Question to the Department of Health and Social Care:
To ask Her Majesty's Government, further to the Written Answer by Lord Bethell on 5 March (HL1700), what were the mitochondrial DNA mutations in each of the 17 applications considered by the Human Fertilisation and Embryology Authority that have now been approved; and on what dates each application was (1) made, and (2) approved.
The following table shows the gene affected and the mutation in each application, the dates each application was made and approved by the Human Fertilisation and Embryology Authority (HFEA) Statutory Approvals Committee.
HFEA Application reference | Gene affected by mutation | Mutation | Date received | Date approved by the HFEA Statutory Approvals Committee |
M0001 | MT-TK | Details omitted to protect patient identity | 28 June 2017 | 31 August 2017 |
M0002 | MT-TK | Details omitted to protect patient identity | 4 September 2017 | 26 October 2017 |
M0007 | MT-ND1 | m.3460 G>A | 13 March 2018 | 24 May 2018 |
M0003 | MT-TL1 | Details omitted to protect patient identity | 25 September 2017 | 26 July 2018 |
M0005 | MT-TL1 | m.3243 A>G | 5 December 2017 | 26 July 2018 |
M0008 | MT-TL1 | m.3243 A>G | 15 March 2018 | 26 July 2018 |
M0004 | MT-TK | Details omitted to protect patient identity | 4 December 2017 | 30 August 2018 |
M0006 | MT-TS1 | Details omitted to protect patient identity | 9 January 2018 | 30 August 2018 |
M0009 | MT-TI | m.4300 A>G | 28 June 2018 | 27 September 2018 |
M0010 | MT-TI | m.4300 A>G | 11 July 2018 | 27 September 2018 |
M0013 | MT-ND4 | m.11778 G>A | 14 July 2018 | 25 October 2018 |
M0012 | MT-ND1 | m.3460 G>A | 13 July 2018 | 25 October 2018 |
M0014 | MT-ND4 | m.11778 G>A | 23 November 2018 | 31 January 2019 |
M0015 | MT-ND4 | m.11778 G>A | 23 November 2018 | 31 January 2019 |
M0011 | MT-ND4 | m.11778 G>A | 12 July 2018 | 29 August 2019 |
M0016 | MT-TK | m.8344 A>G | 5 July 2019 | 26 September 2019 |
M0017 | MT-ND4 | m.11778 G>A | 22 August 2019 | 31 October 2019 |
Source:
HFEA