope that reassures the noble Baroness that precision-bred plants pose no greater risk to the environment than traditionally bred plants, and that the Bill provides for proportionate systems to monitor developments in how these technologies are applied. I hope that she will feel able to withdraw her amendment.

The noble Lord, Lord Cameron, raised some interesting points. If he will forgive me, I will keep my powder dry until we get to the group beginning with Amendment 19, later in today’s proceedings, because that is where I can best address his concerns.

I turn to Amendment 31, which probes how the use of a precision-bred organism may impact on agricultural processes and systems. As I have previously outlined, we see precision breeding as an essential part of our toolkit to improve our food system. We are already seeing promising research in which precision breeding could positively impact agricultural processes, such as by reducing the need for pesticides and fertilisers and reducing water use.

In countries such as Argentina, where the use of precision breeding has already been regulated in a more proportionate and cost-effective manner, there has been an increase in the variety of beneficial traits being researched. We hope to see a similar outcome in England. This would enable our farming system to benefit from new varieties and breeds that have improved climate and disease resilience and pest tolerance, among other things. We do not expect one trait, product or company to dominate the market and shape agricultural processes in England.

Existing regulations related to plant variety registration, seed certification and seed marketing already deliver an assurance of quality and stability for most agricultural crops. For some agricultural crops, this also includes additional testing for value for cultivation or use. If such crops were to be developed by precision breeding, they would also fall under these regulations.

Precision breeding has the potential to bring positive impacts for farmers and the environment, and we want to encourage that. To encourage this innovation and investment, we need to create a more proportionate and science-based regulatory regime. That is what we are trying to achieve in the Bill. I hope that provides the reassurance that noble Lords require.

[Lord Winston (Lab)]

Does the Minister see this extending to non-food crops?

[Lord Benyon (Con)]

As I said, I can see this finding a use in forestry and in some ornamental crops. I think the early work will be done in areas that I outlined, including drought resistance and reducing the requirement for input such as fertilisers and sprays, but we want to include the ornamental sector in time. There are 30 million gardeners in this country, and we want to unlock their potential to be part of a great green revolution, but I do not think that that will be the priority here. The priority will be food.

[Lord Winston (Lab)]

Then why not restrict the Bill to agriculture and horticulture? There are, of course, mechanical engineering reasons for wanting some plants or indeed animals for non-food purposes.

[Lord Benyon (Con)]

With respect, I would not want to do that. In the same way that we are insisting that these measures can be achieved over a longer period of time through traditional plant-breeding techniques, if they are safe, it can be applied for food crops and in protection of our trees and woodlands, and it may have applications in other areas which will help our economy, particularly our green economy. I would not want to restrict it from those sectors.

[Baroness Jones of Whitchurch (Lab)]

My Lords, I thank the Minister for that response. I accept, as several noble Lords have said, that there is a role for gene-editing techniques in breeding disease-resistant trees. My noble friend Lady Wilcox gave the good example of ash dieback and we can think of other examples of such applications.

The Minister seems to be going gung-ho for all markets, if I could put it like that. I caution against that. As I said earlier, we need to do this step by step. We all understand the pressure to feed the nation more productively, but I am not sure that it is a priority to go beyond that to things that are more decorative, for example, even if there is a market at this time. I would have liked the Government to have had a more balanced view to this, but I will study what the Minister said more carefully in Hansard.

Moving on to Amendment 31, I do not think the Minister actually answered the fundamental question, which is whether the advisory committee will be asked to look at the wider implications for agriculture of these particular techniques. Will it be looking purely at whether the individual genome is safe or at how it might impact on the wider landscape, if it is planted in the wider landscape? All we were asking is whether the advisory committee will be given that role. The noble Lord mentioned other pieces of legislation, but we should not have to rely on them to make sure that the environment is protected. It would be nice to see that written into the Bill.

[Lord Benyon (Con)]

I will just answer that precise point. That is very much what ACRE does. It would not just be restricted to looking at a narrow area of science but the wider implications of the release into the environment and any impacts that that could have.

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The Minister has talked about the need to future-proof. I absolutely understand that, but we need to have those timescales—those restrictions, if you like—about when things can happen laid out clearly in the Bill. We will come to group 5 on implementation shortly, and I am sure we can look at this further then. There will also be more debate around animal welfare in group 8. However, I am concerned that we are moving forward without the information and the right regulation in place at this stage.

[Lord Benyon (Con)]

My Lords, when I was in another place, there was a free vote on the smoking ban. I remember a panicked Back-Bencher coming towards the Lobbies and saying that he did not know how to vote, because he hated smoking but loved freedom—what was he to do? Someone just said to him, “That way for freedom from smoke; that way for freedom to smoke.” I mention that because it shows that you can look down two ends of a telescope and come at this from two directions. I entirely understand that people who want to oppose the Bill in its entirety will find hooks on which to hang that belief, and that others who see merit in this will try to see a path down which to go.

I will try to address the points raised. First, for clarity, I say to the noble Baroness, Lady Bennett, that fungi are out of the scope of the Bill. I am sure she will be pleased to hear that. I say to the noble Baroness, Lady Jones, that animals were not a late inclusion into the Bill. There was a consultation in March 2021 which included animals, and a response to that was published in September 2021, so I do not think the idea that this was a late entry into the Bill stacks up.

I am grateful for the opportunity to further build on the Government’s position on why we think it is vital that animals remain part of the Bill. There are many potential benefits of enabling precision breeding in animals, including, as we have heard, to improve the health, welfare and resilience of animals. We have a real opportunity to harness the great research that is already taking place in the UK. Noble Lords highlighted some of this great potential during Second Reading, but to reiterate, our leading scientists are already using precision breeding to develop resistance to a range of diseases that impact animals across the country.

We have already mentioned at Second Reading research focused on resistance to bird flu in chickens, resistance to sea lice in farmed salmon and resistance to porcine reproductive and respiratory syndrome, which was mentioned by the noble Lord, Lord Trees—

[Lord Winston (Lab)]

I have been looking very carefully at the literature on gene editing for this debate, to remind myself. Although the Minister praises British research—of course we like to promote British research and British universities, being at one myself—I have to say that what I see is that the papers describing the risks of gene editing in detail largely come from other countries, including Asia and America. I do not think we can ignore the fact that there is a wide body of opinion that recognises that this is still a relatively dodgy technique, particularly so in animals, and therefore we need to go carefully before we start to implement it as a sort of service that we might be able to sell.

[Lord Benyon (Con)]

I am grateful to the noble Lord and will cover that point in a moment.

I was making a point about PRRS, but there are also developments abroad in producing cattle that are more heat tolerant and resistant to climate change. As was pointed out at Second Reading, there is potential to reduce methane emissions from cattle, which is vital for more sustainable agricultural systems.

I agree with the noble Lord, Lord Trees, that there are many examples that demonstrate the potential to bring significant health and welfare benefits to our animal populations and economic benefits to our farming industries. That is why we are looking at this down one end of the telescope. I hope I can persuade noble Lords that this a way that offers great potential, particularly in the area of animal welfare.

It is vital that we create an enabling regulatory environment to translate this research into practical, tangible benefits. This is a key objective of the Bill, and removing animals from the Bill would hinder us from realising any benefits of these technologies for animals. Ensuring that these technologies are used responsibly and enhance animal health and welfare is vital; I think we are all agreed on that. That is why we intend to take a stepwise approach in implementing the Bill, with regulatory changes to the regime for plants first, followed by that for animals. We want to make sure that the framework for animal welfare set out in the Bill is effective, and we will not bring the measures on precision breeding into effect for animals until this system is in place.

It is important we get this right, and that is why we have commissioned Scotland’s Rural College to carry out research to help us develop the application process for animal marketing authorisations. This will focus on the welfare assessment that notifiers will have to carry out to support their welfare declaration. This research will help us determine an appropriate welfare assessment for precision-bred animals and identify the evidence and information that must be submitted to the welfare advisory body along with the notifier’s welfare declaration. The research will involve experts from the Animal Welfare Committee and a wide range of organisations with expertise in animal welfare, genetics and industry practice.

As the noble Lord, Lord Trees has noted, the Bill introduces additional animal welfare standards, over and above existing animal welfare legislation. We are clear that these additional safeguards will complement our existing animal welfare regulatory framework for protecting animals. This includes the Animal Welfare Act 2006, the Welfare of Farmed Animals (England) Regulations 2007 and the Animals (Scientific Procedures) Act 1986. A suite of legislation exists. I absolutely refute the points that have been rightly raised that this can be seen as a fast passage towards higher density occupation of buildings because birds are somehow resistant to diseases caused by tight accommodation. There is already legislation that controls the densities and other animal welfare provisions. The idea that this is somehow going to allow producers to get round existing legislation is not the case, and there are additional animal welfare safeguards within the legislation.

If we want to drive investment in new research and realise the potential benefits for animals, we need to include them in the Bill. By doing so, we are providing a clear signal that the UK is the best place to conduct research and bring products to market.

I move now to the topic of limiting the scope of the Bill to certain animals. As we have already discussed, we know that there are benefits from enabling precision breeding. This technology has the potential to improve the health and welfare of animals. This applies to a range of animal species. I hope that the points I am coming to now will address the points made in the amendments and the remarks of the noble Lord, Lord Winston, the noble Baroness, Lady Bennett, and others.

The definition of animals in this Bill is broad so that the legislation remains durable for future years and to encourage beneficial research and innovation. Much of current research is on animals used in food production. We want to ensure that the potential benefits, such as improved welfare, can be realised across different species in a responsible way as research advances. This includes species that are kept only in this country as companion animals. Independent scientific advice that precision-bred organisms pose no greater risk than traditionally bred organisms applies to farm and companion animals.

To quote one example, hip dysplasia in certain breeds of dog is a devastating condition; it causes a lot of misery for the dog and its owners, and results in the dog’s early death. I do not say that there is some quick and easy path to resolving this, but there is a lot of research going on to traditionally breed out that condition. I want to see this sort of work speeded up. It seems right to include the ability to tackle these sorts of conditions in companion animals in this legislation, with adequate safeguards.

It is important to note that this is just the beginning. We intend to take a step-by-step approach with animals. We will not bring the measures set out in this Bill into effect in relation to any animal until the system to safeguard animal welfare is fully developed and operational. This system is intended to ensure that, before a vertebrate animal or its qualifying progeny can be marketed, their health and welfare will not be adversely affected by any trait that results from precision breeding. As I said, we have started by commissioning Scotland’s Rural College to conduct research that will help develop this application process.

I acknowledge the amendments tabled by noble Lords in relation to the range of animals covered in the Bill. The suggestion from the noble Lord, Lord Krebs, to pursue and build up the step-by-step approach is the right way forward. I hope that noble Lords will be reassured to know that the Bill, as currently drafted, already allows us to take this step-by-step approach through commencement regulations; for instance, by commencing the relevant provisions of the Bill in relation to some animal species before dealing with others. I hope this offers some reassurance to the noble Lord, Lord Winston. I hope that the points I have made will enable noble Lords to not press their amendments.

[Lord Trees (CB)]

On companion animals, I can understand that this is a difficult and quite controversial issue. There is an irony and a paradox—for example, around short-nosed dogs; the so-called brachycephalic breeds—and we can look at it with either a glass half full or a glass half empty approach. The irony is that, through natural, traditional breeding, we have bred animals that are deformed. Brachycephalic breeds have a markedly reduced life expectancy than breeds with long noses. They have not only problems with obstructive airway disease but delivery by Caesarean section is much more frequent, and they have ocular and skinfold problems. Genetic manipulation and editing could help reverse these trends much more quickly than might happen through traditional breeding. We need to be open minded about the potential for good, as well as the potential for less good outturns.

[Lord Benyon (Con)]

I totally agree with the noble Lord: there are opportunities here. With the balanced approach that we have taken and the step-by-step approach with which we will implement the legislation, I hope that we can quickly get to the place that the noble Lord described, where we start to reverse some of the terrible things that we have seen in traditional breeding processes. I hope that the Bill can be seen as paving the way for higher standards in animal welfare for all kinds of animals.

I am about to sit down, but I can see various noble Lords poised to step in and I am very happy to take more points.

