(8 months ago)
Commons ChamberThe House has already legislated to ensure that vapes cannot be sold to people under 18. However, as we are seeing in our local shops, the vaping industry is finding ways of marketing its products that seem designed for younger minds and younger preferences. Once the Bill has been passed, that age limit will be maintained for vaping but, importantly, from January 2027 onwards we will not see the sale of legal cigarettes or tobacco to those aged 18 or less.
My hon. Friend gives me the ideal opportunity to talk about my favourite criminal offence: cheating the public revenue, which is a criminal offence with very settled law. It has a maximum sentence of life imprisonment, and I have deployed it myself against the organised crime gangs to which I referred at the beginning of my speech. A sensible prosecutor will always look at that criminal offence, because it is settled law and good law, and it has a maximum sentence of life imprisonment for those who indulge in it.
I am going to conclude. In fairness, I have been generous with my time.
We want to build a brighter future for our children and grandchildren, which means moving from the tossing sea of cause and theory to the firm ground of result and fact. The result of this legislation will be to free future generations from the tyranny of addiction and ill health. The facts include that parents worry about youth vaping and want us to take on the tobacco and vaping industries. The result and facts of this change will save hundreds of thousands of lives, reduce pressure on our NHS and increase millions of young people’s chances in life. The decisions we make today will stand the test of time. For those many reasons, I commend the Bill to the House.
(1 year ago)
Commons ChamberI am happy to meet my hon. Friend to discuss that specific issue. We are doing a piece of work on a capital survey of all maternity units as well as working with the CQC on how capital infrastructure—beds and so forth—are impacting on maternity performance.
As I said in an earlier response, there is a global shortage of ADHD medication. As we set out in our response to her written question, we expect that to be resolved shortly.
(2 years, 2 months ago)
Westminster HallWestminster Hall is an alternative Chamber for MPs to hold debates, named after the adjoining Westminster Hall.
Each debate is chaired by an MP from the Panel of Chairs, rather than the Speaker or Deputy Speaker. A Government Minister will give the final speech, and no votes may be called on the debate topic.
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I am grateful to the hon. Member for that comment. Given the urgent need—we all agree on that—to protect lives during the pandemic, we also expedited processes by creating RAPID C-19 as a multi-agency initiative made up of the UK’s main healthcare agencies. It was established in 2020, in response to the pandemic, to get treatments, such as Evusheld, to NHS patients quickly and safely. Therefore we did not simply leave the matter in the hands of NICE; we asked RAPID C-19 to review the evidence base for the use of Evusheld and to consider whether the evidence merited patients having access to it ahead of the normal NICE appraisal. The evidence has now been published and is available on gov.uk; any emerging evidence will continue to be kept under review. That includes the Crick data that the hon. Member for St Albans mentioned, which was published in May and in August and is now being reviewed by RAPID C-19, and also the Lancet study that she referenced, which was published on 6 October, relatively recently.
Three types of evidence have been considered. The clinical trial data is generally the strongest source of evidence. However, in this case, the trial was carried out before omicron became dominant, so it does not confirm efficacy for omicron variants. It would be, I think, concerning to deploy a drug on the NHS that had not been considered in the light of omicron.
I will, but given that I have only five minutes remaining to me, this is the last time I will be able to take an intervention.
The Minister is making an interesting speech, but I am really inquisitive as to how we are still using vaccines that have not been tested on omicron, yet we are using the excuse of Evusheld not being tested on omicron for those people who are immunocompromised.
Before we deploy Evusheld on the NHS and give members of the public the sense of security that comes with that, it is clearly sensible for us to investigate its efficacy in the light of the dominant variant. Otherwise, we would be giving people a false sense of security.
