Scientific and Regulatory Procedures: Use of Dogs

Feryal Clark Excerpts

Monday 28th April 2025 Westminster Hall

[The Parliamentary Under-Secretary of State for Science, Innovation and Technology (Feryal Clark)]

It is a pleasure to serve under your chairmanship, Ms Jardine. I thank my hon. Friend the Member for North Ayrshire and Arran (Irene Campbell) for opening this important debate. I also thank the thousands of petitioners—some of whom are in the Public Gallery, which indicates the strength of public views on this matter—and all hon. Members here today, who have made powerful contributions.

I do not have a dog, so I will not enter the competition about whose dog is the cutest, but I do have two little children who try to touch every single dog we come across when we go around parks; they at least now know that they have to ask permission before they do that. I feel that I am not too far from having one of those cute dogs, or one like Frank, in our household.

The Government fully appreciate that the use of dogs for scientific and regulatory procedures stirs strong emotional feelings for many people across the UK, including myself as a dog lover. In my previous role in local government, I was responsible for environment, including stray dogs, as part of a service for many authorities around us. In a bid to avoid having to put healthy dogs down, we set up London’s first dog hotel, which Peter Egan opened. We had a system where staff could come and take dogs out for walks. Every role I have had has involved looking after dogs, and I must say that I found the preparation for this debate very difficult.

Along with other Members present, I long for the day when we can finally bring an end to animal testing and the use of dogs in scientific research; it cannot come soon enough, but sadly it is not yet here. The UK is world leading in the development of non-animal methods, and the Government are keen to ensure that those are utilised wherever possible. That is why our manifesto commits us to partner with scientists, industry and civil society as we work towards phasing out animal testing. Colleagues mentioned the changes that the FDA has brought forward. To be clear, those bring it in line with us regarding the protection of animals, but where there is new learning to be done, we will absolutely look at that.

As part of our commitment to phasing out the use of animals in science, we will publish a strategy to support the development, validation and uptake of alternative methods. It will set out how we can build on our support by creating a research and innovation system that replaces animal testing with alternative methods wherever possible. However, for now, the carefully regulated use of animals, including dogs, in scientific research remains necessary to protect humans and the wider environment.

I will now expand on why, given the current state of science, we are unfortunately not yet ready to ban the use of dogs for testing and research purposes in the UK. The use of animals in science lies in the intersection of two vital public goods: the benefits to humans, animals and the environment, and the UK’s proud history of support for the highest possible standards of animal welfare.

The balance between these two public goods is reflected in the UK’s robust regulation of the use of animals in science through the Animals (Scientific Procedures) Act 1986, known as ASPA. The Act specifies that animals can be used in science only for specific limited purposes where there are no alternatives, where the number of animals used is the minimum needed to achieve the scientific benefit and where the potential harm to animals is limited to the absolute minimum. As has been mentioned, this is known as the three Rs: replacement, reduction and refinement.

The use of animals in science is therefore highly regulated, including through a three-tier system of licensing, which licenses each establishment, project and individual involved in performing regulated procedures involving animals. All establishments are required to have dedicated individuals, including veterinary surgeons with legal responsibilities for the care and welfare of animals, and an ethical review body that reviews any proposals for the use of animals and promotes the three Rs of animal use.

Our manifesto commitment stands in recognition of the fact that the phasing out of animal testing has to be in lockstep with the development of alternatives. As yet, the reality is that the technology is not advanced enough for alternative methods to completely replace the use of animals. For now, animal testing and research play an important role in supporting the development of new medicines and cutting-edge medical technologies for humans and animals, and it supports the safety and sustainability of our environment.

Animal research has helped us to make life-changing discoveries, from new vaccines and medicines to transplant procedures, anaesthetics and blood transfusions. The development of the covid-19 vaccine, as with all vaccines, was made possible only because of the use of animals in research. Animals are used to assess how potential new medicines affect biological systems, ensuring that drugs are safe and effective before human trials. Many products that would be unsafe or ineffective, or that could cause harm to humans, are detected through animal testing, ensuring the safety of the healthy volunteers who take part in clinical trials, as well as of future patients.

