Childhood Cancers: Research

Debate between David Mundell and Tonia Antoniazzi

Monday 7th December 2020 Westminster Hall

[Tonia Antoniazzi (Gower) (Lab)]

I beg to move,

That this House has considered e-petition 300027, relating to research into childhood cancers.

It is a pleasure to serve under your chairship, Mr Mundell, and an honour to lead for the Petitions Committee in this debate. I welcome the large number of colleagues who have put in to speak today, and pay tribute to those who are unable to do so due to the parliamentary covid restrictions. As chair of the all-party parliamentary group on cancer, I really wanted to lead on this petition, as it is one that has touched many parliamentarians and their constituents. Indeed, I was approached by the hon. Member for Calder Valley (Craig Whittaker), who is unable to participate today, who asked me to pay tribute to his constituents Julia and Darren, who lost their beautiful daughter Fifi to childhood cancer. I put on record my heartfelt thanks to the petitioner, Fiona Govan, who lost her grandson Logan to a type of brain cancer called diffuse intrinsic pontine glioma, and to Amanda Mifsud from the charity Abbie’s Army, which was set up following the death of six-year-old Abbie from DIPG in 2011.

Children’s cancers represent under 2% of all UK cancers. Despite this low number, that still means that over 500 children die from cancer each year. It is the most common cause of death in children. The great news is that since the 1970s, mortality has decreased by around 70%, and even with the debilitating side effects of many treatments, that is testament to the achievements of research in saving our children. One caveat to those figures is the massive variation in survival rates by cancer type: 99% survival for retinoblastoma, contrasting with 0% for DIPG. Many forms of cancer affect children, but after speaking to Fiona and Amanda, I am going to concentrate on the disease that took Abbie, Logan and so many others.

DIPG is a highly malignant brain tumour located in the pons, or pontine, area of the brain stem, almost exclusively affecting children. DIPG tumours are one of the most aggressive forms of cancer, and the prognosis for children diagnosed with it is terminal—it has a 0% survival rate. What also struck me was that while there have been huge leaps in the treatment of many other cancers and diseases, nothing can be done to treat DIPG. Neil Armstrong lost his daughter to DIPG in 1962, and since that time there has been no development in treatments, let alone a cure. Thankfully, childhood cancers are rare, but that also means that they do not get the research funding that other cancers attract, and are often seen as too difficult to tackle. As Dr David Walker wrote in The Telegraph in February 2016:

“So-called ‘rare’ cancers are collectively as common as the ‘common’ ones. But the perception that research should be funded according to incidence means that individual rare cancers are doomed forever to receive a fraction of the money.”

As such, the equivalent of a classroom full of children die from DIPG in the UK year after year, while there are no meaningful advances in treatment options and no current UK trials.

What does the petition ask of the Government? Less than 21% of research funding on childhood cancers is provided by the Department of Health and Social Care, and there is little transparency on where the funding goes. To change that, the petitioners want the National Institute for Health Research classification system to include specific cancer types and age data. They also ask for a commitment from the Government on ongoing funding obligations and for a set percentage of other funding to be ring-fenced for research on childhood cancers. We also need to look at reprioritising funding, to make sure that money is being used strategically for actual research—and that it is not spent on infrastructure, as happens at the moment.

We need to take full advantage of the highly accomplished researchers we have in the UK, such as Professor Chris Jones, but they need funding to answer the key scientific questions, such as, how can we do better and how can we help these children? That has been done in other countries. The Australian Government awarded about $9 million in 2019 and 2020 for childhood cancer research, and there have been extraordinary advances in outcomes on some cancers. If we can get that funding, the UK can become a centre of excellence in the field.

Yesterday, Fiona sent me an email with a message from one of the families, who are going through an incredibly hard time with their son Joshua. Josh’s mum, Michelle Beresford-Smart, writes:

“Josh is still with us, but since August has been bedridden and no longer able to communicate. Completely paralysed by the end of September and blind in October and no longer able to swallow. About 10 days ago his breathing changed and this week he was put on a syringe driver. No life, just waiting for the inevitable. Horrendous. Josh… was diagnosed in August 2017 with a tremor in his right hand. The GP told us we were being paranoid! Just a trapped nerve!”

