Animal Testing

Debate between Chi Onwurah and George Eustice

Monday 19th February 2024 Westminster Hall

[Chi Onwurah]

I thank the hon. Member for her intervention. I was not implying support for a specific type of testing, but making a general point: some have argued in the past that animal testing has been necessary to save human lives, and groups such as Understanding Animal Research argue that currently. Understanding Animal Research also gives the example of Duchenne muscular dystrophy, a lethal childhood disease, as a condition where canine models are effective.

Science and innovation can show the way out of this moral maze. To take the example of testing on dogs, NC3Rs, the UK’s National Centre for the Replacement, Refinement and Reduction of Animals in Research, has established a project to develop a virtual second species—a virtual dog—using historical data. On toxicity testing, the UK-based company XCellR8 has developed the AcutoX test as a humane alternative to the LD50 test, which involves giving increasing doses of toxic substances to groups of animals until 50% of them are killed.

Just this month, Newcells Biotech, a spinout from Newcastle University based in my constituency, raised over £2 million from the North East Fund for its models of the retina, kidney and lung, which are used in drug development and which reduce reliance on animal testing. The chief executive officer, Dr Mike Nicholds, told me:

“Over the last 10 years, advances in stem cell biology, 3-D bioprinting and high-content analytical methods such as transcriptomics have revolutionised our ability to build laboratory mimics of human tissues that can reduce the use of animals in the early stages of drug discovery. Pioneered in academia, these approaches are now established in mainstream biotech and importantly the regulators have moved to increasingly accept these non-animal models as reliable. Innovations such as retinal organoids, produced by Newcells Biotech, are being used globally to support the development of drugs that cure blindness, demonstrating the power of these new alternatives.”

He went on to say:

“While the prospect of fully replacing animal testing is likely to be at least a decade away, that prospect is no longer beyond the horizon and certainly significant reductions in animal testing will be driven through innovation and awareness within this timescale.”

[George Eustice]

The hon. Lady makes an important point. Although these technologies are developing year on year, they have been around for some time. She said 10 years, and some would say that some of them have been around for closer to 20 years. Why does she think we have not seen a corresponding fall in the number of animal tests to date? Does she believe that the current project licensing regime is rigorous enough?

[Chi Onwurah]

The right hon. Gentleman makes a good point, and I thank him for it. In his speech, he talked about some of the challenges around the existing regime. We have seen a huge growth in science, and in biotech specifically, which may, unfortunately, have led to increases in animal testing. But it is also true that the regulatory regime needs to reflect the advances in technology, and I will go on to talk about that.

As well as chips and organoids, we have techniques such as proteogenomics, single-cell sequencing and access to human cell types that we did not previously have. For example, bit.bio, a leading UK cell-coding company, is able to manufacture human neurons that were previously available only through brain surgery. With such advances, I am certain that our brilliant scientists and innovators can help provide workable alternatives to animal testing. Given our country’s strengths in artificial intelligence and data science, Britain can be at the forefront of this scientific revolution, which will make animal testing a thing of the past.

I would, however, like to ask the Minister whether he considers that a priority. Estimates show that NAMs receive as little as 0.2% to 0.6% of UK medical research funding. Being a first mover in this field will bring with it jobs, investment, economic growth and better animal welfare. Will he therefore explain what the Government are doing to support British scientists and to incentivise them to proactively seek to use NAMs in British labs, creating a customer base to pull through new labs?

Before I entered Parliament, I worked for the regulator Ofcom, so I know that regulation can drive innovation and open up competition—or be a barrier to it. Labour is proposing a regulatory innovation office to help ensure that regulation does the former, not the latter. We need to take a proactive approach to ensuring that regulation reflects emerging methods of research if we are to drive forward scientific discovery and trials while reducing animal testing.

With these new technologies, there is a huge opportunity to create new drugs much faster and for less money. Today, in the US, it takes an average of 12 years and $1 billion to create a drug, from initial filing with the FDA to FDA approval. These tools can provide significantly better possible targets for a therapy, reducing time and therefore costs.

Responsive, proactive regulation will help to improve the uptake of new NAMs in accordance with the current regulations’ principles of replacement, thereby eliminating avoidable tests as soon as is practical. That would help to assure the public that their Government are moving in the right direction and doing things proactively.

At the same time, our pro-innovation approach will create opportunities for entrepreneurs and innovators to develop and bring to market new NAMs, with a stable business environment and a path to market. Our ambition is clear, and the views of Members here today are well known. The opportunity is there to support NAMs development, drive the replacement of animal testing and support the welfare of all life—animal and human alike.

