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Arms Length Body Publication (In consultation)
NICE

Jan. 31 2025

Source Page: Early and locally advanced breast cancer: diagnosis and management - Neoadjuvant chemotherapy and ovarian function suppression (update)
Publication Type: Declaration of interests
Document: Register of interests PDF 455 KB (webpage)

Found: Breast cancer (neoadjuvant & OFS): advisory committee – interests register 1 of 16 Breast


Lords Chamber
National Cancer Plan - Mon 10 Feb 2025
Department of Health and Social Care

Mentions:
1: None support bereaved families and drive vital research in this area—Macmillan, Cancer Research UK, Cancer52 - Speech Link
2: None As Cancer Research UK pointed out in its submission to the investigation, the 62-day target for referral - Speech Link
3: None Cancer Research UK has forecast half a million cancer cases each year by 2040. - Speech Link
4: None , world-leading trial to transform breast cancer care through artificial intelligence. - Speech Link
5: Lord Trefgarne (Con - Excepted Hereditary) I lost my wife of 55 years in April last year due to breast cancer. - Speech Link


Written Question
Breast Cancer: Hormone Treatments
Monday 20th January 2025

Asked by: Sharon Hodgson (Labour - Washington and Gateshead South)

Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, what information his Department holds on whether there are ongoing trials to assess whether continuing hormone therapy indefinitely after a primary breast cancer diagnosis would prevent this cohort of patients from going on to develop secondary breast cancer.

Answered by Andrew Gwynne

Research is crucial in tackling cancer, which is why the Department invests over £1.5 billion per year in health research through the National Institute for Health and Care Research (NIHR). NIHR research expenditure for all cancers was £133 million in 2023/24. Cancer is a major area of NIHR spend, reflecting its high priority. The NIHR has commissioned three current studies relevant to this issue, specifically:

  • Improving outcomeS for Women diagnosed with early breast cancer through adhErence to adjuvant Endocrine Therapy (SWEET);
  • Medication brand changes in hormone therapy for breast cancer. A community pharmacy intervention development to improve patients’ adherence and quality of life. ENABLE; and
  • POSNOC - POsitive Sentinel NOde: adjuvant therapy alone versus adjuvant therapy plus Clearance or axillary radiotherapy: A randomised controlled trial of axillary treatment in women with early stage breast cancer who have metastases in one or two sentinel nodes.


The NIHR's Biomedical Research Centres (BRCs) are networks of experts that work collaboratively between the National Health Service and internationally renowned universities. They facilitate early-stage experimental medicine research and support the translation of scientific discoveries. The BRCs are currently supporting a further two relevant studies:

  • Supporting Women With Adherence To Hormone Therapy Following Breast Cancer; and
  • Unirad: Randomized, Double-blind, Multicentre Phase Iii Trial Evaluating The Safety And Benefit Of Adding Everolimus To Adjuvant Hormone Therapy In Women With Poor Prognosis, Er+ And Her2- Primary Breast Cancer Who Remain Free Of Disease After At Least 1 Year Of Adjuvant Hormone Therapy.


The NIHR continues to encourage and welcome funding applications for research into any aspect of human health, including cancer. Applications are subject to peer review and judged in open competition, with awards being made on the basis of the importance of the topic to patients and health and care services, value for money, and scientific quality.


Westminster Hall
Breast Cancer: Younger Women - Tue 12 Nov 2024
Department of Health and Social Care

Mentions:
1: Wera Hobhouse (LD - Bath) cancer than are women over 50.It is truly alarming that in the UK, breast cancer accounts for 43% of - Speech Link
2: Karin Smyth (Lab - Bristol South) The investments we are making now in breast cancer treatment and research are part of our plan to make - Speech Link
3: Karin Smyth (Lab - Bristol South) breast cancer research in the last five years. - Speech Link


Arms Length Body Publication (Published)
NICE

Feb. 19 2025

Source Page: Early and locally advanced breast cancer: diagnosis and management
Publication Type: Stakeholder list updated
Document: Stakeholder list (PDF 57 KB) (webpage)

Found: Page 1 of 4 ‘Early and locally advanced breast cancer: diagnosis and management - Lymphoedema


Arms Length Body Publication (In consultation)
NICE

Jan. 31 2025

Source Page: Early and locally advanced breast cancer: diagnosis and management - Neoadjuvant chemotherapy and ovarian function suppression (update)
Publication Type: Stakeholder list updated
Document: Stakeholder list PDF 140 KB (webpage)

Found: Early and locally advanced breast cancer: diagnosis and management – Neoadjuvant chemotherapy and ovarian


Arms Length Body Publication (Published)
NICE

Apr. 11 2025

Source Page: Early and locally advanced breast cancer: diagnosis and management
Publication Type: Stakeholder list updated
Document: Stakeholder list (PDF 189 KB) (webpage)

Found: BMJ Technology Assessment Group BNMS Bradford District Care Trust Breast Cancer Now Bristol-Myers Squibb


Written Question
Breast Cancer: Diagnosis and Medical Treatments
Monday 2nd December 2024

Asked by: Tanmanjeet Singh Dhesi (Labour - Slough)

Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, what steps he is taking to improve (a) diagnosis times and (b) treatment of invasive lobular breast cancer.

Answered by Andrew Gwynne

We will improve cancer survival rates and hit all National Health Service cancer waiting time targets so no patient waits longer than they should.

Improving early diagnosis of cancer, including breast cancer, is a priority for the Government. There are multiple NHS initiatives and funding streams across the NHS in England that support the early detection of breast cancer, and many organisations across the health service are involved.

The Department spends £1.5 billion each year on research through its research delivery arm, the National Institute for Health and Care Research (NIHR), with cancer the largest area of spend at more than £121.8 million in 2022/23. NIHR spends more on cancer than any other disease group, reflecting its high priority. Our investments in cancer, including lobular breast cancer, are pivotal to informing efforts to improve cancer prevention, treatment, and outcomes.

We are proud to have invested £29 million into the Institute of Cancer Research (ICR) and the Royal Marsden NIHR Biological Research Centre in 2022, supporting their efforts to strengthen research into cancer, including lobular breast cancer. This is complemented by wider investments into breast cancer research including, for example, a £1.3 million project to determine whether an abbreviated form of breast magnetic resonance imaging can detect breast cancers missed by screening through mammography, again including lobular breast cancer.

The NIHR continues to encourage and welcome applications for research into any aspect of human health, including lobular breast cancer. Applications are subject to peer review and judged in open competition, with awards made based on the importance of the topic to patients and health and care services, value for money and scientific quality.


Arms Length Body Publication (Published)
NICE

Feb. 19 2025

Source Page: Early and locally advanced breast cancer: diagnosis and management
Publication Type: Guidance published
Document: Equality and health inequalities assessment (downloadable version) (PDF 190 KB) (webpage)

Found: g) Sex Breast cancer is a disease that mainly affects women.


Arms Length Body Publication (Published)
NICE

Feb. 12 2025

Source Page: Olaparib for treating BRCA mutation-positive HER2-negative advanced breast cancer after chemotherapy
Publication Type: Summary PDF
Document: Download (PDF) (webpage)

Found: Olaparib for treating BRCA mutation-positive HER2-negative advanced breast cancer after chemotherapy