Dementia Research in the UK

Lilian Greenwood Excerpts

Thursday 10th February 2022 Commons Chamber

[Lilian Greenwood (Nottingham South) (Lab)]

I congratulate my hon. Friend the Member for Oldham East and Saddleworth (Debbie Abrahams) on securing and leading today’s important debate, and I have enjoyed all the contributions. I thank her for the work of the all-party parliamentary group on dementia, which she co-chairs, and the excellent report it published last year on dementia research. The report rightly sets out the need for the Government to honour their commitment and bring forward the dementia moonshot funding as soon as possible. The report also sets out some of the key challenges the sector is facing and where that additional funding could be best used. I know that the Government are currently working on a new national dementia strategy, and I hope that the Minister will use the APPG’s report in its development.

I echo the words of my hon. Friend in her opening contribution: dementia is one of the biggest health challenges facing us today. There are currently 900,000 people in the UK living with dementia. In my city, there are already around 2,690 people living with dementia, and that figure is expected to grow to more than 3,800 by 2030. It is one of the consequences of our ageing population. Dementia does not just affect those who have the condition; it also has a profound impact on family, carers and loved ones. Many, if not all of us know someone who is facing the challenges of living with dementia, and we owe it to them and their families to do what we can to make life that bit easier in the future.

As we all know, there is currently no cure for dementia. Finding a cure must be a key aim, but it is not the only one; we must also invest in research to explore how people with dementia can best be treated and cared for. Dementia is a progressive condition, with the symptoms likely to get worse over time. That has severe implications for family members providing care. I take this opportunity to highlight the work of the Centre for Dementia at the University of Nottingham, based in the Institute of Mental Health. It is addressing precisely that issue. The centre’s mission is to improve the lives of people with dementia and their carers through high-quality, useful research, looking at how people with dementia spend their time and what can help them to get the maximum quality from life.

The University of Nottingham is an excellent example of what can be achieved when there is investment in research, and I know from the Alzheimer’s Society, and from what my hon. Friend said, that there are similar programmes in Exeter and Newcastle. She highlighted their centres of excellence. I hope that the Government will work closely with the charitable funders of dementia research and look to replicate those best practice examples. That is very important for improving healthcare, but that investment in research and development, particularly when it is targeted outside of London, can provide real benefits to places such as Nottingham.

Since the pandemic began, we have seen what can be achieved by our life sciences sector when it has the funding, the leadership and the clarity of purpose it needs. The huge advances we have seen in the last decade around dementia research—whether that is the creation of world-leading research institutions, such as the UK Dementia Research Institute, or the vast increase in the number of people attracted to the UK to do dementia research—have all come about because of increased targeted funding and a national strategy to bring together charities, academics and private investors. It is worrying that the state of the UK’s dementia research sector is now at risk. To be honest, it is deeply disappointing that the Government, two years on from their initial promise of a moonshot, have not yet brought forward the funding. When the Minister replies, I hope that he will set out a timetable for when that will be delivered and confirm that the new strategy will be ambitious about what can be achieved.

One point that really struck me when reading my hon. Friend’s report was the impact of the pandemic and the lack of secure funding on researchers. It is clear from the report and researchers’ testimonies that for many of them this is not just a job but a vocation. Not only are they passionate about science, but many also have a personal link to dementia. Their motivation is to find a cure or treatment, or to improve the lives of people living with dementia, but even before the effects of the pandemic, which shut down many labs and prevented people from properly carrying out their work, it is clear that there was a career bottleneck, causing many researchers to leave the field.

There is no shortage of talent among dementia researchers in the UK, but there is a leaky pipeline. New cohorts of doctoral students are often encouraged to enter dementia research without the funding in place to ensure that they can continue and progress into post-doctoral research. Will the Minister tell us what is being done in the upcoming strategy to address that pipeline—to ensure that our talented researchers do not have to move abroad to continue their work or, worse still, leave the field altogether? I know that the Government gave £20 million last year to support charity-funded researchers, but that is far from what was promised; they must do more.

How can we ensure that more people with dementia and their carers can participate in research? As part of the 2020 dementia challenge, the Government set out an ambition for 25% of people living with dementia to be registered with Join Dementia Research, which my hon. Friend mentioned. However, just 2% of people living with dementia in England have registered on the site, despite the policy being written into NHS commissioning guidance and National Institute for Health and Care Excellence guidance. Attracting the world’s best researchers and private investment relies on us as a country being able to show that we can get the right number and right type of participants taking part in research, so what are the Government doing to encourage and enable that? Of course, it is about not just the benefit to the academic research, but the benefit to participants themselves; the report details how being involved in research can provide a sense of empowerment.

My final point today is about prevention. We simply are not doing enough to communicate to the public what every one of us can do to prevent dementia—reducing our risk by keeping ourselves healthy. One of the key slogans about brain health is “healthy heart, healthy brain.” Cardiovascular problems all increase the risk of memory loss, thinking problems and dementia, but it is never too late in life to reduce those risks.

There are 12 modifiable risk factors for dementia, including smoking, alcohol consumption, exposure to pollution and traumatic brain injury. Cutting out or reducing those risk factors can reduce the likelihood of developing dementia, but despite clear research in this area, Alzheimer’s Research UK’s 2018 dementia attitudes monitor showed that just 34% of people thought that they could reduce their risk of developing dementia—far behind the equivalent figures for conditions such as diabetes and heart disease, which were 81% and 77% respectively. If people do not believe that they can do something about it, they will clearly not take the actions that they could. Will the Minister set out what the Government are doing to improve the health information provided to the public? Will that form part of the new national dementia strategy?