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[Lord Benyon (Con)]

All I can do is assure noble Lords that nothing will happen before we are in the right position to do it. That is why we have commissioned the work with Scotland’s Rural College, and we are working with important stakeholders such as veterinary colleges and others to make sure that we get this right.

The priority will be to try to do this for farmed animals first, and we want to make sure that we are operating a step-by-step approach. If we put it in the Bill, it may be too prescriptive, because we are in a fast-moving area of science, and it may constrain the ability of the scientific community to progress this if we do it in the wrong way. We want to give as much freedom as possible, and that is why we are adopting this process.

[Lord Winston (Lab)]

I hope the Minister will forgive me—I have been a complete pest to him this afternoon and will probably continue to be one—but it is nothing to do with the scientific community. That community can take as long as it wants to get the right answers; it is the marketing of these animals that concerns us. We have no problem with the science, providing it is done humanely, and we recognise that that is the Government’s intention because we already have very good legislation to do that, but we have to accept that the science is still uncertain. That is why we are concerned that we might make mistakes.

[Lord Benyon (Con)]

That is precisely why we want to have the proper regulatory framework in place, and that requires consultation. We also have a flowchart, available on the Bill webpage, that sets out very clearly the process for applying for an animal marketing authorisation. I will not delay noble Lords by going through each of the six steps in the process, but it is very extensive and exhaustive and clearly sets out how we propose to do this.

It gives the kind of reassurance that a lot of noble Lords talked about regarding the public’s acceptance. To address that point, it is a matter of how you put the question: if you do so in the way in which the noble Lord, Lord Trees, just did, mentioning the benefits of the legislation, I think a huge majority of people will support it. If you ask it in a different way, you will get a different answer—that was the problem 25 to 30 years ago.

The noble Lord is right, of course: the scientific community will move at the pace that the money allows it to, and the market will create demand for the research. But we want to make sure that we have a good, proper regulatory process that reassures the public and is clear to developers of these products, so that they can see how they will be required to sit within that sort of framework.

[Baroness Bennett of Manor Castle (GP)]

I thank the Minister for his answer and thank everyone who contributed to what has been a very rich, full and very informed debate. I am going to deal first with the structural questions just raised by the noble Baronesses, Lady Hayman of Ullock and Lady Jones of Whitchurch.

We again have this problem that we have to wait for the regulations and trust the Government. I appreciate that the Minister was doing his best to persuade us, and I felt that he really wanted the opportunity to have a PowerPoint presentation here to show us a slide of his flowchart. But this is all about taking it on trust. Almost certainly, in the timeframe the Minister referred to, we are talking of not the same Government implementing this—I am not casting any aspersions on who the next Government might be—and the noble Lord not being in a position to guarantee what will happen in the future. We are left with this uncertainty and it not being clear. We know that tomorrow will test your Lordships’ House on just how much it is prepared to stand up against regulations. We shall see what happens then.

The Minister responded to me on the standards of what I call factory farming. He said that there is already legislation on this, but I say that that legislation is grossly inadequate and that we have huge disease problems because of that. Tightening up animal welfare regulations and regulations for housing animals in this country would greatly reduce the need to deal with problems of disease.

It is interesting that the Minister also said, perhaps a couple of times, that including animals is about making the UK the best place to conduct research. I come back to the point I made on an earlier group about whether this Bill is for animal welfare, food security for farmers, or for our biotechnology industry. It appears that we are hearing that it is for the biotechnology industry.

I am not going to run through all the contributions, because the noble Baronesses, Lady Parminter and Lady Hayman, have already provided us with a good summary, but I will draw together the responses from the Minister and a number of others, including the noble Lords, Lord Trees and Lord Cameron of Dillington. There have been suggestions about tackling disease, but we are talking about ecological niches here. Let us say you produce pigs that are entirely resistant to a particular disease; you are producing resistance to one species or one threat. You are very unlikely to produce widespread resistance, so you are opening up an ecological niche for another disease to come in, if you keep animals in conditions that allow that to happen.

We can take a practical example from what is happening in human society at this moment. Over many centuries, human societies have had conditions that have allowed the spread of a wide range of respiratory diseases.

[Baroness Bennett of Manor Castle (GP)]

I thank the noble Lord for his intervention and agree, although we know that animals kept in good conditions of husbandry are much less susceptible to disease. My first approach is to keep animals in conditions where they are not susceptible to disease, and then you do not need to go to the expense and effort of developing vaccines or using antibiotics, which have the issues with resistance that were raised by the noble Lord, Lord Cameron.

I was talking about respiratory viruses. Our population is threatened now by not just Covid-19 but a number of other coronaviruses that have long been causing respiratory diseases in humans. We are threatened by rhinoviruses and by flus, all because of conditions that make us prone to respiratory illnesses spreading. Tackling just one of those, as we have done with the Covid-19 vaccine that the noble Lord just referred to, with great effect, does not mean that we will stop all those other forms of respiratory illness.

That has covered the main points. I want to come back to the amendment from the noble Lord, Lord Winston, which raises some interesting points on great apes. I would extend this to all simians or monkeys. I ask your Lordships’ House to consider whether we actually want to be gene editing great apes or monkeys.

The point about equines is also very interesting when we think about horseracing and the enormous amount of money and the possibly shady characters involved in it. Whether we really want to see gene-editing in racehorses leads us into the companion animals question. It is a real area of concern. On that, the noble Lord, Lord Trees, referred to brachycephalic breeds that are identified as a problem area. If the breed societies were to say that they were going to create really rigid rules and change their definition of what those breeds are supposed to look like, that would be another way, a kind of husbandry way, of tackling the issue.

I will of course withdraw the amendment at this stage, but before I do that, I want to ask the Minister a question. Following on from the noble Lord, Lord Winston, does he think we should leave open the possibility of gene-editing great apes?

[Lord Benyon (Con)]

I do not think that any conversation I have had has considered what our priorities would be. Our priorities would be to look at farmed animals and possibly the benefits for companion animals. We are not a range state when it comes to those sorts of animals, and I cannot see that being a priority.

[Baroness Bennett of Manor Castle (GP)]

I thank the Minister for his answer, but I note that the Bill allows that to happen. There is nothing in it to say that it would not. I have no doubt that this is an issue that we will return to on Report, probably at some length, with a number of choices before us. I beg leave to withdraw the amendment.

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[Baroness Wilcox of Newport (Lab)]

I am grateful to the noble Baroness, Lady Bennett of Manor Castle, for tabling Amendment 12, and to the noble Lord, Lord Krebs, for tabling Amendment 74, which my noble friend Lady Hayman of Ullock was pleased to sign. Issues around intellectual property were not explored in any detail in another place; nor did the topic feature heavily in the Hansard report of Second Reading. Some may argue that such matters are pushing the scope of this legislation, but we believe it is vital that all interested parties understand the regimes that will apply once the Bill is passed and enacted.

For a product to make it to market, it will have been subject to research, testing, scaling up and the release and marketing processes laid out in the Bill. This will involve significant costs for those who develop the technologies and associated products. We understand that they will want to protect that work and the underlying financial investments to the best of their abilities. On the other hand, for this process to be successful, we need to see fair prices for the farmers who will utilise these technologies or the new plant and animal varieties that arise from them. At present, it is not clear what IP regimes will apply. We can make assumptions, but there is no certainty. As a result, we do not know how many players will bring these new products to market, nor how many farmers will be able to afford them. Amendment 74 offers a way forward, requiring the Secretary of State to publish guidance on these matters prior to bringing the bulk of the Bill’s provisions into force.

These matters are incredibly complex and perhaps not best dealt with through additions to the final version of the Bill. However, this is Committee, and we hope that the Minister will be able to provide an indication that this work is not only in progress, but that appropriate guidance will be in place at the earliest opportunity.

[Lord Benyon (Con)]

I thank noble Lords for their amendments regarding intellectual property laws. I will first take the probing amendment in the name of the noble Baroness, Lady Bennett of Manor Castle, which would prevent an organism from qualifying for precision-bred status if it was subject to a patent, either on the product itself or on the process used to produce it. This provides an opportunity for us to explore how a precision-bred organism can be patentable, and what it means for such an organism to be capable of having

“resulted from traditional processes or natural transformation”.

As I am sure she is aware from previous debates in Committee, it is the final genetic composition of an organism that we are considering when assessing whether a plant or animal meets the criteria for being “precision bred” as set out in the Bill. This is in line with the scientific advice we have received: that it is the final genetic and phenotypic characteristics of an organism that are important and not the technology or process used to produce it.

This approach differs fundamentally from the current principles used to determine whether patents are available for plants and animals whose DNA has been altered using modern biotechnology. Unlike the definition employed in the Bill to determine whether an organism is precision-bred—which, as I have said, focuses on the end result—patent principles focus on the technology or processes used to produce these plants and animals.

The definition of a “precision bred organism” should continue to be based on scientific evidence and advice. In continuation of this logic, it would be disproportionate and unscientific to prevent a qualifying precision-bred organism from having precision-bred status on the basis of the granting or not of a patent. To prevent precision-bred organisms from obtaining patent protections would go against the core principles on which the Bill is based: that regulation should be proportionate, robust and driven by the evidence.

An invention must meet a number of legal requirements if a patent is to be granted. The granting of a patent is determined not only by the nature of the invention but by other legal requirements, including whether the invention is new or non-obvious. This is not the same as asking whether an invention that did not exist previously could, in principle, have been produced through a different method. As such, the presence or absence of patent protection cannot be used to determine if a particular DNA sequence could have resulted from traditional processes or natural transformation.

Patents represent an important mechanism for innovators to gain return on their investments. As a result, preventing organisms from being classed as “precision bred” if those organisms or the processes used to create them are subject to patent protection, would likely deter uptake of the technologies that the Bill wishes to facilitate. Ultimately, the UK would lose the significant benefits that implementation of the Bill could bring.

Amendment 74 would require the Defra Secretary of State to review and publish guidance on the implications of the genetic technology Bill for intellectual property law. As I am sure that noble Lords are aware, in the UK the Intellectual Property Office is responsible for patents. I assure noble Lords that we have worked closely with the Intellectual Property Office in this area. UK patent law does not specifically exclude patents from being granted on precision-bred plants and animals. Indeed, a patent may be granted if all the requirements for a particular invention are met—novelty, utility, and non-obviousness.

The Bill does not make any changes to laws associated with obtaining a patent; nor does it alter the process by which an applicant would apply for patent protections. Breeders wishing to patent their precision-bred plant or animal should therefore undertake this process in the same manner as for all other inventions and under the guidance of the Intellectual Property Office.

Most interest in this area has revolved around the use of patents that protect precision-bred organisms. However, it is important to note that other protections for intellectual property are available. For example, a plant breeder may want to obtain protection using plant variety rights. In animals, breeders generally gain protections through contracts with buyers, which stipulate terms to ensure their trait of value is protected. Engagements with industry stakeholders have highlighted that fair access and value gains for farmers must balance with restrictions on the use of protected material in order to enable a return on investment. In plant breeding, licensing platforms which facilitate access to patented material have been borne out of the need to create this equilibrium. We envisage that a similar situation would arise should breeders decide to protect their precision-bred organisms. Ultimately, patent law strikes a balance between incentivising innovation and allowing access for farmers and breeders, precisely the point that the noble Baroness, Lady Wilcox, was making.

[Lord Krebs (CB)]

I do not know who drafted this response but it is a masterpiece of obscurantism, in my view. I do not blame the Minister; he is simply reading out what his civil servants have given him. I could not understand—maybe because I am falling asleep or something, but I do not think I am—whether the answer is that PBOs are equivalent to the plants or animals that could be produced by conventional breeding, and therefore enjoy the same protections, or whether they are different. Will he just nail that point down, with a very simple yes or no? Is his answer that precision-bred organisms are treated as equivalent to those that could be produced by conventional breeding, and therefore they enjoy the same patent protections?

[Lord Benyon (Con)]

I apologise to the noble Lord if I am sending him to sleep, but this is a complex area. Patent lawyers will dance on the head of a pin on some of these issues. As I said, we have worked with the Intellectual Property Office to get this exactly right and to address precisely the point he made earlier about some of the difficulties that were faced, with large international companies owning the rights to seed entitlements. That caused great difficulty in the past.

