Covid-19: Immunology Research

Anum Qaisar Excerpts

Thursday 9th September 2021 Westminster Hall

[Anum Qaisar-Javed (Airdrie and Shotts) (SNP)]

It is a pleasure to serve under your chairship, Dr Huq. I thank the hon. Member for Strangford (Jim Shannon) who secured this important debate. As a relatively new Member, it is my pleasure to have made both my first hybrid Westminster Hall speech and now my first non-hybrid Westminster Hall speech in debates he has secured. While we differ on the constitution, I know the hon. Gentleman makes a valuable contribution to this House, although I have not yet worked out how he manages to be in three places at once. I gently remind him that Scotland is not a region; it is a nation.

I echo the hon. Gentleman in being grateful for the role of immunology and thanking all who are involved in the sector. Without them, this pandemic may have been very different. The pandemic has forced us in many ways to work collaboratively to overcome the challenges put in place by the virus. In our time of need, scientists from an array of disciplines have done exactly that, and have come together to share their expertise, forming our evidence-based approach to tackling the virus.

Specifically, immunology research has played a pivotal role in linking together many of the sciences that have been used to tackle the covid-19 pandemic, such as virology, respiratory science and epidemiology. Although immunology is most known for its role in the development of the vaccine, it also continues to play a crucial role in providing information that helps to form our ongoing public health response to covid-19. Working with partners across the UK and across the globe, Scotland is leading, enabling and delivering world-class covid-19 research, which is a key element of the Scottish Government’s overall response to the pandemic.

Immunologists have worked tremendously hard to ensure that public understanding of covid-19 is as up to date as possible, with University of Glasgow researchers the first in the world to genomically sequence the Kent variant of the virus. Such work by scientists, medical professionals, researchers and a host of others has developed our collective understanding of the virus, its causes and effects, the mitigation strategies, and the vaccine lifeline.

The Scottish Government emphasised research investment early on in the pandemic, which has contributed to global efforts to understand the effects of the virus, to sequence it and to work on vaccine manufacturing and development. As a result, the Scottish Government supported 55 rapid research projects in 15 Scottish universities and research institutions from April 2020, funding contributions to global efforts to combat the virus and its wider effects. Such research has allowed us to tackle the virus with, as I have said, an evidence-based approach.

Being able to deliver the Oxford-AstraZeneca vaccine at such a pace was the product of long-term funding provided by UK Research and Innovation over more than a decade. It was this long-term funding that ensured there was an existing vaccine platform technology, alongside optimised manufacturing methods, as the hon. Member for Strangford referred to. The Oxford-AstraZeneca vaccine development was also facilitated by a £2.6-million UKRI rapid response grant in early 2020. It was this funding that allowed pre-clinical investigations and a phase 1/2 trial to be conducted, as well as the scaling up of the production of the vaccine to 1 million doses by the summer of 2020.

Although the field of immunology is currently most known for its development of vaccines, it is important to note that it plays just as significant a role in contributing to public health information. As we are currently witnessing across the UK, covid-19 is by no means going away any time soon.

In addition, we are yet to understand fully the extent to which it will impact our population in the long term. Approximately 1 million people in the UK have self-reported symptoms of long covid. Of those people, around two thirds have stated that the symptoms have adversely affected their day-to-day activities. The symptoms reported include fatigue, shortness of breath, muscle aches and difficulty concentrating.

The Scottish Government have invested over £400,000 to enable Chest Heart & Stroke Scotland to deliver a long covid support service, which complements the support being provided by NHS Scotland. Along with the Royal College of Occupational Therapists, the Chartered Society of Physiotherapy and the Queen’s Nursing Institute, CHSS recently published a long covid action plan, which calls on the Scottish Government to make a number of changes. Crucially, these changes include a fund to be set up for health boards to establish a local long covid service, although a figure has not yet been set; the removal of bureaucratic barriers in NHS Scotland; and improved data-sharing, so that patients can be spoken to more quickly. Additionally, the document calls for patient care plans to be developed and for medical staff to be trained on long covid, because, CHSS says, some medical staff do not actually recognise it as a real condition.

At First Minister’s questions last week, the First Minister stated publicly that she wanted to discuss the recommendations with the charity in detail, and will give the capacity fund serious consideration in budget discussions.

[Jim Shannon]

I am very impressed and pleased by Scotland’s long covid planning strategy, which the hon. Lady has outlined. However, it is not all about plans. For many families, it is about how they will survive financially—they all want to get better, but they are not sure if that will happen in the timescale they wish. Apart from the benefits system that we have in place, does the hon. Lady have any ideas as to how we could help them financially?

[Dr Rupa Huq (in the Chair)]

On the Clerk’s advice, let me gently remind the hon. Member that, as we are talking about the Westminster Parliament, she should not stray too much into what goes on in the devolved Parliaments.

[Anum Qaisar-Javed]

I do not know off the top of my head, so I will get back to the hon. Gentleman on that matter.

In light of the statistics and the current rates of covid-19, it is crucial that there is continued investment in immunology research, which will allow us to develop an ongoing public health strategy to minimise and manage the impact of the virus on our population. Thanks to the production of the vaccine, when compared to those who are unvaccinated, those who are double vaccinated are at less risk not only of catching the virus, but of an infection turning into long covid.

Furthermore, it has been found that two doses of the Pfizer or Oxford-AstraZeneca vaccine are 96% and 92% effective against hospitalisation with the delta variant, respectively. While the delta variant is prevalent throughout the country, it is reassuring to know that because of the work of immunologists, our population is trying to live life as normally as possible. The vaccine produced by immunologists has both literally and figuratively provided us with a lifeline—without their work, our economy would remain at a standstill.

Despite the steps we have taken in the battle against covid-19, there is still so much we do not fully understand. By continuing to fund immunology research, population-based studies—a key strength of UK research—can continue to provide us with this knowledge. For example, the National Institute for Health Research has played a major role in bringing academic research together with clinical services during the pandemic, ensuring that we learn as we go. It is this continual production of real-time information about covid-19 that will allow us to overcome and stay ahead of the virus and its long-term impacts.

I therefore ask that the UK Government follow the lead of the Scottish Government’s actions and continue to invest in immunology research and ensure the necessary investment in England’s NHS. It is through further investment in this research that we will get the pandemic under control. In turn, this will ensure that the country is far better prepared for any future outbreaks of emerging diseases. Immunology research has undoubtedly played a pivotal role in our overcoming the pandemic, and it will continue to form the foundation of our public health response and our knowledge of the ever-changing landscape of the pandemic.