We have looked at in vitro neutralisation studies, which can be completed much more rapidly than clinical trials, that have measured in the lab how a new variant changes the binding efficacy of the therapeutic. These studies show reduced binding with different omicron variants, which means that the clinical efficacy against these variants is expected to be reduced. We have also reviewed the published clinical experience of the use of Evusheld, including the studies emerging from the United States and Israel. There can be difficulties in interpreting some observational studies if, for example, there is not an appropriate control group. The conclusion of the evidence review is that there are uncertainties about efficacy, so a clinical trial has been proposed to look at that. We are working with AstraZeneca on the practicalities of creating an urgent trial that can inform the debate ahead of NICE’s ultimate decision in early 2023.
As was noted, other countries have introduced Evusheld, including, in some cases, before omicron was dominant. Many have decided to double the dose to try to counter the drug’s reduced ability to neutralise the omicron variant. Our experts consider that even at this increased dose, the evidence is still insufficient to demonstrate efficacy, so individuals could be at risk if they changed the protective behaviours that they have undertaken for many months.
The Government recognise that an effective pre-exposure programme for immunosuppressed people would be valuable, but the scientific evidence does not support emergency deployment of Evusheld at this time. To boost the evidence base for future decisions, clinical advisers in the expert groups and my Department have recommended a clinical trial, which could help us to answer outstanding questions on dose, efficacy and duration of protection against different variants. We are working through the practicalities of that trial. We will update colleagues and members of the public as quickly as possible.
We have had great success in generating evidence in clinical trials; last week, initial results from the PANORAMIC trial indicated that early treatment with one drug significantly reduced recovery time, and we will now work in the same way to understand what this evidence means for patient access to the drug. I appreciate the difficulties that immunosuppressed individuals face, particularly if they are concerned about not having protection from covid-19 vaccinations, and so continue with behaviours to avoid covid-19. We all recognise the impact that that has on individuals’ lives and want to improve their quality of life. The Antivirals and Therapeutics Taskforce has ensured that UK patients have the earliest access to antiviral, antibody and anti-inflammatory COVID-19 treatments. NHS patients were often the first in the world to receive safe and effective treatment, both in clinical trials and following regulatory approval of treatments.
Colleagues here and those listening at home have my personal assurance that I will continue to work with expert advisers in the Department, and with RAPID C-19, to ensure that they review all emerging evidence, and to ensure that the NICE process is carried out as swiftly as possible, while ensuring that it is safe and efficacious; we want to ensure that members of the public, who may ultimately receive this drug, have confidence that it does what they think it does.
I am holding a meeting for Members of this House with our expert advisers tomorrow at 11 am. It will give Members the opportunity to ask our experts, including those who have been part of RAPID C-19, any questions and seek further assurances. I am grateful to the hon. Member for St Albans for securing this debate, and for the passionate way in which she expressed the strong feelings of members of the public; I hope to work with her productively in the months ahead.
Question put and agreed to.
(2 years, 5 months ago)
Commons ChamberMy hon. Friend makes an important point. As part of our public health messaging and so on, exercise as a preventive mechanism against cancer is extremely important. We have had a call for evidence; we will consider the evidence that has been provided when we look at the 10-year plan, of which exercise will be an important component.
(2 years, 6 months ago)
Commons ChamberI am pleased to give that assurance to my hon. Friend. We are ensuring that every penny is spent on the elective recovery and makes the greatest possible contribution to tackling those covid-19 backlogs. We are investing £8 billion more over the next three years, and that will increase elective activity. I am also pleased to say that in his region, we have already opened some four new community diagnostic centres; just those four have done 60,000 more checks and tests for his constituents.
Following the covid-19 outbreak and the roll-out of vaccines, thousands of immunocompromised people are still shielding, so can the Secretary of State update the House on where we are on delivering Evusheld, which would allow them to have the freedom that we all enjoy?
It is an important question, and the hon. Lady will know that specific guidance is already set out for those who are immunocompromised. As she will also know, Evusheld has conditional marketing authorisation from the independent Medicines and Healthcare products Regulatory Agency. With the MHRA and others, further tests are going on via the UK Health Sciences Authority, because it is essential to ensure that Evusheld works well and satisfies clinicians when it comes to omicron.