I shall just read one bit to him again, and if the noble Lord could try to stay awake, it will be an achievement that I will rejoice in. The Bill does not make any changes to laws associated with obtaining a patent; nor does it alter the process by which an applicant would apply for patent protections. Breeders wishing to patent their precision-bred plant or animal should therefore undertake this process in the same manner as for all other inventions and under the guidance of the Intellectual Property Office.

The Bill is also an attempt to provide precisely the balance that the noble Baroness, Lady Wilcox, stressed. We want to secure the rights of those who are investing enormous amounts of money in the development of these technologies, while also not making it impossible for farmers—precisely the people we want to have access to these technologies—to have access. That is the balance we are seeking to achieve.

I can work only on the best legal advice I am given. There are noble Lords in this Committee whose speciality is intellectual property law, and I am sure they could dance much more dextrously on the head of that particular pin than I.

[Lord Winston (Lab)]

I wonder if we could “strictly” stop dancing just for a moment and come back to the question of the noble Lord, Lord Krebs. I have to declare an interest in the register: I have a company called Atazoa, which is responsible for modifying the genes not of embryos but of individual sperm. We have of course also been working with eggs. This is before fertilisation—before the organism is formed. That is subject to a number of patents which have raised a certain amount of money for our research, and the research has been moderately fruitful—not as fruitful as I would have liked it to have been; it has not made any major changes.

There is an issue here. First, what happens if we produce a farm animal as a result of that technique? Does that come under the licence or not? Secondly, during the process of gene editing, it is very probable that people will make new editions to the modification of techniques to find new ways to put together what is quite a complex process; even though it is fairly efficient and simple to do, it remains complex. What happens, for example, with regards to improvement of the technology, rather than the animal husbandry side of it? Does the patent there still stand or not?

[Lord Benyon (Con)]

I have to be honest with the noble Lord and say that I will write to him on this. He makes a very good point. I can think of it only in terms of a standard invention. In intellectual property terms, you secure the creation of whatever it is, with whatever characteristic it has, and others may come along and improve it. The line on intellectual property exists until they change it beyond its original purpose, and I quoted the other criteria earlier. I am going to write to both the noble Lord, Lord Krebs, and the noble Lord, Lord Winston, to give more precise answers to those particular points. With that, I hope the noble Baroness is willing to withdraw her amendment.

[Baroness Bennett of Manor Castle (GP)]

My Lords, I thank the Minister for his answer and everyone who has contributed to this short but very dense—I think that is the appropriate adjective here—debate. I cannot help feeling that, should we revisit this on Report, as I suspect we may, we will need a couple of IP KC specialists to hand it over to, rather than leaving it to be tangled with by those who are not legal specialists in this area. The noble Baroness, Lady Wilcox of Newport, nailed it: it feels like this has not been properly worked through, and it certainly has not been explained to the Committee. That is exactly where we have arrived at.

I will put some more questions to the Minister, because I am wrestling with this. I freely acknowledge that I am not an IP law specialist, by any means, but how can something that is patented be natural and traditional? Those two things are simply incompatible in law, and certainly in public understanding. That is what my amendment addresses, and I do not believe the Minister has dealt with that issue.

More specifically and concretely, and perhaps easier to answer—although I understand if the Minister wants to write to me—he referred to some of the tangles that had occurred previously with GMO technology. Seeds had blown from one field to another, and a farmer who had not even planted the patented crop found themselves in legal difficulty with its owner because they were illegally growing the seeds, even though they did not want them. Some of them may even have been organic farmers, who definitely did not want those seeds. Can the Minister assure me that we will not see this situation arising with so-called precision-bred organisms in the UK, particularly plants in this case—I am not sure we are talking about animals as much? Also, what happens if a genetic trait cross-breeds with or appears in a weed? Who is responsible for that? Is the owner of the intellectual property responsible for what happens with the weed?

[Lord Benyon (Con)]

That last point would have been dealt with in the process for ACRE’s analysis of its worthiness as a precision-bred organism that can be taken to market, as it clearly does not sit within the intent of the applicant.

All I can say to the noble Baroness, as I said earlier, is that we want to achieve a balance in encouraging the development of this. She was wrong earlier to say that this is just for commercial activity. It is very much not. There are other benefits, public goods, that the Bill achieves in animal welfare, tackling climate change, improving our environment, and reducing the requirement for pesticides and fertilisers. Just as there is a balance between those public goods and encouraging commerce and the ability of organisations to take products to market to be of advantage to the UK economy, the Bill also tries to achieve a balance between securing the intellectual property rights of those who have invested large amounts of money in the development of precision-bred organisms and the importance of making those organisms available to precisely the people who we want to have them. In most cases, that will be producers of food.

[Baroness Bennett of Manor Castle (GP)]

I thank the Minister for tackling those questions. I feel that it might be best for me to write to the Minister to spell out the details of the questions that I am not sure I am sufficiently equipped in the IP area to formulate now. We are going to revisit this at Report, and I do not think we have heard any kind of argument against Amendment 74 and the idea of a review. In the meantime, however, I beg leave to withdraw the amendment.

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[Baroness Hayman of Ullock (Lab)]

My Lords, I thank the noble Baroness, Lady Bakewell, for introducing her Amendment 16. As we have heard, there are a few amendments in this group around trade, particularly in relation to the EU and individual member states. Amendment 16 specifically refers to this. It is an important consideration for the Bill and its implications

The noble Baroness, Lady Bennett of Manor Castle, has tabled a number of amendments in this group. I also thank her for her introduction. I have added my name to her Amendments 75 and 78. As Amendment 75 says, it is really important to review the effectiveness and implementation of the Act once it is passed. The Minister has talked about a step-by-step process. I shall come to that as well in my amendment. As I mentioned on the previous group, there are still a lot of unknowns and a lot of SIs to come into play before we know exactly what the legislation will look like. A commitment to a review is pretty important to make sure that everything is happening as the Government intend and to see whether anything needs to be picked up that is perhaps not moving as they would wish. My noble friend Lord Winston made the important point that we need more data on animals. A review would help to look at where we were.

Amendment 78, to which I have also added my name, requires the Secretary of State to have regard to the impact on SMEs, for example. The noble Lord, Lord Cameron, mentioned the importance of supporting small businesses. From reading the Committee evidence in the Commons, I recall that there was quite a lot of debate around the importance of small businesses also being able to benefit from this legislation and not being pushed out by the larger companies. I would be interested to hear from the Minister how the Government intend to ensure that small businesses are allowed to play a full part in any legislation that comes from the Bill when it is enacted.

On a different topic, my noble friend Lady Jones of Whitchurch probed concerning Section 41 in the Environmental Protection Act. Again, this is a really important point. There are different pieces of legislation covering very similar areas. How do they interact? She asked an important question about when the review on wider GMO rules would take place. Once this review has reported, how will the outcomes be managed in relation to the new legislation that is coming forward? Not all legislation sits in its own little place. Lots of legislation interacts, at the Minister well knows. It would be good to know that the Government are looking at this, thinking about it and to know when they were likely to do a review.

I will come on to my Amendment 89 in a minute, as it is a little different. But briefly, on the trade implications which we touched on previously, the Food and Drink Federation has said, for example, that there could be barriers to exporting English farmed food from gene-edited crops. Again, it would be interesting to hear the Minister’s thoughts on this. We also talked earlier about what the impact of a difference in definition would be, and that comes into play here as well. At the end of the day, any commercial cultivation of plants or food products that are derived from gene-edited crops will still fall within existing rules. We know that the EU is reviewing where it is, but it is important that we do not end up with negative impacts on our farmers and exporters in food products because we have not thought this through properly.

Perhaps the Government could reassure us that that they are looking at the trade implications and whether they are considering any mitigating factors to ensure that there are no problems. The impact assessment says that it could

“have a relatively significant impact on UK producers”

if there are problems with exporting to the EU, because

“UK crop-related food exporters are heavily dependent on EU consumers’ demand”.

Again, it is important that we have those assurances. I know that the noble Lord, Lord Krebs, is concerned about the word “risk”, but there are risks to exports which the Government need to recognise.

In looking at whether products are going to be accepted, I want to ask about Scotland. I am concerned that the Minister in Scotland said that they would not have any food products forced on them because of easing regulations around gene editing. That concerns me because, if we are not careful, we will have a constitutional flashpoint. Our single market rules say that any produce approved in England is automatically then allowed into Scotland, so what ongoing discussions are the Government having with Scotland on this and what mitigating circumstances can be brought in? That is a worry.

Finally, my Amendment 89, which I have left to the end because it is different from the others, brings me back to where I was on the step-by-step approach. I asked the Minister whether he would consider that; I know he has reassured us, over and again, that precision-breeding technologies will be used first in relation to plants, followed by animals later. But not to put too fine a point on it, we have only his word for that—and while I trust his word, we do not know who the future Ministers or Secretaries of State will be. My amendment makes a suggestion that he could pick up, so that we genuinely would have a step-by-step approach in the Bill. It would be plants first, then farm animals, and then other animals could be looked at. Again, I am only trying to be helpful to the Minister in supporting his step-by-step approach.

[Lord Benyon (Con)]

I appreciate that, as keen as I am to get this right and get something sensible on the statute book. I have a throwaway line before I get into the meat of it. The noble Baroness, Lady Bennett, talked about this being controversial legislation. Actually, in some of the surveys I have seen, a very small number of people are either very opposed or very in favour, and a large number do not know what this is all about. They want to know more, and we have to tell them more. We have to explain it in an unbiased, unpolitical, factual way, and that is what we are seeking to do. In the other place, the Bill passed by a majority way in excess of the Government’s majority, and I want to reassure many noble Lords here, so that we can pass it with equal fervour.

Smarting from the earlier comment from the noble Lord, Lord Krebs—

[Baroness Bennett of Manor Castle (GP)]

I think the Minister tried to suggest that the legislation was uncontroversial. We were before discussing the inclusion of animals in the Bill, and 13 of what I think would be universally agreed to be the premier animal welfare organisations in the UK have said animals should not be in it. That surely is controversy from people who are very informed about its nature.

[Lord Benyon (Con)]

I accept the point the noble Baroness makes, and of course, there are others who fervently want measures brought in as quickly as possible that deal with animal disease, animal welfare and those sorts of things.

As the noble Lord, Lord Krebs, quite rightly upbraided me earlier for boring the House, I will try to be as quick as I can, but there is a lot in this section, and I want to be open with the Committee in my comments.

I will respond first to Amendment 16, which would require the Secretary of State to consult, first, representatives of a number of interested groups and then European partners including but not limited to the EU and its member states. This is to agree on a definition of precision breeding and, if a definition is agreed, to amend the definition of a precision-bred organism in the Bill accordingly, using a Henry VIII power. The amendment could be used to change the key concepts that form the basis on which this legislation has been drafted and debated in both Houses of Parliament.

This summer, the EU conducted a consultation in which 80% of participants agreed that the existing provisions of the EU GMO legislation are not adequate for plants produced by certain new genomic techniques, which largely aligns with our view of precision breeding. As I have previously mentioned, the definition of a precision-bred organism in the Bill aims to cover all plants and animals produced by modern biotechnology that could have occurred through traditional processes or natural transformation. This approach to carving out precision-bred plants and animals from GMO legislation is in line with scientific evidence and advice, because it focuses on the end product rather than the technology used to produce it.

Furthermore, we have continuously engaged with national and international stakeholders and regulators to develop a definition that reflects the key principle of this legislation. Our approach is based on the science. With regulations on precision-bred plants and animals changing around the world, we believe the measures in this Bill will facilitate greater trade.

On the topic of trade, I am grateful for the opportunity to discuss how differences in regulation and public perception in other countries will impact on our trade with them. Noble Lords have referred to genetically modified organisms in the amendment we are dealing with, and I want to be clear that there is a scientific distinction between GMOs and precision-bred organisms. Many countries recognise this and have changed, or are in the process of changing, their regulations to reflect it. As the international regulatory landscape evolves, our approach could help facilitate greater trade with countries that have already adopted a similar approach to the regulation of precision-bred organisms, with trading partners such as the USA, Canada, Japan and Argentina.

Currently, there are only a few precision-bred products on the market globally, and none of those are traded internationally. Many of them are still in the early development stage, allowing time to monitor and understand the international regulatory framework as it develops. Britain is an exporter of quality products, and one of the reasons for introducing this new, proportionate regulatory approach is to enable the development of more nutritious, higher-quality products that have been grown more sustainably.