That will not happen overnight, and animal testing in human health has long been embedded in our pharma sector. However, we will not advance human therapies and cures, as we should, if we continue to rely on animals that do not get the diseases that humans suffer from.

Food Price Inflation

Debate between Chi Onwurah and George Eustice

Thursday 19th May 2022 Commons Chamber

[George Eustice]

As I said, we recognise that the single biggest driver of pressure on household incomes has been rises in gas and electricity bills. That is why the Government have focused their attention on those areas. My right hon. Friend the Secretary of State for Work and Pensions obviously keeps under open review the approach and the support that we give people, but we should recognise that there are around 1 million job vacancies in this country, with unemployment at the lowest level ever. We want to support people into high-paid work.

[Chi Onwurah (Newcastle upon Tyne Central) (Lab)]

As the campaigner Jack Monroe has highlighted, and as Newcastle’s West End food bank sees in practice, the cruel truth is that the poorer you are, the higher the rate of inflation you face and the fewer choices you have. But the Government have choices, and my constituents are amazed and disgusted at the choices they make to protect windfall profits rather than working people. Why does the Secretary of State think it should be the poorest who pay the price of inflation?

[George Eustice]

I reject the hon. Lady’s caricature. This Government increased the national living wage to £9.50 an hour and have consistently raised tax thresholds so that the poorest do not pay tax at all. This Government and this Chancellor have put in place a package of measures to help those on the lowest incomes.

Oral Answers to Questions

Debate between Chi Onwurah and George Eustice

Thursday 9th December 2021 Commons Chamber

[George Eustice]

I am aware that my hon. Friend lives in a part of the country, and represents a constituency, famous for its ciders. I would be more than happy to meet with her and any of those businesses to discuss any particular concerns that they have, although she will understand that alcohol duties are very much a matter for the Treasury.

[Chi Onwurah (Newcastle upon Tyne Central) (Lab)]

My constituents were horrified to learn just how much sewage is dumped into Newcastle’s waterways during hundreds and hundreds and hundreds of hours each year. Instead of the meaningless progressive reductions that the Government are currently proposing, when will they ban the dumping of sewage so that my constituents can enjoy the glorious River Tyne in all its natural beauty and safety?

[George Eustice]

Earlier this year, we published the direction—the strategic policy plan—for Ofwat, which requires it to prioritise reducing the use of these combined sewer overflows and to secure the funding through the pricing review to deliver that.

Oral Answers to Questions

Debate between Chi Onwurah and George Eustice

Thursday 19th March 2020 Commons Chamber

[The Secretary of State for Environment, Food and Rural Affairs (George Eustice)]

The Government are in close contact with representatives of the food supply chain and with local authorities, including those in the north-east, and also with charities, to ensure that those who need to stay at home will have continued access to food. We have well established ways of working with the food industry during disruption and our retailers already have highly resilient supply chains and are working around the clock to ensure that people have the food and other products that they need.

[Chi Onwurah]

All of us found the images of empty supermarket shelves disturbing, but for those who are vulnerable, aged, unwell, isolated or dependent on food banks, that is causing real fear as to where their next meal is coming from. In the north-east, we have excellent local producers, but much of our food is dependent on supply chains, and I am afraid the Secretary of State’s response will not have given the reassurance required. What specifically is he doing to ensure the supply of food to the supermarket shelves and from the supermarket shelves to people’s homes?

[George Eustice]

It is very important to note that we have significant resilience in our food supply chain, in that food manufacturers are used to coping with increases in demand, not least every year during Christmas. There is not a shortage of food. The challenge we have had is getting food to shelves in time when people have been purchasing more. That is why we have taken steps including setting aside delivery curfews so lorries can run around the clock, and relaxing driver hours to ensure that deliveries can take place more frequently. We are in discussion with Ministry of Housing, Communities and Local Government colleagues about other support that we would deliver locally to get food to those who are self-isolating.

Oral Answers to Questions

Debate between Chi Onwurah and George Eustice

Thursday 6th February 2020 Commons Chamber

[George Eustice]

I very much enjoyed my visit to the seafood village in my hon. Friend’s constituency, and I look forward to visiting that area and Grimsby more generally again in the future. Our fishing industry will have many opportunities as we leave the European Union and depart from relative stability, but for our fish processors in constituencies such as his it is also important that we continue the flow of trade from countries such as Iceland and Norway.

[Chi Onwurah (Newcastle upon Tyne Central) (Lab)]

4. What her policy is on the compliance of imported agricultural goods with UK (a) animal welfare, (b) environmental and (c) food safety standards after the transition period.