Medicines and Healthcare Products Regulatory Agency

Luke Evans Excerpts

Thursday 16th January 2025 Commons Chamber

[Dr Luke Evans (Hinckley and Bosworth) (Con)]

I congratulate my right hon. Friend the Member for Tatton (Esther McVey) on securing this debate, and on giving Members from across the House the opportunity to raise issues such as Primodos, breast implants, mesh, SSRIs, vaccines and MMR. As a clinician, I have seen patients who have been affected by all these issues, and I know the heartfelt difficulties that they have faced—not only in what has happened to them, but in trying to resolve the problems. It is a testament to her that she has given the House the chance to debate these issues, and I am not sure that the public have ever paid so much attention to a regulator, even in the financial crisis. The MHRA has suddenly become something that people know.

I often used to explain to patients that a regulator should be like a good referee: we should not see them, but they should be there to hold people to account and know the rules. However, modern refereeing is about more than that. A referee has already met the players beforehand, and speaks to the public about how things work. They help to shape the way in which the rules should be interpreted, allowing us to improve the game.

The hon. Member for Great Yarmouth (Rupert Lowe) asked who regulates the regulators, and the answer is that this House is accountable. That accountability is key.

What are the functions of the MHRA? They are: to ensure that medicines, medical devices and blood components for transfusion meet applicable standards of safety, quality and efficacy; to secure safe supply chains for medicines, medical devices and blood components; to promote international standardisation and harmonisation to ensure the effectiveness and safety of biological medicines; to educate the public and healthcare professionals about the risks and benefits of medicines, medical devices and blood components, leading to safer and more effective use; and to enable the development of innovation and research that benefit public health.

I welcome the MHRA’s new chair, Professor Anthony Harnden, who was appointed at the start of the year. I hope he is listening to this debate, as it will be important for him in setting his priorities. I pay tribute again to my right hon. Friend the Member for Tatton because, whether or not the MHRA knew this debate was happening, I noticed during my research that all the guidance was updated on the MHRA’s website only yesterday. That is testament to the power of this place, even if inadvertently.

The last Government did a lot in this space, particularly focusing on patient safety and access. They introduced new regulations on medical devices, with the classic example being diabetes monitoring, but they also set out to attract innovation. Their reforms have helped to make the UK an attractive market for medical technologies. I am pleased that both sides of the House agree that this is a great place for the UK to find growth.

These developments were based on a consultation-led approach, following the changes we have had since 2021, when there was a consultation on the future regulation of medical devices. This led to a proportionate and phased approach that minimises supply disruptions and supports system readiness.

Under the last Government, a road map for implementation was set out on 9 January 2024. Again, I am pleased to see that the current Government updated the road map in December. This has the regulatory aims of adapting new technologies, strengthening patient safety and providing clarity for manufacturers that are trying to bring products to market.

All these significant changes try to balance medical technology advances, market capture, patient access, affordability and clinical outcomes. However, as we have heard in this debate, this is all well and good, but “perception versus reality” comes to mind. We arguably have one of the best regulatory regimes in the world and, post Brexit, there is a real opportunity to lead the way. Counter to what the Lib Dem spokesperson, the hon. Member for Mid Sussex (Alison Bennett), said, it is because of Brexit that we were able to regulate around our vaccines.

As has been said today, there are still serious concerns about the system, surveillance and resources, given the medical tech boom. This is a wide debate, so I will focus my remarks on three areas: the current medical market, the emerging medical market, and communications with the public, perceptions and beliefs.

When it comes to the system for current medications, we need only consider what we heard earlier about SSRIs, and particularly their impact on sexual dysfunction —I happen to have that casework on my desk at the moment. Do the Government believe that the yellow card system works, or will they consider a review?

When it comes to emerging markets, we have to remember that the MHRA has a statutory role not only in regulating but in the advertising and promotion of medicines in the UK. We have seen thousands of online adverts for weight-loss injections, such as Ozempic. The Times found approximately 6,500 adverts that mention GLP-1 on Meta’s ad library between January 2022 and the end of June 2024. And Sky has reported that, according to Simple Online Pharmacy, which has access to wholesale figures, 500,000 people in the UK are currently using things like Wegovy.

I would be grateful if the Government could set out what support they are offering the MHRA to ensure that it can fulfil its roles and functions properly, given that it has to manage promotion, safety and supply in all these areas. Are there any plans to review whether the MHRA is able to meet these conditions in a changing medical world?

Finally, and most importantly, if I were to be critical of the MHRA, I would say that the key thing missing on the list of objectives, as set out by the new chair, is communication. Let me finish where I started: a regulator has never been more in the public eye. As a clinician, I know how difficult it is to wade through complex medical data that is both conflicting and opaque. As my right hon. Friend the Member for Tatton pointed out, freedom of information requests and transparency are key to our understanding of this area. Will the Government look to review how the MHRA interacts with the public, how it communicates with grassroots professionals, and what it can do to explain the hugely important work that it does?

To conclude, as my hon. Friend the Member for Christchurch (Sir Christopher Chope) and the hon. Member for Dewsbury and Batley (Iqbal Mohamed) pointed out, this is all about trust. I think it was Reagan who said, “Trust, but verify”. That seems particularly apt for this debate—for that is the role of a regulator, but it is also the role of the Government and the public. We must build a regulatory system that all can trust, and do so inherently, but that is also easily verifiable at any point. If we can achieve that, we can build a trusted ecosystem that is good for innovation, good for the economy, and, most importantly, good for the people.