Turning to Amendment 77 and the remarks made by the noble Baroness, Lady Bakewell, I would like to outline developments that are likely to change the requirements for companies exporting precision-bred products specifically into the EU; we have been following these developments with interest.

As our legislation on genetically modified organisms mirrors the EU’s, it is not surprising that we have the same drivers for change. The timing of the EU’s reform plans means that we are unlikely to be able to consider any new EU legislation while we are drafting our regulations under this Bill. However, we will continue to monitor developments closely and work with the EU, and other countries we trade with, to enable innovation and trade. I hope I have reassured noble Lords on this.

--- Later in debate ---

[Lord Winston (Lab)]

I would love to hear from the Minister say “finally” again in just a second. One of the issues I would like him briefly to address—probably in a note, not now—would be how to classify a plant organism, for example, which has been treated not only by gene editing but also by, say, radiation. I mention this is because a recent publication by Amritha and Shah in the last few months shows that, by combining those techniques, the resulting edit is even more successful. It seems that is hardly a natural process, but I do not know whether that is something to discuss now.

The other issue is that we are all obviously agreed about climate change, but what I think concerns a lot of people who are arguing on my side of the Chamber is that modifying plants could make us, the plants or the land more vulnerable to climate change. That is something we need to be thinking about during the course of the Bill.

[Lord Benyon (Con)]

I take the noble Lord’s points. We have to make it clear that we will not allow organisms to come on to the market that would somehow make it harder for us to adapt. There are so many benefits that we can introduce to tackle things such as drought and other issues that plague farmers. We have climate change affecting farmers here and now in this country. It is not something that is happening in Pacific countries alone; it is in our country, and we need to give farmers the tools to deal with it.

On the noble Lord’s other point, as the noble Lord, Lord Krebs, said earlier, irradiation—if I have got the word right—is an established part of plant breeding today. He is right. I can see an overlap in this, but I will write to him and make sure that we give him the facts that he needs. With that, I hope that we can progress.

[Baroness Bakewell of Hardington Mandeville (LD)]

My Lords, although I thank the Minister for his response, I am obviously somewhat disappointed by it. I understand the desire of the noble Lord, Lord Cameron, to speed up the process, but I fail to understand how consulting with the EU would affect that. It certainly would delay it a little bit, but not by the years and years that the noble Lord indicated. I believe that a Bill introducing a process which alters the genome of crops and animals ought to have a review every five years. I accept that the Minister feels that there are sufficient reviews in place—I just do not necessarily agree with him.

The Minister spoke about a consultation that took place—he did not say exactly when it was, but I think it might have been last year—and said that 80% of those consulted said that the EU definition of precision engineering was not adequate, and that the end product, rather than the process, was more important. The Minister can write to me, given the hour, but I would like to know who was consulted—who were these 80% of people who said that the EU’s process was not fit for purpose? The Minister also said that the UK’s regulations mirrored the EU’s regulations and monitors; that conflicts with this figure of 80% saying that they were not fit for purpose. For me, it is smaller businesses that benefit most from trade with the EU rather than with Argentina, although I accept that some will trade with the latter.

--- Later in debate ---

[Lord Benyon (Con)]

My Lords, I am grateful for Amendment 19, which raises the importance of ensuring that what we do has a public benefit. Across government we are undertaking a range of what I believe is really exciting work to deliver public good and we want to see precision-breeding technologies complement this work to improve our food system and the environment.

On my phone I keep some crucial lines from the Agriculture Act, because when I meet farmers and they say that this Government no longer mind about food production I remind them that right at the front of the Agriculture Act, in Clause 1, it says:

“In framing any financial assistance scheme, the Secretary of State must have regard to the need to encourage the production of food by producers in England and its production by them in an environmentally sustainable way.”


That is a declaratory statement right at the front of the Act. What we are seeking to do in terms of environmental land management goes through the heart of that piece of legislation and this piece of legislation fits very firmly within that.

As noble Lords are aware, the UK is privileged in its scientific position and researchers across the country are already delivering exciting research that contributes towards public good in the field of precision breeding. In the other place, the John Innes Centre gave evidence about the vitamin D tomatoes that its research group is developing, striving towards improving the food we eat for the benefit of our health. Another notable example is from researchers at Rothamsted who are exploring ways to increase the lipid content of grasses. This could help improve the quality of animal feed and has the potential to reduce methane emissions in livestock. I think we are all proud of the work taking place in this country and I am sure that the noble Baroness, Lady Jones, is particularly proud of Rothamsted.

This amendment, I fear, might hinder the important research in this area by placing restrictions on and creating significant uncertainty for critical field trials for researchers and breeders attempting to make new varieties of precision-bred crops. While I understand the intention of this amendment—and it is an intention I applaud—it would not be appropriate to restrict technologies used in breeding, nor do we have any evidence that suggests developers are doing anything other than creating better and improved varieties or breeds.

Of course, it is important to note that these technologies are not a silver bullet, and we want them to be part of our innovation toolkit to improve our food system. Delivering public good is what I did say earlier, and I am very glad I did—and it has been underlined by other noble Lords. It is what we strive for across government and we are fully committed to developing a more sustainable, resilient and productive food system.

Noble Lords quite rightly referenced the Government’s food strategy and, building on Henry Dimbleby’s extraordinary, in-depth piece of work, we have set out a plan to transform our food system and ensure that it is fit for the future. The noble Baroness, Lady Bennett, mentioned sugar beet. This is a crop where there is an application which might be of huge benefit, and not just in terms of the food that we produce. Being able to develop a strain resistant to virus yellows would mean that we would not have to seek noble Lords’ permission through secondary legislation for a derogation to allow the use of neonicotinoids to control virus yellows. More importantly, we could have a crop that was not only able to produce more sugar for our producers here but would require us to import less sugar from abroad, thereby lowering the carbon impact of that crop.

There are counterfactuals in everything. Trying to improve the home-grown element of our food, while reducing the impact that failing to produce it at home would create by having to import that food, sometimes from far away, needs to be factored in. It is fundamental to our food strategy.

I thank the noble Lord, Lord Winston, for his Amendment 21, which would require the genomes of precision-bred organisms to be sequenced before they can be released into the environment, regardless of whether or not an organism with the same genetic changes had previously been assessed and classified as precision bred. It also stipulates that the genomic changes resulting from the use of modern biotechnology have to be recorded, that no unprecedented changes can be present in the plant or animal, and that this must be reported to the Secretary of State.

I assure noble Lords that the criteria for defining a precision-bred organism, as set out in Clause 1, consider both intended and unintended changes to the genome. This means that any changes resulting from the use of modern biotechnology, whether intended or unintended, must be able to occur through traditional breeding or natural transformation for a plant or animal to be considered precision bred. It also means that unintended changes will already need to be assessed as meeting these criteria before any precision-bred organism is released.

The noble Lord’s amendment would mean that plants and animals could not be classed as precision bred if they contain unintended genomic changes. Unintended genetic changes occur during the traditional breeding process. Some of these may be removed during that process and others not, as will be the case with precision-bred organisms. As I expect the noble Lord is aware, many recent gene-editing studies about animals have reported no incidences of unintended genomic changes when using CRISPR-Cas9. Having assessed this evidence our expert advisory committee, ACRE, has also advised that unintended genomic changes occur significantly more often during the course of traditional breeding than they do as a result of precision breeding. This is also the view of the European Food Safety Authority, which advises the EU. Consequently, while we expect developers to ensure that any unintended changes are within the range of what can occur naturally, the scientific advice we have received suggests that it is not appropriate to prevent plants or animals with unintended genetic changes from being classed as precision-bred organisms.

We are committed to taking a proportionate approach, requiring only the information that fulfils the regulatory requirement at the appropriate time. It is for this reason that the Bill distinguishes between requirements for research trials and marketing applications of precision-bred organisms. This amendment is likely to add regulatory burden, without adding value to the process. For example, developers would be required to submit a release notice to Defra, confirming that the founder organism they intend to release for research trials meets the criteria in the Bill. They would have generated genomic data to confirm that this is the case.

However, requiring whole-genome sequencing would be disproportionate, given the specific, targeted nature of changes being made. I assure the noble Lord that breeders who release an organism modified using modern biotechnology that does not meet the criteria outlined would be subjected to sanctions under existing GMO legislation. This is a strong deterrent against releasing organisms that do not qualify as precision bred. That also goes some way to answering the point that the noble and right reverend Lord tried to pick up from the previous group, which was not moved. However, we are clear about the sanctions that we want implemented.

Developers will have to submit an additional notification to Defra should they wish to market their precision-bred organism. Breeders will need to provide fit-for-purpose information to demonstrate that they have met the requirements that I have outlined. The technical details will be developed with the advisory committee appointed to advise the Secretary of State on the regulatory status of these organisms.

For marketing approvals, assessments will be carried out on a case-by-case basis. The full genomic sequence of an organism may not be required in addition to information on intended and unintended genomic changes to determine similarity to traditional breeding or natural transformation. As a result, we do not feel it necessary to include a provision that specifically requires whole-genome sequencing.

Finally, to address the noble Lord’s point that the DNA of all progeny of a precision-bred organism should be sequenced before release, if a “founder” organism has met the criteria laid out in the Bill—specifically, that the genetic changes made by modern biotechnology are stable and could have arisen naturally or through traditional breeding—we have been advised that the regulatory status of its progeny does not have to be assessed. This is because the changes made are stable and in line with those that occur naturally.

To address the noble and right reverend Lord’s point about this being a public good, I hope I have set out why the Bill fits in with the Government’s food strategy and how environmental sustainability will be enhanced by it if we get it right. Perhaps the greatest public good will be if we are able to adapt to and tackle elements of climate change that affect not just these islands but countries all around the world. It could benefit some very challenged environments, so we owe it to them to make sure that we are regulating this correctly, making it accessible not just to large multinational companies but to smaller businesses and—to use the rather pompous word I used earlier—democratising it, ensuring that its benefits can be felt far and wide. I hope this provides the assurance that noble Lords need not to press their amendments.

[Lord Krebs (CB)]

I thank the Minister, but I have one question of clarification, just to check that I have understood what he said—namely, while accepting that it is important that public goods are delivered by precision breeding, that it would in some way stifle innovation if one defined too precisely what one meant by “public goods”. Can the Minister give an example of where saying what one means stifles innovation?

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[Lord Benyon (Con)]

Whether I can give the noble Lord an example or not, I do not know, but he is absolutely right. That is why crafting this legislation has been such a monumental task. MPs in the other place and noble Lords in this place very often—and quite rightly—want to see as much as possible on the face of a Bill, because it holds current and future Governments to account. Very often, not having things on the face of a Bill can be exploited. However, putting too much on the face of this Bill, or being too prescriptive, could create a feeding frenzy for lawyers, be a burden on producers and have a stifling effect on innovation. I hope noble Lords will feel that we have got the balance right and are allowing enough flexibility.

I can see that there are elements of the regulatory framework that support this legislation that are yet to be developed in detail. I am very happy to give noble Lords as much information as I can on the process of developing that, not just now but, for example, as we get information from the Scottish colleges that will inform us on some aspects of the Bill, including this one. That will give the wider consumer and the concerned individual the information they need to know that we are being proportionate and are very focused on this key point of trying to make sure that we are providing a public good.

[Lord Winston (Lab)]

That was a very complicated statement. I think the noble Lord, Lord Krebs, had a bit of difficulty with it, and so did I, so I shall read it with great interest in Hansard. Perhaps we can discuss one or two issues that the Minister raised. I think he said, though maybe I misheard, that there have been no recorded changes in the genome or in the DNA of animals that have been modified using the CRISPR technology, for example. I should like to get back to the noble Lord in order to share with him my understanding and to present him with some reports from the literature which argues that this actually has happened and that the introduction of stray DNA, as well as off-target mutation, is a real issue. But now is not the time to discuss this. We shall probably have to leave it until Report.

I am sure that we are basically working towards the same thing. However, it seems to me that, if you own a picture—a Rembrandt, for example—you do not automatically sell it as a Rembrandt; you sell it for what you think it is worth, or what its provenance is. So the provenance of what we sell in terms of our animals to other people is just as important. It is part of a proper sale. If in fact it depends on the genome and the nature of the genes—whether they are expressing or not expressing, and whether the progeny is normal—that, I would argue, is important to the person who is going to buy it. It is essential that we try to be honest, open and transparent.

