Found: In fact, it is not even possible to prove a causal link because, as with thalidomide, you would have

Found: Alcohol is a teratogen, like thalidomide, and the fetus cannot defend itself. 12.According to SIGN

Found: It does what thalidomide did. It does what some other things do.

Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, whether she plans to take steps to implement recommendations in the report by the APPG on Hormone Pregnancy Test entitled Bitter Pill: Primodos - the forgotten thalidomide, published on 27 February 2024.

Answered by Maria Caulfield - Parliamentary Under Secretary of State (Department for Business and Trade) (Minister for Women)

We remain hugely sympathetic to the families who believe that they have suffered because of using Hormone Pregnancy Tests (HPTs). In 2017 an independent Expert Working Group (EWG) conducted a comprehensive review of the available scientific evidence and concluded that the data did not support a causal association between the use of HPTs, such as Primodos, and adverse pregnancy outcomes. This remains the Government’s position. The Government has committed to reviewing any new evidence related to HPTs and a possible causal association with adverse pregnancy outcomes.

On the recently published recommendations of the HPT All-Party Parliamentary Group, we have no plans to set up an independent review to examine the findings of the EWG. In the interests of transparency, all evidence collected and papers considered by the EWG were published in 2018, along with full minutes of its discussions. Details of conflicts of interests and how these were managed were also published. The Government is reviewing Professor Danielsson’s publication to consider if it presents any new evidence or analyses not already considered by the EWG on HPTs, and will be seeking independent expert advice from the Commission on Human Medicines in due course.

Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, whether she has made an assessment of the potential implications for her Department’s policies of the report by the APPG on Hormone Pregnancy Test entitled Bitter Pill: Primodos - the forgotten thalidomide, published on 27 February 2024.

Answered by Maria Caulfield - Parliamentary Under Secretary of State (Department for Business and Trade) (Minister for Women)

We remain hugely sympathetic to the families who believe that they have suffered due to the use of Hormone Pregnancy Tests (HPTs). In 2017 an independent Expert Working Group conducted a comprehensive review of the available scientific evidence, and concluded that the data did not support a causal association between the use of HPTs, such as Primodos, and adverse pregnancy outcomes. This remains the Government’s position. The Government has committed to reviewing any new evidence related to HPTs, and a possible causal association with adverse pregnancy outcomes.

Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, if she will implement the recommendations in the report by the APPG on Hormone Pregnancy Test entitled Bitter Pill: Primodos - the forgotten thalidomide, published on 27 February 2024.

Answered by Maria Caulfield - Parliamentary Under Secretary of State (Department for Business and Trade) (Minister for Women)

We remain hugely sympathetic to the families who believe that they have suffered due to the use of Hormone Pregnancy Tests (HPTs). In 2017 an independent Expert Working Group conducted a comprehensive review of the available scientific evidence, and concluded that the data did not support a causal association between the use of HPTs, such as Primodos, and adverse pregnancy outcomes. This remains the Government’s position. The Government has committed to reviewing any new evidence related to HPTs, and a possible causal association with adverse pregnancy outcomes.

Found: Thalidomide promotes degradation of SALL4, a transcription factor implic ated in Duane Radial Ray

Found: ICH S5(R3) Guideline 102 Thalidomide CAS No.: 50-35-1 Rat NOAEL Dose Cmax AUC Rat

Found: For example: thalidomide was given to children in the 1960’s, and Chris W hitty is scared of that .