[Seamus Logan]

We have heard from a number of Members today—some of them very learned Members of Parliament who have professional backgrounds in this area—about the serious doubts regarding the efficacy of some of the tests the Minister is referring to. Would she be willing after the debate to share with me the sources she is using to support her claims regarding the value of this testing?

--- Later in debate ---

[Feryal Clark]

I thank the hon. Member for that intervention, and I am happy to share the research and reasons behind my arguments.

For the reasons I have given, animal testing is required by the international agreements followed by all global medicines regulators, including the UK’s Medicines and Healthcare products Regulatory Agency. Although the MHRA does not require all medicines to be tested on two species, safety testing in a second species is required for most drugs, with dogs being one of the species that can be used.

The key proposal in the petition is for an immediate ban on the use of dogs in scientific and regulatory procedures. None of us wants dogs to be used in research, despite how carefully animal welfare is regulated. However, I regret to say that forbidding the use of dogs in medical research—without alternatives at the moment—would likely have catastrophic effects on the UK’s medical research system. We would be unable to meet international regulatory requirements for drug safety testing, preventing virtually all first-in-human trials in the UK and vastly reducing the number of subsequent clinical trials. A significant proportion of basic research would cease, preventing new insight into disease and treatments that save lives and improve people’s health. Forbidding the use of animals in medical research would also likely have a negative impact on animal welfare. Animal testing would move overseas, to countries where the regulations on the use of animals in science are less stringent than they are here.

I am proud to say that the UK is world leading in the development of alternative methods, and we are keen to utilise that technology as much as possible. As much as we can, we are striving to partner with regulators to see how advances in technology can phase out animal use where we are able to do that.

[Ruth Jones]

The Minister is making an interesting speech, because the Labour party manifesto commitment is very clear: we are looking to ban animal testing. We have talked about a road map, which Labour has committed to, so when will that be published and when will the strategy be published? I ask because those are vital things that people in the Public Gallery want to know today.

[Feryal Clark]

My hon. Friend intervenes at the right time, as I was about to say that in publishing our road map, we will be setting out how we can go even further in supporting alternative methods and working towards a world where the use of animals in science is eliminated in all but exceptional circumstances. That will be achieved by creating a research and innovation system that replaces animals with alternatives wherever possible.

Currently, through UKRI, the Government support the development and dissemination of the three Rs. That is achieved primarily through funding for the National Centre for the Replacement, Refinement and Reduction of Animals in Research, which works nationally and internationally to drive the uptake of alternative technologies and to ensure that advances are reflected in policy, practice and regulations on animal research.

[Steve Race]

I failed to catch the Minister’s eye on her previous mention of the three Rs. Does she agree that the number of procedures using specially protected species—cats, dogs, horses and non-human primates—has actually increased over recent years, to about 17,000 from about 15,000 in 2022 and that that was driven by a 38.9% rise in procedures using horses? Does she also agree that our hon. Friend the Minister for Security confirmed that in the period from 1 January 2023 to 30 September 2024, no applications for a project licence under the Animals (Scientific Procedures) Act 1986 were refused? Does she see reductions in the number of animals being used in testing or are they actually increasing as part of the strategy?

[Feryal Clark]

The stats that I have say that in 2023 the use of dogs in procedures reduced by 9%. On overall animal testing, I will have to get back to my hon. Friend. I am sure that my colleagues from the Home Office will be able to explain the stringent licensing process—the procedure that everyone has to go through to be able to obtain a licence.

We want to replace the use of animals in scientific procedures with alternatives where we can. That is why our current approach is to support and fund the development and dissemination of techniques that replace, reduce and refine the use of animals in research, and to ensure that the UK has a robust regulatory system for licensing animal studies and enforcing legal standards, which will drive their uptake. We have a commitment in our manifesto to do all we can to phase out the use of animals—including dogs—in science, and we will be publishing a road map before the end of the year to lay out how we can give increased impetus to the support and validation of alternative methods.

Colleagues asked about ensuring that we are consulting animal welfare organisations, and there is a roundtable meeting with the Office for Life Sciences and animal welfare organisations to do precisely that. The hon. Member for Winchester (Dr Chambers) requested a meeting to discuss issues around the benefits of testing on animals. I am happy to agree to that and will be in contact with his office to arrange one.

I conclude by again thanking Members for their insightful contributions to today’s debate, and I look forward to working together as we go forward.