[Lord Benyon (Con)]

That is absolutely right. I would just say to the noble Lord that ACRE assessed the evidence put to it by the scientific community. I repeat what I said. Many recent gene-editing studies on animals have reported no incidences of unintended genomic changes when using CRISPR-Cas9. If the noble Lord has information that ACRE should be considering in relation to this, I would be very happy to connect him with ACRE. But that is also the same scientific opinion that was reached by the European Food Safety Authority, which advises the EU Commission. But the noble Lord is absolutely right that the science on this is moving. There are advances being made, not just here but internationally as well, and we must have the best possible advice to allow Ministers to take the best possible decisions.

[Baroness Hayman of Ullock (Lab)]

My Lords, I thank my noble friend Lord Winston for his amendment and for the discussion, but I do not feel qualified to comment on it any further than that. We are having an important debate in these areas, and his knowledge is really helpful and useful as we continue to debate the Bill.

On my Amendment 19, I thank all noble Lords for their support, particularly my noble friend Lady Jones of Whitchurch, the noble Baroness, Lady Parminter, and the noble Lord, Lord Krebs, for adding their names to it and supporting me strongly on this—I appreciate it. I am sure that noble Lords and the Minister will not be surprised that I am extremely disappointed in his response. As the noble Baroness, Lady Parminter, and my noble friend Lady Jones said, the amendment fits so well with the Agriculture Act and, as the Minister himself said, with what the Government are trying to achieve through the food strategy. I genuinely do not understand why it cannot be part of the Bill. The Minister said that the amendment was too restrictive, and the noble Lord, Lord Krebs, raised a question about this and asked for an example, which I am not sure we got. I ask the Minister again: how is it too restrictive?

I am not sure whether all noble Lords have seen the amendment, but it lists 11 different purposes—I tried to keep it broad. One of the 11 is

“protecting or improving the health of plants”,

and another is

“protecting or improving the health or welfare of animals”.

My amendment says that it has to be only “in connection with one” of the 11. In discussing the animal part of the Bill, everyone said the reason for having it is to improve health and welfare; I do not see how the amendment would not fit in with this. The same is true of some of the other areas around plants. I genuinely do not understand why it is too restrictive, and I would appreciate it if the Minister could perhaps think about that before Report, because we will come back to this.

Earlier, I said that, when making legislation, we have to ensure that, as well as welcoming those who are undoubtedly trying to do good, we must guard against those who are not. I think the Minister is looking through rather rose-tinted spectacles. On that note, I beg leave to withdraw the amendment.

Genetic Technology (Precision Breeding) Bill

Lord Benyon Excerpts

Report stage
Wednesday 25th January 2023 Lords Chamber

[Lord Curry of Kirkharle (CB)]

My Lords, I will briefly respond to the noble Lord, Lord Winston, on that point. It is a fair question, which we do need to respond to: what happens if we narrow the gene pool and expose animals to genetic risk? There has been evidence in the past that by narrowing the gene pool in dairy cows, we have had lameness problems; there has been an issue in other species. That is because we have not properly understood; indeed, random breeding, as the noble Lord, Lord Trees, has said, has resulted in that kind of action. Through better understanding of the genes, and through ensuring that we retain as wide a gene pool as possible from which to choose, but being selective and more careful and intelligent about the use of those genes, we should avoid that consequence.

[The Minister of State, Department for Environment, Food and Rural Affairs (Lord Benyon) (Con)]

My Lords, I start by reminding noble Lords of my entry in the register. This has been a fascinating opener for this afternoon’s proceedings. I know that this is an area of great importance to this House. I want to take account of the concerns raised in the debate and more clearly show our intention on this issue. Perhaps I should start by saying that, having been in, then out and now back in Defra over about a decade or more—and not being a scientist—I absolutely do take the point made by the noble Lord, Lord Krebs. I try never to use the words that the noble Lord, Lord Winston, attributed to me, which was that I was following the science. The science is imprecise, and what we have to do as policy- makers is take a view, listen to reputable people who advise us and organisations both here and around the world, and hope we get it right.

I shall say just two things at this stage of the proceedings on what my involvement in the Bill is not about. First, to tackle what the noble Baroness, Lady Bennett of Manor Castle, said—that this is somehow to satisfy the demands of the global agricultural corporations—no, it is not that. As far as I know, we have had no lobbying from any of those organisations, and this is about something else which I shall come to. Secondly, it is not about taking back control. For me, it is about looking at crops that I see frying in heatwaves that we never had when I was younger. It is about talking to farmers who have Belgian Blue cattle that can give birth to calves only by Caesarean section because they have been bred through traditional breeding methods in a way that makes natural calving impossible. It is about correcting some of those aberrations that have existed, as well pointed out by the noble Lord, Lord Trees. We can tie ourselves down with negativity about this, but the opportunities for this legislation, what it offers for animal welfare and for tackling issues such as climate change, are immense.

On the amendment to remove animals from the Bill completely, as was highlighted in Committee and in today’s debate, I say that it is vital that animals remain part of the Bill. We focused on farmed animals in debate because there is already research in the UK and abroad showing the exciting potential of precision breeding to help tackle some of the most pressing challenges to our food system, the environment and animal welfare. These challenges are significant, and while these technologies are not a silver bullet, they can work alongside other approaches to help us to improve animal health and welfare, enhance the sustainability of farming, and strengthen food security and resilience. It is vital that we create an enabling regulatory environment to translate the research that we have already highlighted in debates into practical, tangible benefits.

It is equally vital that these technologies are used responsibly. That is why we have included specific measures in the Bill to safeguard animal welfare. These go beyond what is required for traditional breeding and under current GMO requirements. We therefore do not see this legislation as a route to lowering welfare standards. Instead, we see it as a real opportunity to improve animal welfare and our food system.

The debate about outliers was fascinating. As a policymaker, I quite like challenging Defra scientists and those who advise us by pushing an outlying piece of science, something that may not even be peer-reviewed. It is one of my criticisms of the scientific lobby that, to get peer-reviewed papers, you have to be in the centre. In this case, I have looked at the broad range of views in the scientific community. I entirely endorse the sentiments put forward by the noble Lord, Lord Krebs. However, I understand concerns raised in the debate about the use of precision-breeding technologies in certain groups of animals, such as companion animals, and I recognise and agree with noble Lords on the importance of building confidence in the regulatory system.

There is a case for prioritising where there is the greatest research interest and where there are greatest potential benefits for animal welfare in our food system. That is why I want to make a commitment on the Floor of this House that we will adopt a phased approach to commencing the measures in the Bill in relation to animals. In other words, we will commence the measures in the Bill for only a select group of animal species in the first instance before commencing them in relation to other species. For example, in the first phase it is likely to be animals typically used in agriculture or aquaculture.

As indicated during Committee, we intend to use the commencement powers within the Bill to achieve that. These powers allow us to bring the provisions in the Bill into force in relation to a specific list of species or group of animals; for example, we can apply the provisions to cattle by stating the species name as Bos taurus—domestic cows. That means that until the relevant commencement regulations applicable to them are made, some species or groups of animals, such as companion animals, will not be affected by changes in the Bill. Likewise, GMO rules would continue to apply to them if they are produced using precision-breeding technology. Taking this approach allows us to limit the practical effect of the Bill for a time, while retaining the flexibility and durability needed to capture the potential benefits in other species in the future.

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[The Duke of Montrose (Con)]

It is encouraging to think that the Minister would pick one genus of defined animal such as Bos taurus, but how long would it remain the only race being investigated? Moreover, they are only about half of the cattle beasts; there are also all the beasts descended from Bos indicus that occupy tropical areas.

[Lord Benyon (Con)]

I understand the point that my noble friend is making. I cited Bos taurus as perhaps the greatest priority in our minds, but I have also mentioned the benefits that would accrue if we could tackle conditions such as PRRS in pigs. He is right that there are other genuses across farm animal species that we must consider.

As I said, we also intend to produce guidance on the animal marketing authorisation process outlined in the Bill. That will include guidance on the evidence that regulations will require to be submitted alongside the animal welfare declaration by the breeder and, if necessary, more specific guidance relevant to particular species. Through that consideration of evidence and clear guidance, we will ensure that the regulatory system works effectively for different species of animals. I hope that the Government’s intended approach, our commitment to phase the introduction of animals under this legislation and the words that I have said from this Dispatch Box are clear and reassuring for noble Lords. I ask noble Lords to consider not pressing their amendments.

[Baroness Bennett of Manor Castle (GP)]

My Lords, I thank the Minister for his answer. I thank everyone who has participated in, as he said, this fascinating, detailed and high-quality debate.

I will start with the small bombshell that the Minister that just dropped. We appear to have had a new outline for the way in which the Bill is to be implemented presented to us at the final stage of Report on the Floor of the House—and, as the noble Duke, the Duke of Montrose, pointed out, with some very unclear elements where we suddenly appear to be covering half the cattle but not the other half. I question whether this is the way in which we should be making legislation.

I want to raise a point on something the Minister said which has not been raised before: why is aquaculture here? As the noble Lord, Lord Winston, said, the reality of land animals is that at least you can keep control of them and muster them fairly well. If we include aquaculture in the early stages, we have to realise that once you release something into the sea, as we know from farmed salmon, there will of course be escapes. We have not had a chance to debate all the things the Minister just said.

I want to go back to first principles. I return to the immensely powerful and important speech by the noble Lord, Lord Winston. As he said, he has 40 years’ experience of working with genes. He is your Lordships’ House’s absolute expert. The noble Lord said that we are embarking on a massive experiment with potential global repercussions, but we do not understand what we are doing. Before I go further, I want to put those words to the Minister. My understanding is that the precautionary principle is part of government policy. How does this Bill fit with that principle?

[Lord Benyon (Con)]

Let me address some of the points that the noble Baroness has made. The Government have always said that our priority for the rollout of this technology will be plants, then animals. I have added to that the reassurance, in frequent meetings that I have held with noble Lords before today, that we can phase that part of it as well. So I do not consider that to be a bombshell.

ACRE, the body that advises the Government on releases into the environment, has recommended that precision-bred organisms pose no greater risk than their traditionally-bred counterparts. Its advice is supported by the Royal Society, the Royal Society of Biology and the Roslin Institute. As for food and feed, consumer safety will be ensured through a case-by-case assessment by the FSA to ensure that products are safe for consumption.

So I hope the noble Baroness feels that his is not a bombshell, that clear processes are involved and that we have been, in every way, precautionary about how we do this. I put it to her that surely it is being precautionary to tackle some of the problems we face. The greatest challenge ever for humanity is to adapt to climate change and to produce food in a way that a modern society, a civilised society, wants—to make sure we address issues such as animal welfare. That is the opportunity of this Bill.

[Baroness Bennett of Manor Castle (GP)]

I thank the Minister for his answer. I will pick up that point about animal welfare, and indeed pick up the points made by the noble Lord, Lord Krebs, about pigs in the US that have been gene-engineered—or, rather, gene-disrupted— to make them resistant to porcine reproductive and respiratory syndrome.

This is a case of knocking out one gene in these pigs. We know that any given strain of a virus mutates at a rapid rate—we only need to look at Covid-19. Where we have pigs held in the kind of crowded, dangerous conditions in which we know pigs are held in the US, the virus will mutate very quickly. We have been through this many times. We had it with resistance to pesticides: we got rid of a single disease with one gene and then, of course, it goes. This is the way that biology works, as the noble Lord, Lord Winston, said. We hold those pigs in the kind of crowded, dangerous conditions where PRRS is a concern. Let us remember that this genetic change is only against that one disease. When swine flu arrives, there is nothing in those pigs that will protect them against it, or prevent it becoming a zoonosis and crossing the species barrier into humans. Yet we continue those farming practices.

