Hormone Pregnancy Tests

Allan Dorans Excerpts

Thursday 7th September 2023 Commons Chamber

[Allan Dorans (Ayr, Carrick and Cumnock) (SNP)]

There is considerable evidence indicating that those women who took the drug Primodos—prescribed by their general practitioner—and who were pregnant at that time gave birth to babies with serious birth defects, including deformities and disabilities, missing limbs, cleft palates, brain damage and damage to internal organs. In some cases, those women miscarried or had stillbirths.

[Sir Mike Penning]

This is a really important point: Primodos was not prescribed; no prescription was written. No pharmacist could look at the patient and say, “Is this the right drug for that person?” It was a drawer opened, tablets taken out and pushed across. I know it is not intentional, but the word “prescription” is slightly misleading.

[Allan Dorans]

I thank the right hon. Member for his intervention; he is absolutely correct. The surviving victims are now mainly in their 40s and 50s. Many face a host of new medical problems and their bodies continue to suffer. Many have died prematurely.

[Peter Dowd]

The Public Authorities (Accountability) Bill—the Hillsborough law—would require public authorities to admit responsibility following adverse and mass casualty incidents. Some 97 people died as a result of Hillsborough, and a scandalous cover-up went on for decades. Would the hon. Gentleman agree with me, my constituents in the Gallery and other constituents in the Gallery, that it is time to end the cover-up and to establish how many people have died prematurely as a result of Primodos?

[Allan Dorans]

I would welcome that type of inquiry and the opportunity to view the outcome.

Despite serious concerns being expressed by the eminent paediatrician, Dr Isabel Gal, in 1967 indicating the possible dangers of Primodos, no official warnings were issued about these drugs until eight years later. There is strong and compelling evidence of systematic regulatory failures, demonstrating that the committees tasked with safeguarding the health of pregnant women failed in their duty of care.

When I was elected in 2019, I had never heard of the drug Primodos, and I suspect that is the case for many Members. I had heard of thalidomide, as it received far greater coverage in the media at the time. However, since then I have learned much about the horrors caused by Primodos—the devastating effect it had on unborn babies and on the babies born with horrendous birth defects, and the continuing, unimaginable tragic consequences for the mothers and families whose lives have been so cruelly affected by the drug. It is an absolute disgrace and shameful that those families have not only been utterly abandoned and ignored by the drugs companies responsible, but also by successive Governments, who actively put up barriers to avoid accepting the consequences of the manufacture, approval, prescribing and giving out of Primodos.

The drugs companies involved in the production of Primodos, the medical authorities at the time who failed to protect people and successive Governments are all liable for the suffering caused to the victims of Primodos. They are all culpable and guilty of negligence, for failing to put right this horrendous wrong put upon innocent people. It cannot be right that the fight for justice in these circumstances has been left in the hands of a few determined individuals battling against a huge global pharmaceutical conglomerate with millions of pounds of resources and our own Government.

I highlight the case of my constituent, Nan. I have her permission to share her experience and the effect that Primodos had on her and her daughter, Michelle. In January 1975, Nan was a recently married, healthy young woman. Feeling sick and suspecting she may be pregnant, she went to her GP for a pregnancy test, expecting—as was normal at that time—a urine test. Instead, her doctor gave her two Primodos tablets. By 1975, Primodos had already been banned for use as a pregnancy test for five years in Norway and Sweden. Nan put her utmost trust in the knowledge, experience and expertise of her GP. It was subsequently confirmed that she was about seven or eight weeks pregnant. She had a very uneventful pregnancy during which she neither smoked nor drank alcohol.

On 28 August 1975, Nan’s daughter, Michelle, was born. It was immediately discovered that Michelle was born with a hole in her diaphragm, which had allowed her bowel and spleen and part of her liver and kidney to be forced in to her chest cavity, crushing her lung. She was not expected to live, but through the exceptional skills of our national health service she survived and is now 48 years of age. Throughout her life, she has endured numerous operations and surgeries and long periods of hospitalisation. She has suffered severe health issues, including breathing difficulties, a weakened immune system, numerous bowel obstructions and inflammatory bowel infections, and she has been unable to conceive children. The horrendous effects of the debilitating physical, psychological and medical conditions and the extremely challenging health conditions suffered by Michelle and her parents for the past 48 years just cannot be adequately described by me with words.

When Michelle was born in 1975, Nan was unaware that the drug that she had been given to test for pregnancy had been associated with birth defects for the previous eight years. It was not until some two and a half years later that she read an article in the press that reported on a number of cases linking birth defects to Primodos, including internal organ damage similar to that suffered by Michelle. Since that time, Nan, along with many other women, has been fighting the injustice, where no one has ever been held responsible for the damage caused to so many lives through prescribing Primodos, which had been approved by the Government.

In February 2018, the then Prime Minister, the right hon. Member for Maidenhead (Mrs May), announced that Baroness Cumberlege would oversee an independent medicines and medical devices safety review. This review was, among other things, instructed to consider the consequences of Primodos. One of the conclusions in the report by Baroness Cumberlege is that Primodos should have been withdrawn from the market in 1967, after the first report by Dr Gal. However, the Government refused to accept responsibility for the effects of Primodos without a proven causal association, but admitted later, in a Sky TV interview, that there was a possible association. There was a moral duty for Government representatives on the Committee on Safety of Medicines to protect patients, but they failed in their duty of care by suppressing the evidence of harm caused by the drug. Even today, the Government continue to deny that they suppressed evidence, while supporting the flawed conclusions of the 2017 expert working group.

The damage to individuals, lives and families caused by Primodos, successive Governments’ lack of action and the failure to prevent, is immeasurable. This could be a far greater tragedy than thalidomide. Apart from frustration at the pharmaceutical companies and the glacial pace of Government in righting this tragic, historical wrong, the most chilling words we hear, increasingly regularly, are: “We have recently lost another of our Primodos family.” The tragedy is that we all know that those people died without receiving the justice they deserved. Even if compensation were paid, it would never fully compensate the families who were so tragically affected, or take away the immense guilt experienced by mothers who feel that they were in some way to blame for the defects that their children suffered.

It is well past the time for the current Government to put right this historical wrong, end the scandal and give some security to those who have suffered so much, thus allowing the mothers, fathers and the children who have survived some dignity and compensation for the tragedy that was caused through no fault of their own. The very least the Government can do is accept responsibility for the tragic circumstances, immediately issue a full apology to everyone affected by Primodos and compensate the victims. I and my party urge the Government to accept and commit to implementing the full recommendations of the Independent Medicines and Medical Devices Safety review and to set up a redress fund for families affected by Primodos.

[Mr Deputy Speaker (Mr Nigel Evans)]

When we get to the winding-up speeches, it will be six minutes, eight minutes, eight minutes and then we will leave two minutes for the proposer of the motion.