(3 years ago)
Commons ChamberMy hon. Friend speaks with great experience, and he is right to ask how the training programme for vaccinators, especially volunteer vaccinators, can be streamlined. That work is going on at urgent speed both within the NHS—within the ICSs—and in support of the fantastic work that St John Ambulance has been doing in this space.
I have asked the Secretary of State on numerous occasions about antibody testing for immunocompromised people. His answer has been about antivirals for when people get covid. Has he looked into giving immunocompromised people antibody tests so that we have a clear picture of who will need the antivirals quickly if they get covid?
My understanding is that antibody tests are available for the immunocompromised and the clinically extremely vulnerable if that is what their consultant believes is necessary.
(3 years ago)
Commons ChamberThe medical rationale is around the incubation period of the virus. Most of the data that we have today is based on previous variants that we have had time to assess. With this particular variant, as my right hon. Friend will know, there has not been enough time so far, but as we learn more, we will change our policies should we need to do so.
Last week, I asked the Vaccines Minister whether the Government would allow immunocompromised people the opportunity to have antibody tests. She helpfully said that she would look into it. Has the Secretary of State discussed that with her, and what are his thoughts on antibody testing for those who do not yet know whether the vaccines work on them?
I believe that, in certain conditions, immunocompromised people can have antibody tests. It is a decision made by their clinicians. I think the hon. Lady is asking whether they can be made available more generally. We are taking expert advice on that. I want to reassure her, on more support for the immunosuppressed, that some of recent treatments that we have recently purchased and that are being authorised by the Medicines and Healthcare Products Regulatory Agency will also provide a much higher degree of support.
(3 years ago)
Commons ChamberWill the Minister give way?
I thank the Minister for giving way. On the point of immunity, many people who are immunosuppressed are extremely worried. I have asked the Secretary of State on several occasions whether he will consider doing antibody testing so that those people have some idea whether they have any protection or they need to adjust things in their working lives.
I have heard the hon. Lady talk about that before and I take the point seriously. It is partly about antibodies and partly about T cells; the science behind it is obviously quite complex. I will take that point away and get back to her.
(3 years ago)
Commons ChamberYes, I am very happy to give that assurance to my hon. Friend. He is absolutely right that this is all about buying a bit of time that our scientists need to assess this variant properly and to determine what it really is and whether we should really be worried about it or not. He is also right to point out that we took measures in the summer removing almost all domestic rules and controls and that they turned out to be absolutely the right measures. Many of my counterparts in Europe now believe they should have taken a similar route, but I remember that all those measures were opposed by the Labour party.
Immuno-compromised people continue to be worried: many still do not know whether the vaccination works on them. The OCTAVE—Observational Cohort Trial-T-cells Antibodies and Vaccine Efficacy in SARS-CoV-2—study showed that around 150,000 people potentially have reduced or no antibody response, but OCTAVE-DUO is not due to report until early next year. Will the Secretary of State ensure that the immunocompromised population has access to antibody tests, thus allowing them to know their level of protection? Will he ensure that those with little or no protection have the support they need to stay safe?
Yes, of course. We want to make sure that we are helping people who are immunosuppressed in every way possible, including with access to any tests that might be clinically required. The hon. Lady may have noted that in the JCVI advice that I referred to, there is a recommendation, which we have accepted, that those who are immunosuppressed and are able to benefit from the vaccine to some extent should be offered a booster dose on top of the third primary dose. The antivirals are also very important for that group of vulnerable people, and it is good that the UK has procured them.
(3 years ago)
Commons ChamberIt is a vital project, and the trust project team are working well with NHS England and with my Department. The scheme, as I understand it, remains on track; like my hon. Friend, I look forward to its completion.
I thank the hon. Lady for her very important question. There is nothing more important than our children. Sadly, some of the actions that were taken at the height of the pandemic, for understandable reasons, have had unintended consequences. That is exactly why we are putting in a record amount of funding, with the biggest catch-up programme for elective procedures in the history of the NHS. I know that that will help.