I pick up the point from the Minister and the noble Lord, Lord Taylor of Holbeach, who said that this is the only way we will feed the world and the only way to get more production. That is what we were saying in the 20th century. The discussion on Friday that I referred is only a preprint, but it reflects the direction of the new biology. The noble Lord, Lord Krebs, said that there is a centre of gravity, but we also know there are tipping points. The new biology acknowledges that a wheat plant and every other complex organism is a holobiont; it operates as a complex of what we think of as the plant, bacteria and fungi that work together. The preprint showed that when a wheat crop is dealing with drought, the epigenetic changes—the kind of changes that the noble Lord, Lord Winston, was talking about, where the plant adapts to circumstances and has its genes expressed in different ways—were happening overwhelmingly in the bacteria and fungi. It is not the genetics of the wheat plant at all. I do not accept that this is the way to feed the world, without tackling the issues of poverty, inequality, food waste and feeding perfectly good food to animals. We need good management of soils and crop diversity—that is how we feed the world.

I feel a sense of despair at this point; I have no alternative but to withdraw my amendment with great reluctance. I really hope that your Lordships’ House has listened, particularly to the speech by the noble Lord, Lord Winston, and that the Government listen to this as we go forward from here.

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Moved by

[Lord Benyon]

3: Clause 1, page 1, line 11, leave out from “genome” to end of line 14 and insert “that results from the application of modern biotechnology could have resulted from traditional processes, whether or not in conjunction with selection techniques, alone,”
Member’s explanatory statement
This amendment would limit the test in Clause 1(2)(c) to features of a precision bred organism’s genome that result from the application of modern biotechnology and would require them to be capable of resulting just from traditional processes (whether or not in conjunction with selection techniques).

[Lord Benyon (Con)]

My Lords, I will begin by speaking to the amendments tabled by the noble Lord, Lord Krebs, whom I thank for his amendments and his ongoing support for the Bill. I will come on to the government amendments in due course.

The noble Lord’s amendment highlights some of the challenges in maximising the potential of plant and animal genomes using traditional breeding methods. The crucial issue is whether the types of genetic features under discussion could, in principle, occur in the genome of the organism by traditional processes. In other places in the Bill, where we intended to refer to outcomes that

“could reasonably be expected to result”

from a process, rather than outcomes that could in principle so result, we have expressly said so. This means that it is unnecessary to add further descriptions to the word “could” in Clause 1. Consequently, the existing wording—“could” have resulted from traditional breeding —already achieves the Government’s intended ambition, without the need for further descriptors in the definition. I believe that it achieves the outcome that the noble Lord wants it to.

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[Baroness Bennett of Manor Castle (GP)]

My Lords, having spoken a great deal on the last group, I will be extremely brief now. What we have is the Government still trying to define what the Bill is about at this incredibly late stage. We have been through Committee, Report and the other stages in the other place and here, and here we are still trying to find the wording. Neither the science nor the law is stable enough for this to become an Act and we have just seen a very useful demonstration in this short debate of how this is very likely to be a field day for lawyers, so the lawyers in your Lordships’ House can get ready.

[Lord Benyon (Con)]

My Lords, I thank both noble Lords for their contributions to this debate. I particularly thank the noble Lord, Lord Krebs, for his continuing help in trying to get this right. I hope the eyes of not too many noble Lords glazed over. I had to get on the record, about what is undoubtedly a very technical piece of legislation, what we were seeking to do by the changes that we were putting in.

The noble Lord makes a very good point about “modern biotechnology” as a term. I am at great pains not to throw in new definitions that could one day come back to bite us, but “modern technology” is widely recognised to cover a specific set of technologies for regulatory purposes. In particular, it is used in the UN’s Cartagena Protocol on Biosafety. The definition of modern biotechnology can be updated—to be probably even more modern technology—subject to the affirmative procedure under powers in the Bill if required.

I hope that the government amendments, which aim to clarify which kinds of genetic features are permissible in a precision-bred organism and the techniques by which they may be introduced, will provide assurance to the noble Lord not to press his amendments. I hope that noble Lords are confident in accepting these government amendments.

Amendment 3 agreed.

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Moved by

[Lord Benyon]

5: Clause 1, page 1, line 14, at end insert “and
(d) its genome does not contain any feature that results from the application of any artificial modification technique other than modern biotechnology.”Member’s explanatory statement
This amendment would introduce a new requirement to ensure that the genome of a precision bred organism could not contain features that result from artificial modification techniques that are not modern biotechnology within the meaning of the Bill.

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Moved by

[Lord Benyon]

8: Clause 1, page 2, line 25, at end insert—
“(7A) An “artificial modification technique” means any technique by which genes or other genetic material can be artificially modified within the meaning of Part 6 of the Environmental Protection Act 1990 (as it has effect from time to time).”Member’s explanatory statement
This amendment would define artificial modification techniques in line with Part 6 of the Environmental Protection Act 1990 (which deals with genetically modified organisms).

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[Baroness Hayman of Ullock (Lab)]

My Lords, the noble Baroness, Lady Bennett, has tabled two amendments. Amendment 12 concerns the publicly available register. Clearly, transparency and information for the public will be important if we are to carry people with us, so we need to look at how we develop registers and information to reassure people and to give them the information that they need to have confidence in the legislation.

In Committee, my noble friend Lord Winston and the noble Baroness, Lady Parminter, drew attention to the parallel piece of legislation, the Human Fertilisation and Embryology Act, in which there is a requirement for the surrender of ongoing records containing the information about the impacts, both the positive and the adverse outcomes, on individuals used under the terms of that Act. The noble Lord, Lord Krebs, read out an opinion which emphasised the importance of an audit trail, so there is a general feeling in this House that information and a public register are important.

Amendment 13 is also in the name of the noble Baroness, Lady Bennett. I thank the Delegated Powers and Regulatory Reform Committee for its report on the Bill, which was very helpful. I reassure the Minister, who knows that we support the Bill, that what concerns us is that so much is left to an unknown number of SIs over an unspecified timescale. If the regulations in Clause 3 are under the affirmative procedure, Parliament will rightly have a formal role in improving the finer details of the release and marketing notices, crucially ensuring that we have proper political consensus on this. As the noble Baroness, Lady Bakewell, said, the Government have moved a number of clauses from the negative to the affirmative procedure. I will not go into all the detail, as she covered everything that I was going to ask about on this, since some of it is not crystal clear. We know that the Government can see that there is merit in moving from the negative to affirmative. Can the Minister clarify why not this clause as well if that is not the case, as this is important?

[Lord Benyon (Con)]

My Lords, I thank the noble Baroness, Lady Bennett, for her Amendment 12, which would require details of the specific gene editing event and the whole-genome sequence of a qualifying precision-bred organism to be made publicly available for its release into the environment. The noble Baroness’s Amendment 13 to Clause 3 would require that regulations made under this clause to establish a public register containing this information are subject to the affirmative procedure.

It is not our intention to require breeders to include sequence data as part of their release or marketing notices. I have discussed this previously following an amendment tabled by the noble Lord, Lord Winston, in Committee. We have since had a very useful meeting with the noble Lord and our scientific advisors, ACRE, to explore why whole- genome sequencing information has limited value in most cases, and the noble Lord has not retabled his amendment on Report.

This type of information has limited value because there is a significant degree of genetic variation between individual plants and animals within a species, which is more or less the point that the noble Lord, Lord Krebs, was making. This amount of background noise means that the value in requiring whole-genome sequences is limited in terms of addressing regulatory questions; for example, questions about the precision-bred status of a plant or animal. Additionally, the release notice that researchers are required to submit to Defra will be in line with the requirements of the Genetically Modified Organisms (Deliberate Release) (Amendment) (England) Regulations 2022, which were agreed by the affirmative procedure.

Our intention is that information provided in release notices will be published on the precision breeding register and will include the relevant and necessary information about the precision-bred organism in it. We also intend to require developers to confirm that the organisms that they intend to release in research trials meet the criteria in the Bill. The technical details of this notice will be prescribed by regulations, prepared with input from the advisory committee appointed to advise the Secretary of State on the regulatory status of these organisms and, in accordance with the amendments to Clause 4 that I have tabled, our intention is that such regulations will be scrutinised using the affirmative procedure before they are made.

I hope that this reassures noble Lords and that the noble Baroness, Lady Bennett, is persuaded to withdraw this amendment and not move her additional amendment to Clause 3, which would specify the parliamentary procedure for the delegated power that her substantive amendment would insert.

I always pay particular attention to points raised on secondary legislation by the noble Baroness, Lady Bakewell. As a member of the Secondary Legislation Scrutiny Committee, she is very good at holding me to account on these. I did not quite understand her point about Clause 3 because there are no regulations in Clause 3 and therefore no requirement for it to be affirmative or negative.

We remain of the belief that the matters to be set out in the regulations under the powers in Clauses 4(3) and 6(2) are administrative in nature. However, the Government acknowledge that these provisions are of significant public interest. We have heard this previously in the House and the Delegated Powers and Regulatory Reform Committee has raised this as well. We have considered these matters closely and have decided to change the procedure from negative to affirmative for both powers. These changes will increase the scrutiny when these powers are used to prescribe the information which must be provided to the Secretary of State by a person who wishes to release or market a precision-bred organism. I hope that noble Lords feel that I was serious in Committee when I said that I had listened to them. I hope that they feel that this improves the Bill. Regulations under Clause 4(1)(b) would be administrative in nature, not of significant public interest, and will remain subject to the negative procedure. I hope that this reassures noble Lords.

Amendments 24 and 25 will increase the level of scrutiny when powers are used to prescribe information that must be included in the precision breeding register. The Government acknowledge that these provisions are of significant public interest. We accept noble Lords’ concerns about the level of scrutiny for such provisions. Therefore, we will change the parliamentary procedure from negative to affirmative for the power in Clause 18(1). Regulations under Clause 18(6) regarding the keeping of the register, which is an administrative matter and, again, not of significant public interest, will remain under the negative procedure.

[Lord Winston (Lab)]

My Lords, I thank the Minister for what he has just said, but can he answer this question about whole-genome sequencing?

When we first started genome sequencing, it was laborious, expensive, time-consuming, and so on. It is now a pretty rapid process and can be done without huge expense. Does the Minister not agree that one of the reasons for doing this is not just marketing—because of course there are different issues there, which is how we are addressing this—but the advantage of getting more knowledge about what we are doing? The advantage there would be seeing where things are moving within the organisms that we are trying to edit. That is important as a research tool because, ultimately, we are doing something that—admittedly—we do not fully understand, and this would greatly increase knowledge. Does he feel that this is a relevant point?

[Lord Benyon (Con)]

It is entirely a relevant point, and was much on our minds when we debated some months ago a research measure in secondary legislation to allow the development of plant precision editing but not for it to be taken forward to market. The noble Lord is absolutely right that this is fast-moving and that we therefore need to be clear about how we regulate: that we are regulating a research process and a process to take products to market. Ministers will have to be clear about the intention of the organisation taking that forward. I hope, through the changes that we made, that there will be greater parliamentary scrutiny, that people with real knowledge, particularly in this place, will be able to scrutinise that, and that the Secretary of State of the day will have the best available information about what is being taken forward and why—whether it is just for research. The point made by the noble Lord about the value of research of products that will never go to market, that it is just to understand a particular aspect of genomic sequencing, is crucial.

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Moved by

[Lord Benyon]

14: Clause 4, page 4, line 24, leave out “this section” and insert “subsection (1)(b)”
Member's explanatory statement
This amendment is consequential on the Minister’s next amendment to Clause 4.

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Moved by

[Lord Benyon]

16: Clause 6, page 5, line 31, leave out “negative” and insert “affirmative”
Member's explanatory statement
This amendment would provide for regulations under Clause 6(2) to be subject to the affirmative procedure.

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Moved by

[Lord Benyon]

17: Clause 11, page 8, line 24, at end insert—
“(9A) Regulations under subsection (5) are subject to the affirmative procedure.”Member's explanatory statement
This amendment would provide for regulations under Clause 11(5) to be subject to the affirmative procedure.

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[Lord Benyon (Con)]

My Lords, I thank the noble Baroness, Lady Jones of Whitchurch, for her amendments, to which the noble Baroness, Lady Bakewell of Hardington Mandeville, and—in the case of the first of the amendments—the noble Lord, Lord Cameron of Dillington, have added their names.

The amendments require the animal welfare advisory body, when assessing precision-bred animal marketing authorisation applications, to also consider and report on the notifier’s history of compliance with relevant provisions of the Human Fertilisation and Embryology Act 1990, the Animal Welfare Act 2006 and other legislation it deems relevant. However, the purpose of the animal welfare declaration process is not to vet notifiers themselves, but to assess their applications for marketing authorisations. The role of the welfare advisory body is to use its scientific expertise to evaluate the notifier’s animal welfare declaration. It would not be an appropriate body to assess compliance history.

