Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, whether her Department has commissioned independent research to make a comparative assessment of the effectiveness of using (a) dogs as a second species and (b) new non-animal scientific approaches in toxicological testing.

The use of dogs as a second species in toxicological testing remains an important step in the development of safe new medicines, treatments, technologies, and other chemicals. The use of animals in science is highly regulated, and includes a three-tier system of licensing which licenses each establishment, project, and individual involved in performing regulated procedures involving animals.

Currently, there is no independent research commissioned by the Government, that makes a comparative assessment of the effectiveness of using dogs as a second species and new non-animal scientific approaches in toxicological testing. Instead, the Government’s current approach is to actively support and accelerate advances in biomedical science and technologies to reduce reliance on the use of animals in research and importantly, to avoid some of the scientific limitations of animal models of human diseases. This includes stem cell research, the development of cell culture systems that mimic the function of human organs, imaging, and new computer modelling techniques.

UK Research and Innovation remains strongly committed to supporting the development of techniques that replace, reduce, and refine the use of animals in research (the 3Rs), and provides core funding for the National Centre for Replacement, Refinement and Reduction of Animals in Research (NC3Rs). The NC3Rs works nationally and internationally to drive the uptake of 3Rs technologies and ensure that advances in the 3Rs are reflected in policy, practice, and regulations on animal research.