Nine days after the GP appointment, they were in Great Ormond Street Hospital. Michelle writes:

“My son was 15 at diagnosis. He is now 18. But, as you know, there aren’t any options here in the UK. He did radiation and chemo and then we were lucky enough to get him on the ONC201 trial in New York. We last visited in February 2020, then COVID struck and options were taken away.”

These incredible women told me their stories about making a change for other families and their children who will be affected with poise and passion, and today I am speaking up on behalf of all the families who deal with the tragedy of losing a child. I ask the Government to do the right thing and fund research on rare cancers to give future generations a fighting chance.

The majority of fundraising is done by parents and family-led charities. Earlier today, I heard that Alison Caplan, a constituent of the hon. Member for East Renfrewshire (Kirsten Oswald), lost her son Daniel, aged 17, to DIPG last week. He was a bright young lad who had his whole future ahead of him. His funeral is this Friday and the family hope to help other children who are diagnosed with cancer, especially DIPG.

These are people who have lost a child to a horrendous disease, but still they continue to fight for better outcomes for future generations. They deserve to have their voice heard and I am proud to have been able to speak for them today.

[David Mundell (in the Chair)]

To ensure that everyone can make a meaningful contribution, I am imposing a four-minute time limit.

Oral Answers to Questions

Debate between David Mundell and Tonia Antoniazzi

Wednesday 7th March 2018 Commons Chamber

[Tonia Antoniazzi (Gower) (Lab)]

2. What discussions he has had with the Royal Bank of Scotland on the potential effect on local communities of the proposed closure of its branches in Scotland.

[The Secretary of State for Scotland (David Mundell)]

I have met senior RBS management in Scotland to discuss the decision. I made it clear that its plans were disappointing for customers and communities across Scotland, and I urged it to mitigate the impact of closures as comprehensively as possible.

[Tonia Antoniazzi]

Small businesses have already reported in Wales and across the United Kingdom that they are being refused if they try to pay in large sums of cash at the post office, as it presents a security risk and post office workers do not have the time to count such large sums of money. What will the Secretary of State do to ensure that there is no disruption to small businesses or the public as a result of these ill-thought-out closures?

[David Mundell]

I certainly share the hon. Lady’s view that these are ill-thought-out closures, and I am very happy to take the specific point forward. I am sure that colleagues who serve on the Scottish Affairs Committee will also be prepared to put that view to the chief executive of the Royal Bank, who, I am pleased to say, has finally agreed to appear before that Committee.

Oral Answers to Questions

Debate between David Mundell and Tonia Antoniazzi

Wednesday 19th July 2017 Commons Chamber

[Tonia Antoniazzi (Gower) (Lab)]

12. What recent discussions he has had with his Cabinet colleagues on the public sector pay cap.

[The Secretary of State for Scotland (David Mundell)]

I hold regular discussions with my Cabinet colleagues on a wide range of matters of importance to Scotland. The Scottish Government are responsible for Scottish Government pay.

--- Later in debate ---

[David Mundell]

I fully acknowledge the contribution that public sector workers make across the UK, and particularly in Scotland. Of course we will listen carefully when the pay boards make their recommendations.

[Tonia Antoniazzi]

Sixty-six per cent. of public sector workers in Wales, another devolved country, are women, and I suspect that the figure is a lot higher in Scotland. In the light of that, does the Secretary of State not agree that the public sector pay gap is now fundamentally unsustainable and is not only eroding the living standards of women and families but damaging the economy?

[David Mundell]

We are all concerned about the gender pay gap. Some figures released within the last hour by a public sector organisation suggest that there are significant gender pay gap issues at the BBC. I set out my position in my previous answer: it is for the Scottish Government to determine pay for Scottish Government employees, and the Government’s position has also been set out.