Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, what steps he is taking to help develop a dedicated diagnostic pathway for sepsis.

The United Kingdom’s 2024 to 2029 antimicrobial resistance (AMR) national action plan (NAP), published in May 2024, highlights the importance of accurate diagnostic testing to guide effective antibiotic use and tackle antimicrobial resistance. Supporting clinicians to prescribe the right antimicrobials only to those that need them is a core commitment in the NAP. Outcome six of the UK’s AMR NAP specifically relates to supporting the development of diagnostic tests for infection.

NHS England is taking a multifactorial approach to improving the roll out of innovative rapid diagnostics, aligning to the commitments of the 2024 to 2029 AMR NAP. This includes reducing barriers for industry to support the development of diagnostic tests, identifying innovations, and increasing the evidence for putting those innovations into practice.

Sepsis has no specific diagnostic test, and presentation can vary, making it difficult to diagnose. In hospitals, clinicians are supported in recognising sepsis by using the National Early Warning Score, now used in 99% of acute trusts and 100% of ambulance trusts in England. To support clinical staff in primary and secondary care settings, the National Institute of Health and Care Excellence published updated national guidance in March 2024 on sepsis recognition, diagnosis, and early management.