Question to the Home Office:

To ask the Secretary of State for the Home Department, pursuant to the Answer of 14 October 2024 to Question 6246 on Animal Experiments, what harms were experienced by dogs used in research on muscular dystrophy; and how much funding is being provided for human-specific research into that condition.

The Home Office assigns severity classification to protocols in accordance with the Animals (Scientific Procedures) Act 1986 (as amended) which is published at: https://www.legislation.gov.uk/ukpga/1986/14/contents.

The classification takes account of the highest severity likely to be experienced by any animal used in the protocol and takes account of the pain, suffering, distress and lasting harm that an animal is likely to experience, after applying all the appropriate refinement techniques. Of the 21 dogs used for creation and breeding in research on muscular dystrophy, 15 were subject to ‘Mild’ severity and 6 ‘Moderate’ severity.

The Home Office assures that, in every research proposal, animals are replaced with non-animal alternatives wherever possible, the number of animals are reduced to the minimum necessary to achieve the result sought, and that, for those animals which must be used, procedures are refined as much as possible to minimise their suffering.

The Department for Science, Innovation & Technology (DSIT) is leading on plans to accelerate the development, validation and uptake of alternatives to animal testing.