We expect notifiers, as with any other keepers of animals, to ensure they are in full compliance with all applicable animal welfare laws. The Animal Welfare Act, as mentioned in the noble Baroness’s amendment, will continue to apply to all vertebrate animals subject to precision breeding. Under the Act, it is already an offence either to cause any captive animal unnecessary suffering or to fail to provide for the welfare needs of the animal. Persons found to have committed certain serious offences under the Animal Welfare Act may be disqualified from keeping animals. Such persons would therefore be unable to keep animals that have been precision-bred.

Similarly, other animal welfare legislation provides for appropriate sanctions for non-compliance. For example, notifiers may also be licence holders for research under the Animals (Scientific Procedures) Act, known as ASPA. It is in the interest of such notifiers to ensure that any research involving animals carried out in the UK complies with the requirements of the ASPA licences relating to that research; these licences may be revoked or suspended if their conditions are not complied with.

Furthermore, the Bill provides powers under Clause 15 for regulations to enable the Secretary of State to suspend or revoke a precision-bred animal marketing authorisation if new information about the health or welfare of the animal or, crucially, its qualifying progeny comes to light, or if the notifier fails to comply with a legal requirement to report information about a relevant animal’s health and welfare under Clause 14. Regulations will describe the procedures to be followed when a marketing authorisation is suspended or revoked, and the consequences of such suspension or revocation.

Amendment 21 reflects ones put forward during previous stages, in this House and the other place. We intend to explore these matters further as we develop the technical details underpinning the animal welfare declaration process. The Government agree that safeguarding animal welfare is crucial, and I acknowledge the high level of interest in this topic. That is why, as I mentioned previously, we have commissioned an external research project to gather the evidence required to develop the health and welfare assessment that underpins the declaration process. This will enable us to set out, in regulations and guidance, the information that a notifier must provide to support their declaration that the health and welfare of a precision-bred vertebrate animal is not expected to be adversely affected.

Furthermore, Clause 13 already ensures that the Secretary of State will need to be satisfied with the animal welfare declaration before issuing a marketing authorisation. That is why we do not consider the amendment to be necessary. In addition, as I mentioned before, the power in Clause 25 allows us to set out in regulations what constitutes an adverse effect on health or welfare. This includes any parameters needed for assessing that and could include consideration of any known health and welfare issues in selectively bred animals.

Finally, the welfare declaration and the welfare advisory body’s assessment will be based on the principle that relevant precision-bred animals will need to be kept in conditions which satisfy existing requirements in the Animal Welfare Act 2006 and, where relevant, the Welfare of Farmed Animals (England) Regulations 2007. I fully understand the noble Baroness’s concerns. None the less, existing animal welfare legislation is in place and the Bill is intended to work alongside that to enable responsible innovation.

I will now address Amendments 17, 18 and 26 in my name. It is essential that the animal welfare protections under this Bill command strong public and stakeholder confidence. To that end, we have listened carefully to the points raised by the Opposition and stakeholders about the need for strong animal welfare protections. We understand that noble Lords feel that there should be more opportunity for parliamentary oversight of these vital elements of the legislation. Consequently, we are tabling these amendments so that regulations made under the powers in Clauses 11(5) and 22(3) will need to be debated and actively approved by both Houses of Parliament through the affirmative resolution procedure before they come into effect.

Amendment 17 relates to Clause 11(5). The amendment provides an increased opportunity for parliamentary scrutiny when powers are used to lay out the form and content of the animal welfare declaration and accompanying documents, and the information that must accompany the declaration.

Regulations under Clause 11(9) regarding provisions for an application for a precision-bred marketing authorisation to be made by a person other than the notifier are a technical and administrative matter and not of significant public interest. They will therefore remain subject to negative procedure.

Amendment 26 relates to Clause 22(3). This amendment will provide Parliament with an increased opportunity to scrutinise and debate the body which is to be designated as the animal welfare advisory body, while retaining the flexibility the Bill provides on how the advisory body can be established. We expect there to be strong public interest in the requirements set out in the animal welfare declarations, and we want to come to Parliament with a robust set of proposals informed by expert advice. Indeed, that is why we have already commissioned in Scotland’s Rural College to run an independent research project to set criteria for the animal welfare assessment and the evidence that will be required to accompany it.

The research will involve experts from the Animal Welfare Committee and a wide range of organisations with expertise in animal welfare, genetics and industry practice. This is a growing, innovative sector, and the regulatory system that oversees it is likely to need to evolve over time. Establishing the regulations in secondary legislation subject to the affirmative procedure will allow the Government to ensure that the regulatory system continues to achieve its goals in the long run, while maintaining proportionate parliamentary oversight of its design and future development. I hope noble Lords will be content to accept these amendments.

[Baroness Jones of Whitchurch (Lab)]

My Lords, I should first declare an interest through my involvement at Rothamsted, as in the register. I have tabled Amendments 19, 20 and 21 in this group. They all focus on the welfare advisory body in protecting animal welfare. I am grateful to the noble Baroness, Lady Bakewell, and the noble Lord, Lord Cameron, for their support.

Amendments 19 and 20 would require the welfare advisory body to look beyond the information provided by applicants to ensure that they have a consistent record of meeting animal welfare standards, as set out in previous legislation. Amendment 21 would require the welfare advisory body or the Secretary of State to consider wider health and welfare issues before granting a marketing authorisation. These factors, set out in the new clause, include the direct and indirect effects on the health of the animal or its offspring, whether there might be pain or suffering arising from increased yields or faster growth, and whether the precision-bred traits may result in the animal being kept in worse conditions. These amendments reflect the widespread concern raised in Committee about the consequences for animal welfare of extending precision-breeding techniques from plants to animals, and they also express the concerns of many animal welfare organisations, including the RSPCA and Compassion in World Farming, as well as the report from the Nuffield Council on Bioethics.

As we discussed before, British farming and traditional breeding techniques have not always had a great record on considering animal welfare. Without going back over all the arguments raised in Committee, I will say that there remains a fundamental concern that the genetic editing of animals will be used for the wrong purpose. Once we understand that there could be benefits from improved disease resistance in animals, we need better guarantees that this will not result in animals being kept in more crowded, stressful conditions, which in turn could result in the spread of new and emerging pathogens. Similarly, we need better guarantees that precision-breeding techniques will not be used to speed up selective breeding for fast growth, high yields and large litters, when they have historically caused a great deal of suffering to farm animals, despite the animal welfare legislation already in place.

All these concerns are raised against the backdrop that so much of the detail in this Bill is left to secondary legislation, so we do not know how its provisions will work in practice. I hope the Minister will understand why we are trying to spell out in more detail the specific animal welfare protections in this Bill. I shall make a further point: this is specifically about animal welfare. It is not a criticism of the whole Bill. It is about the specifics and our widespread concern about wanting to get animal welfare protections right.

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[Baroness Hayman of Ullock (Lab)]

My Lords, I welcome the government amendments that move the regulations to the affirmative procedure; they are extremely welcome.

I thank my noble friend Lady Jones of Whitchurch for her thorough introduction to her Amendments 19 to 21. I am sure noble Lords will remember that in Committee I tabled a number of amendments relating to the welfare advisory body, so we are very pleased to see my noble friend Lady Jones tabling similar amendments today. I spoke at length on this issue in Committee, my noble friend has introduced her concerns and we have heard from across the House, so I shall be brief.

Amendment 19 makes it clear that, in addition to considering information submitted by the notifier, the welfare advisory body should satisfy itself that the notifier has a record of acting in a manner that is consistent with research and animal welfare requirements across other Acts of Parliament. That really should be part of the body’s role. We do not want any confusion or different decision-making across different bodies.

I may have this recollection wrong, but I thought that in an earlier meeting a flow chart was mentioned showing how different animal welfare bodies, in Defra and the Home Office, would interact. I had been hoping to receive a copy of that to get some clarification about precedence and how this was all going to work together. It may have gone into my spam folder and I may have missed it, but if the Minister could check on that, that would be very helpful.

Currently, the Bill states that the welfare advisory body has to determine whether in the animal welfare declaration the notifier has paid regard to the risks to an animal. One of my concerns has always been that it is the notifier who is driving the process and is in the driving seat, rather than the welfare advisory body, which is why we were all very concerned about more checks and balances. We know the Bill says that the notifier has to take reasonable steps to assess those risks, but we do not believe that is a strong enough protection for animals in the Bill.

My noble friend’s amendment would mean that the welfare advisory body had to assess the impact on animals where a precision-bred trait was developed, with the aim, as she said, of achieving fast growth, high yields or other increases in productivity. As we have heard, we have seen that too often in traditional breeding methods, so we need to bring in these protections. We have heard many examples of traditional selective breeding producing animals that were highly efficient but this was often at the expense of animal welfare, and we need to ensure that that is not an unfortunate consequence of the Bill. The RSPCA and Compassion in World Farming have raised serious concerns about the lack of safeguards in the Bill to prevent that happening. In addition, the Nuffield Council on Bioethics has drawn our attention to the fact that many of the effects of selective breeding have been unintended.

We agree with our noble friend that it is reasonable that welfare impacts should be assessed here. Without the amendment, it is not clear exactly how that would be part of that process with the advisory body, particularly in relation to other bodies that already exist. So we strongly support my noble friend and believe that her amendments should be in the Bill.

[Lord Benyon (Con)]

My Lords, I am grateful for another useful debate. I assure the noble Baroness that we sent her a copy of my flow chart, so it must have ended up in her spam folder. I hope none of my other correspondence to her will be rejected into the ether. It sets out in five clear steps the process of taking something through to authorisation.

I say to the noble Lord, Lord Cameron, that I am not one of those people who repel all boarders when it comes to amendments; we have actually moved considerably on the scrutiny of the Bill, and we want to ensure that there is as much agreement as possible. I concede that we might have a problem on Amendment 19, but I will come on to that.

I repeat that the welfare declaration and the welfare advisory body’s assessment will be based on the principle that precision-bred relevant animals will need to be kept in conditions that satisfy existing requirements in the Animal Welfare Act 2006 and, where relevant, the Welfare of Farmed Animals (England) Regulations 2007. So existing animal welfare legislation is in place, and the Bill is intended to work alongside it to enable responsible innovation.

An accusation was made, although I cannot remember who by, that this was an enabling Bill and was somehow a forest of Henry VIII clauses. I reject that. It is not a skeleton Bill. We have set out our substantive policy proposals in the Bill and have included appropriate delegated powers to supplement those provisions. Delegated powers serve a valuable purpose and it is always important to assess them in context. Simply counting up the number of powers in a given Bill is not necessarily always meaningful, but I hope we have shifted the balance in terms of those that are affirmative and those that are negative.

There has been talk of belt and braces. I think you can overdo caution in these circumstances, and you can clog up the system. I really feel it would be difficult to accept Amendment 19 as it would pre-empt the Scottish royal college research project. The Bill already outlines a regulatory framework to safeguard animal welfare that goes beyond existing requirements in traditional breeding.

I hope that my words, and the government amendments to increase the degree of parliamentary scrutiny on the animal welfare provisions in the Bill, provide noble Lords with sufficient reassurance not to press their amendments.

Amendment 17 agreed.

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Moved by

[Lord Benyon]

18: Clause 11, page 8, line 25, leave out “this section” and insert “subsection (9)”
Member's explanatory statement
This amendment is consequential on the Minister’s previous amendment to Clause 11.

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[Lord Cameron of Dillington (CB)]

My Lords, I repeat, again, that I am a very strong supporter of this Bill and everything it stands for. However, again, as I have said at every stage and indeed a moment ago on the previous grouping, the one weakness of the Bill is around animal welfare. Anyone reading the Hansard of the passage of this Bill through the Commons will note that it was the greatest concern of MPs too, but they failed to make even a dent in the Government’s protective carapace on this issue.

In Committee, many noble Lords from all sides of the House—myself included—put down amendments to try to minimise the possibility of any genetic change being proposed or implemented that could result in the future suffering or discomfort of, or distress to, animals or their progeny involved in the process. However, none of these amendments was put to the vote. We now have a well-thought-out amendment—or two—which precisely covers the worries that we all had and attempts to avoid them. The Government should think seriously before they reject them.

