Question to the Department of Health and Social Care:

To ask His Majesty's Government what assessment they have made of the AlphaMissense model by Google, which uses artificial intelligence to analyse the effects of DNA mutations in causing health conditions.

Genomics England has tested the AlphaMissense model as part of their regular research activities to investigate algorithms that may eventually be used to improve the interpretation of variants for patients with rare diseases or cancer. Many further steps are required before it is clear how this type of algorithm may help expert clinical scientists in the National Health Service to make the best decisions for NHS patients.