In conclusion, it is obvious that we have a wonderful, rich and diverse dementia research sector in the UK. We have passionate, dedicated academics who work tirelessly to improve the life of people with dementia, and of their families and carers. We have clearly come a long way. We have built terrific infrastructure, and have world-leading facilities, but just as dementia does not stop progressing, neither should we. We have to build on this, particularly given the impact that the pandemic has had on the field. We must offer opportunities and support to academics. If we do not, we are at risk of wasting all the great work done over the past decade. We must not allow that to happen, particularly when there are new, exciting developments that will drastically improve the life of people with dementia. As my hon. Friend the Member for Oldham East and Saddleworth said, we have to provide hope. The Government must bring forward a plan for delivering the moonshot funding as soon as possible. I look forward to the Minister giving us some hope when he responds.

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[Andrew Gwynne (Denton and Reddish) (Lab)]

I wholeheartedly thank my hon. Friend the Member for Oldham East and Saddleworth (Debbie Abrahams) for securing this vital debate, and for the work that she does as co-chair of the all-party parliamentary group on dementia. I also thank the Backbench Business Committee for granting the time for the debate. What it lacked in quantity of Members, given that it is the last debate before the recess, it certainly did not lack in quality.

I think there is unanimity on recognising the value of dementia research and on willing the Government to do more. That degree of unanimity is unusual in such an adversarial Chamber as the House of Commons, but we have had a good debate today. I pay tribute not just to my hon. Friend the Member for Oldham East and Saddleworth but to my hon. Friend the Member for Nottingham South (Lilian Greenwood), the right hon. and gallant Member for Beckenham (Bob Stewart), and the hon. Members for Bexhill and Battle (Huw Merriman), for Rutherglen and Hamilton West (Margaret Ferrier), for Strangford (Jim Shannon), and for Coatbridge, Chryston and Bellshill (Steven Bonnar).

Dementia is the only condition out of the 10 conditions with the highest mortality rates for which there is no treatment to prevent, cure or slow its progression. Almost 1 million people are currently living with dementia. Every three minutes, someone develops the condition. As we heard very powerfully from the hon. Member for Ochil and South Perthshire (John Nicolson), it affects not just the individual but those around them—their family and friends. Dementia is also severely underdiagnosed, and that has been further exacerbated by covid-19. There is a backlog of approximately 35,000 people aged 65 and over waiting for dementia diagnoses. I would be grateful if the Minister, in his response, could outline the specific measures that the Government will take to improve early detection of dementia. I also pay tribute to the many charities working on dementia, to the individuals working in research and, as the right hon. Member for Beckenham rightly did, to those caring for people with dementia—not just the professional carers, but the massive army of often family carers looking after their loved ones.

Unless we find a prevention or cure for the disease that causes dementia, the number of people in the UK living with the condition is likely to reach 2 million by 2050—a shocking statistic. As we have heard, dementia and Alzheimer’s disease were the leading cause of death in 2021. As the hon. Member for Bexhill and Battle said, in 2021, we were in the middle of the covid pandemic and rightly focused on the tragic deaths of people from covid-19-related illnesses, but dementia and Alzheimer’s topped the league table. Indeed, in 2019, 15.9% of all recorded female deaths were due to the condition. This is big, and I know that the Minister understands the severity. Those shocking statistics mean that dementia has consistently, for whatever reason, over a long period of time, suffered from under-investment in research.

Great work is being done in my constituency of Denton and Reddish in Greater Manchester, as it is across the United Kingdom. I pay particular thanks to those working in Tameside and Stockport memory services, who give the initial dementia diagnosis, provide individuals with initiating and monitoring medication, and connect them to support groups in their community. That kind of holistic approach to dementia care is crucial.

Dementia can be cured only with research, however, which is why I am also proud of the work that the Greater Manchester dementia research centre is doing in this field. The centre aims to connect people living with dementia to cutting-edge studies and to the National Institute for Health Research. The centre works across the UK through the UK Brain Health Network, which has researchers in Bristol, Edinburgh, London, Cambridge, Oxford, Cardiff and Belfast, and which aims to bring molecular diagnostics into routine practice throughout the country.

Alongside the wider Greater Manchester “Dementia United” strategy, that innovative work gives my constituents who suffer from dementia the research, support and clarity that they deserve. It is just one example of the really good work taking place across the country. We need world-class research to achieve the best quality of life for people and families living with dementia.

The Minister is perhaps one of the nicest people I have to face—other than you, Mr Deputy Speaker—and I know that he genuinely wants to do the right thing, which is good. He knows, however, as has been referred to on numerous occasions, that his Government’s 2019 election manifesto promised to pour £1.6 billion into dementia research over the next decade as part of the so-called dementia moonshot. There has been huge unanimity in the debate that we want to see that happen. That was a point made powerfully by my hon. Friend the Member for Nottingham South. Over two years on from the general election, we have seen no plans to deliver that funding increase. The latest figures show there has actually been a decrease in Government spending on dementia research, with funding down by over £20 million since 2016. It has gone down by £7.2 million per year under this Prime Minister. That is totally unacceptable. I hope that in his response the Minister will address how on earth that has been allowed to happen.

[Lilian Greenwood]

Does my hon. Friend agree that the reduction in Government funding is particularly concerning, because the pandemic has had a devastating impact on the ability of charities to fundraise? Medical research charities, which fund 51% of all medical research in the UK, have seen their ability to fundraise reduced drastically.

[Andrew Gwynne]

My hon. Friend makes a crucial point. There has been a perfect storm. As we have heard, there is a growing list of people waiting to be diagnosed properly with dementia as a consequence of the covid pandemic, and, as she rightly says, the very research groups doing in-depth analysis and research into this disease are largely reliant on charitable sources of funding, which have almost completely dried up over the course of the pandemic.