[Lord Benyon (Con)]

I thank noble Lords for their engagement on this important issue. I am grateful for the meetings that I have had with noble Lords from across the House on this and for them taking the time to share their thoughts with me and with the House on this occasion. I have found it constructive and enlightening.

We recognise that there is a need to safeguard animal welfare in the new regulatory regime; we are all united on this. That is why we are taking a step-by-step approach with regulatory changes for plants first, followed by animals. The measures in this Bill in relation to precision-bred animals will come into force, as I said before, only when safeguards for animal welfare are in place. This will include a monitoring and reporting system for the precision-bred animals once they are placed on the market.

The Bill will give us the ability to place a time-limited and proportionate duty on breeders and developers to monitor for significant health and welfare outcomes in animals that could be linked to their new traits and to report such outcomes to Defra. This monitoring and reporting system will be informed by research that we intend to carry out—which I have already spoken about—to help us identify the specific outcomes that must be reported, as well as appropriate timeframes and numbers of generations that must be monitored for each species or type of animal.

We believe that the powers in the Bill are sufficient to enable us to put this monitoring system in place. Clause 14 sets out that regulations may require the notifier, or any other person specified, to provide information to the Secretary of State about the welfare of the relevant animal and its qualifying progeny. The regulations may set requirements on the information that must be collected, and they allow the Secretary of State to apply reporting requirements in a bespoke manner. This flexibility is essential to ensure that any obligations placed on businesses are proportionate to risk—this is the key point that I hope I may be successful in getting across.

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Moved by

[Lord Benyon]

24: Clause 18, page 13, line 16, at end insert—
“(6A) Regulations under subsection (1) are subject to the affirmative procedure.”Member’s explanatory statement
This amendment would provide for regulations under Clause 18(1) to be subject to the affirmative procedure.

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Moved by

[Lord Benyon]

26: Clause 22, page 15, line 27, leave out “negative” and insert “affirmative”
Member’s explanatory statement
This amendment would provide for regulations under Clause 22(3) to be subject to the affirmative procedure.

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[Baroness Hayman of Ullock (Lab)]

My Lords, I thank the noble Baroness, Lady Bennett of Manor Castle, for her thorough introduction to her amendment. I completely understand why she is bringing it forward. There are areas of the Bill around implementation, oversight and the step-by-step process that we have discussed time and time again that people are still concerned about. The requirement of the amendment for a report to be published that identifies any gaps in scientific evidence is an interesting one. It will be good to hear the Minister’s thoughts on this.

[Lord Benyon (Con)]

My Lords, I thank the noble Baroness, Lady Bennett, for this amendment. I am keen to have a much wider conversation with people. My learning curve has been incredibly steep as I have gone through this—the noble Baroness, Lady Hayman, is nodding as well. It is an area of science which is not understood by an awful lot of people. While I have sought to bring in as many safeguards as possible, there is a continuing job to do for all sorts of parties, not just the Government, to explain the benefits of this technology and the safeguards that the Government are introducing. However, I do not think that a priority setting partnership should be established in or under this Bill.

The Bill places science at its core. ACRE advised that precision-bred organisms pose no greater risk than traditionally-bred counterparts. As I said earlier, its advice is supported by the Royal Society, the Royal Society of Biology, the Roslin Institute and a wealth of peer-reviewed literature. The Royal Society stated that

“these are no more likely to pose a risk to human health or the environment than non-editing derived mutations, which occur spontaneously in each new generation”.

In earlier debates, I have sought to make it clear that if we inserted regulatory measures or language into the Bill that somehow elevated this technology beyond where it is, we risk misleading the public and we have to be really careful about that.

ACRE’s expertise in precision-breeding technologies is considerable, having first advised on them in 2013. We used this as a basis for our intervention in a pivotal European Court of Justice case in 2018 and for our consultation on genetic technologies in 2021.

The Secretary of State will be required to make decisions based on the advice of expert committees. As part of its current role as adviser on genetically modified organisms, ACRE will also advise the Secretary of State on whether an organism is precision bred. A comprehensive understanding of the underlying science is essential for this process and ACRE members have a wealth of experience in the regulation of genetic technologies. Moreover, this Bill will sit alongside existing legislation that deals with human, animal, and environmental health.

I understand the noble Baroness’s reservations. However, where we have identified evidence is incomplete, we have taken steps to address this. The regulations under the Bill will not come forward until the relevant measures are in place, and Parliament will have the opportunity to further scrutinise them.

Genetic Technology (Precision Breeding) Bill

Lord Benyon Excerpts

3rd reading
Wednesday 1st February 2023 Lords Chamber

Moved by

[Lord Benyon]

That the Bill be now read a third time.

[The Minister of State, Department for Environment, Food and Rural Affairs (Lord Benyon) (Con)]

My Lords, I have it in command from His Majesty the King to acquaint the House that His Majesty, having been informed of the purport of the Genetic Technology (Precision Breeding) Bill, has consented to place his interest, so far as it is affected by the Bill, at the disposal of Parliament for the purposes of the Bill.

Motion agreed.

Moved by

[Lord Benyon]

That the Bill do now pass.

[Lord Benyon (Con)]

It is my privilege to move the Third Reading of the Genetic Technology (Precision Breeding) Bill in this House today. As we have discussed in debate, it is essential that we forge ahead with the Bill now to help address the many challenges we are facing across our food system and environment.

During the Bill’s passage through the other place, we saw record-breaking heat and drought and now, as it nears the end of its journey, we are managing the impacts of winter flooding. Precision-breeding technology is one of the tools we can use to develop plants that are more productive, more resilient to extreme weather, and less reliant on fertilisers and pesticides. This technology will help support our farmers to grow and harvest better, improve the health and welfare of animals, and provide healthier and more nutritious foods for consumers.

We have some of the best scientists and research institutes in the world, and we want to encourage this exciting research and translate it into tangible benefits. I recently had the pleasure of visiting Professor Jane Langdale at the University of Oxford, where I learned about her cutting-edge work developing high-yielding rice varieties for smallholder farmers. I heard how you can precision breed drought-resistant varieties. That is exactly the kind of work we want to see. I know that this is happening across the country, including at the John Innes Centre at Rothamsted, the Roslin Institute and many more places. I left Oxford with the warm glow—no doubt some noble Lords might feel that it was naive but I felt it was genuine—one gets from the belief that we have actually done something good here, which will benefit people in not just this country but abroad.

By introducing a more proportionate and science-based regulatory framework, we want to encourage innovation and enable new breeds of plants and animals to be released for field trials and brought to market more easily. We want to encourage this innovation responsibly. Following the Bill’s passage, we will continue to work with experts and other stakeholders to develop measures to safeguard animal welfare before we bring the measures in the Bill into force in relation to animals.

I thank all those who have supported the Bill and those who put it through its paces to ensure it will deliver on its vision of proportionate and safe regulation of precision-breeding technologies. The specialist expertise that the noble Lords, Lord Krebs, Lord Trees, Lord Winston and Lord Cameron of Dillington, have brought to the debates has been invaluable. As we are all aware, this is a scientific policy area with which some of us do not always feel at ease. It was a truly extraordinary experience to hear the level of understanding and knowledge in some of the exchanges. I really thank many noble Lords for their wisdom and for ensuring the appropriate direction of debates.

I also thank noble Lords on the Front Benches for their invaluable contributions. The noble Baroness, Lady Hayman of Ullock, has led well-considered scrutiny, and I thank her for her debate on this legislation. The noble Baroness, Lady Bakewell of Hardington Mandeville, has provided extensive input to these debates, for which I am grateful. I thank other noble Lords from all sides of the House for their interest and engagement, which has undoubtedly improved the Bill. I know that we had some arguments and that not everyone will have been happy with precisely where we ended up, but it was an enormously beneficial experience to have the debates that we did.

Finally, I want to thank the Bill team, who were led by Fiona White, Emily Bowen, Elizabeth Bates and Elena Kimber, and the Bill policy team, parliamentary counsel and the Food Standards Agency, which worked so hard on the Bill. I thank noble Lords for their support and input into these important debates. I beg to move.

[Baroness Bakewell of Hardington Mandeville (LD)]

My Lords, I realise that the Chamber is filling up and getting ready for the next debate, which is very important, but I would like to thank the noble Lord, Lord Benyon, for his good humour, patience and flexibility during the passage of the Bill. I also thank the Bill team for their help in answering our queries, along with the noble Baronesses, Lady Hayman of Ullock and Lady Jones of Whitchurch, and all those on the Labour Benches, including the noble Lord, Lord Winston, who made a very valuable contribution to the Bill.

As the Minister has said, the expertise of the noble Lords, Lord Krebs, Lord Trees and Lord Cameron of Dillington, was absolutely invaluable. I really enjoyed the exchanges across the Chamber on this very technical Bill. I cannot sit down without mentioning the noble Baroness, Lady Bennett of Manor Castle, who also brought a great deal of expertise to it. My noble friend Lady Parminter supported me brilliantly; we could not have got where we are without her, so I thank her for that.

There were excellent cross-party debates and we reached a reasonable conclusion. We did not get everything that we wanted but we got a satisfactory result and I thank the Minister for that.

[Lord Benyon (Con)]

In adding to the noble Baroness’s thanks to noble Lords, I forgot to mention my noble friend Lord Harlech, without whom chaos would have ensued.

[Baroness Bennett of Manor Castle (GP)]

My Lords, I thank the noble Baroness, Lady Bakewell, for her comment and want briefly to pick up one point from the Minister on Report. He gave the assurance

“that I will be open to any suggestions”

for

“a forum or fora for a wider conversation with the public”.—[Official Report, 25/1/23; col. 278.]

I hope the Minister will confirm that; I am hoping to outreach with him in the coming weeks to do that. The Minister did not refer to the fact that the Welsh and Scottish Governments have both rejected the legislative consent Motions for the Bill to apply to their countries. Can he provide any more information on where the Government are going forward with that?

Two things have happened since we finished Report. The European Patent Office has revoked an EU patent for heme proteins in plant-based meat alternatives, an issue which was also the subject of litigation in the US. In Committee, we talked a lot about patent issues. We did not go back to them on Report but that certainly raises lots of those issues from Committee. Finally, since our debate we have had a statement from the Advisory Committee on Novel Foods and Processes on so-called precision-bred organisms. Many people are reaching out to me to say that it does not resolve the issues of labelling and other regulatory issues, so I draw that response to the Minister’s attention.

[Baroness Hayman of Ullock (Lab)]

My Lords, this was at times a very complex and sometimes challenging Bill, particularly for a non-scientist such as myself; I think both the Minister and I were on a steep learning curve. I thank everybody who provided detailed information and support during the course of this Bill. It really was invaluable as we moved through its progress.

I also thank all noble Lords who took part in the debate. A lot of people spent a lot of time going into detail and depth on this, which was really important when you consider its nature. In particular, I would like to thank: my noble friends Lord Winston and Lady Jones of Whitchurch; the noble Lords, Lord Krebs, Lord Trees and Lord Cameron; the noble Baronesses, Lady Bakewell and Lady Parminter, with whom I worked closely, on the Opposition Benches; and the noble Baroness, Lady Bennett. There was a lot of very clear insight and knowledge that came through noble Lords’ contributions on this Bill, which is one of the reasons why this House is so good at improving legislation—I think this Bill really demonstrated that.

I would also like to thank the officials for their time and their patience with me and my many questions. It was very much appreciated from the Opposition Benches. Finally, I thank the Minister for his time and the constructive way he worked with those of us on the Opposition Benches. It is very much appreciated.

[Lord Benyon (Con)]

I thank the noble Baroness for her kind thanks.

To answer the question asked by the noble Baroness, Lady Bennett—and I thank her for her challenge in this debate and this Bill—I am very keen to continue a conversation about how we raise people’s awareness about how this technology can help, or unravel some of the mystery that might surround people who are concerned about it at times. I assure her that will be the case.

On the question of Scotland and Wales, I hope in time they will see what we are doing and the direction in which the EU is moving on this. I hope they will listen to farmers and institutions like the Roslin Institute, Bangor and Aberystwyth universities, and the James Hutton Institute, and understand that this is an area where it is possible to develop technologies and where, if we all work together, Britain can be a leader. With that, I beg to move.

Bill passed and sent to the Commons.