Genetic Technology (Precision Breeding) Bill (Fifth sitting)

Kate Green Excerpts

Tuesday 5th July 2022 Public Bill Committees

[Jo Churchill]

Amendment 1 would exclude from the definition of a precision bred organism any organism that has contained transgenic material during any step of its development. I thank the hon. Member for the amendment, but do not feel that it follows the best scientific advice and evidence and would undermine the purpose of the Bill.

It is important that we follow scientific advice and regulate based on the nature of genetic changes made to organisms, rather than on techniques used to develop them. The scientific advice is clear: if an organism contains genetic changes that could have occurred naturally or by traditional breeding methods, that does not present a greater risk than a traditionally bred counterpart, irrespective of the techniques used to develop it.

No precision bred organism will contain transgenes. Some of its ancestors may have contained them, but those transgenes must have been removed for the organism to be classified as precision bred. That is laid out in the Bill.

The transgenic intermediate stages are important, as they enable the precise changes to be made to the DNA of organisms. The transgenes themselves are then subsequently removed. For example, CRISPR-Cas9 DNA would need to be taken out of precision bred animals and plants.

During the evidence sessions, we heard from Professor Nigel Halford of Rothamsted Research. He is using that approach to develop low-acrylamide wheat—a wheat that can provide public health benefits, as well as broader benefits.

[Kate Green (Stretford and Urmston) (Lab)]

I apologise to the Committee for displaying my ignorance, but I am interested in the Minister’s comments about the potential ancestry of genes’ genetic material, which would then have been removed by the end of process. Does that happen in nature?

[Jo Churchill]

It has to go through the regulatory framework to be defined as precision bred, to ensure that any of those precise changes are changes that could have occurred in nature, because we are describing what would happen in nature.

[Jo Churchill]

I thank my hon. Friend.

[Kate Green]

Is the Minister therefore saying that it is not possible to determine whether the way in which genetic material may have moved in and out will replicate what could have happened in nature, but only that the outcome will replicate what could have happened in nature?

[Jo Churchill]

Yes.

[Kate Green]

I think that worries some people.

[Jo Churchill]

During the evidence sessions, we heard from Professor Halford and Professor John Napier, who is developing camelina crops that are high in healthy oils. In both examples that they cited, transgenic DNA introduced during the gene editing process was removed. Under the amendment, both of those examples would fall outside the scope of the Bill, and the plants would be classed as genetically modified organisms, but they are not, because they do not contain any transgenes that are actually part of the process The hon. Member for Cambridge referred to the fact that we can have these little bits of DNA left over in ourselves from viruses and so forth.

We must make sure that we understand what we are looking at. We heard very clearly from Professors Halford and Napier that the techniques are more targeted and therefore very precise, known changes can be made. Therefore we know what we are looking at, and this is stepwise procedure. Some of the narrative infers that the Bill will be passed, and then, tomorrow, the changes will happen. It is not like that; we are talking about the development of science and ensuring that the regulatory framework that we have been working under from 30 years ago, which has been recognised virtually across the world as inadequate, is changed, so that we can keep up with the science.

If we accepted the amendment, it would make the Bill irrelevant. Countries elsewhere with proportionate regulations would be able to exploit the huge potential of the technology as it develops, whereas we would remain impeded by the current legislation. I urge hon. Member for Cambridge to withdraw the amendment relating to the definition of precision bred organisms, although I think he said that he intended to push it to a vote.

--- Later in debate ---

[Daniel Zeichner]

I hope everyone is still with us, because this is not simple. Part of the problem is that we are learning more all the time. We are trying to set out a regulatory framework and structure that will stand a reasonable test of time. The Minister is slightly unfair with her dramatic language of how we are shackled. Different Administrations across the world take different approaches, of which there is a whole range therefore, which suggests that the choice is not a simple binary one between doing this or that. The reason people do things differently is that people are more or less cautious. Part of the debate—the question—is where we want to be on that spectrum, and where we think we will be best placed to attract investment and to give people confidence and certainty about the approach we are taking.

I am still worried, because two almost-parallel things seem to be going on. On the one hand, there is an appreciation that the newer technologies absolutely involve transgenesis, even though the Government and others have been pretty clear in reassuring people that that is not what is going on. On the other hand, the fall-back is then, “Well, that could have occurred naturally,” which is absolutely right, as has been explained to me—nature does that anyway. However, for the legislation proposed in the Bill, does that mean we should not be explicit about reassuring people that transgenesis is excluded? By stating that as we have proposed in the amendment, people get that absolute confidence.

[Kate Green]

I have listened to the Minister and to the scientific explanation of the hon. Member for South Ribble—which was much appreciated. Does my hon. Friend agree that that transparency should extend, from the public perspective, not just to the end product, as it were, but to what will have happened at every stage of the process?

[Daniel Zeichner]

I rather agree. The problem is that although we are spending time and effort to understand this, that does not always get translated into the wider world. We have seen before how this issue cannot necessarily always be explained as carefully as it might be to the wider world, which is why it is so important that we do not leave uncertainty or doubt in the Bill. That is why this stronger amendment would give us that clarity to reassure people, because that is what they want to hear—people are concerned. We will therefore press the amendment to a vote, because it would give clarity.

Question put, That the amendment be made.