New Covid Variants: Government Preparedness

Christopher Chope Excerpts

Wednesday 28th June 2023 Commons Chamber

[Neale Hanvey (Kirkcaldy and Cowdenbeath) (Alba)]

I rise to address this Government’s preparedness for new covid-19 variants and other biological threats. Based on past experience, it is fair to say I am yet to be convinced that this Government are making the necessary progress in this regard. I will first address the Government’s culture before moving on to extant concerns specific to pandemic preparedness.

Hindsight is of value only if we are prepared to use the lessons it reveals to ensure that the same mistakes or misjudgments are not repeated. When it comes to calamity and loss, vindication brings only a bitter taste, not solace or comfort. For those of us in this place, and beyond, who voiced genuinely held concerns about the UK Government’s response to the pandemic, yesterday’s evidence to the covid inquiry from the former Health Secretary is unlikely to elicit any sense of schadenfreude—just a deep sense of despair and sadness.

The former Health Secretary’s testimony does not reflect well on those experts who allegedly gave him deeply flawed advice but, ultimately, he accepted that he alone carried ministerial responsibility for the “calamitous state of affairs” not only in his Department but in the agencies that reported to him, as Secretary of State. In short, he admitted that, when courage called, he failed to execute the responsibilities of his office. He is, of course, correct, but his apology rings hollow and does nothing to ameliorate the damage caused.

My abiding memory of the pandemic is the former Health Secretary’s all-too-frequent glib responses from the Dispatch Box to questions intended to be helpful and constructive. I could devote further commentary to his shocking testimony, but I suggest that might be better served by a Privileges Committee inquiry or other serious investigation.

The shutting down of dissenting voices was all too commonplace, and not just in this place. Innova, the beneficiary of lucrative lateral flow test contracts, put pressure on The Scotsman for daring to publish my valid criticism of the reliability of its tests. Despite scrupulously evidencing my assertions, with the support of esteemed academics, the editorial team could not withstand the very deep pockets that Innova had, on the back of billions of pounds of public money spent on its devices.

In addition, pressure was applied to academic and clinical staff who raised concerns about the adequacy of the UK Government’s pandemic response. Although I readily give my thanks to those staff for their ongoing encouragement and support, I am unable to name them, such is my concern that we are not yet out of the woods in terms of truth and reconciliation on these matters. That such a culture was allowed to flourish at a time of grave emergency is detestable.

Although it is clear that the UK Government must change, I see few earnest attempts to do so. I have asked too many questions on these matters to count, and I have led and contributed to multiple debates in this Chamber and in Westminster Hall, but much of that was for naught. Concerns went ignored and commitments were readily discarded, even by those few souls who maintained a position during the ministerial churn from Prime Minister to Prime Minister to Prime Minister. This may seem tangential to the matter at hand, but Government culture is central to organisational learning for future preparedness. In its basic form, the management of any infection is not rocket science, but each strand is necessarily interdependent and must be rigorous in both design and application. The continued failure to understand that fundamental relationship will fatally undermine any strategic future planning.

In essence, robust surveillance and detection should lead to prompt isolation of the threat, followed by the administration of safe and effective treatments, and supported measures, with further screening and surveillance repeated until the threat is managed. Get any step of that process wrong and the risk quickly spirals out of control. Relying on detection and isolation alone will not work. As we know only too well, an over-reliance on vaccination in the absence of robust surveillance is, similarly, a fool’s errand.

A recent briefing from the House of Commons Library set out the ambitions of the UK Health Security Agency and its Centre for Pandemic Preparedness. The CPP aims to ensure the UK’s future pandemic responses are effective and efficient, and that they reduce the negative impacts of health threats. The CCP aims to become the world-leading hub for all aspects of pandemic preparedness. In addition, the briefing notes that the HSA is working in partnership with the United States Centres for Disease Control and Prevention to turbocharge efforts to combat global pandemics and emerging health threats. Those are grand claims, grandiose perhaps, but the question remains: what does this mean in the practice of disease management and control?

In my Adjournment debate on the UK diagnostics industry in May last year, I voiced my concerns about the UK’s lack of preparedness for a future pandemic strategy, whereas economies the world over were developing 10-year strategies for the same. I applaud the efforts of the HSA in conceptualising a detailed report and a tentative timeline to execute a 10-year science strategy. It emphasises transforming surveillance through genomic identification and characterisation of new covid-19 variants, and promoting the use of innovative diagnostics, which are promising steps in the direction I indicated last year.

However, there are still clamant concerns to be addressed on the implementation of this plan and the efficacy of the HSA as an institution to deliver on those ambitions. First, the partnerships section on page 31 of the strategy report that a

“10-year strategic collaboration with Moderna will ensure we are better prepared against future pandemic threats, including through an onshore mRNA Innovation and Technology Centre.”

What is the basis of this “focused partnership” between the HSA and this single specific pharmaceutical company and a single specific vaccine technology? Recalling the Valneva vaccine production debacle and the adverse impact it had on the Scottish based company, may I ask what the rationale is behind such a partnership, as opposed to a more diffuse and cost-effective approach?

During a Westminster Hall debate in January 2022 I raised concerns about the UK Government’s overemphasis on vaccination as the sole plank of their policy, noting that even with the vaccine success delivered by Dame Kate Bingham, they had placed all their eggs in the mRNA basket. That was, and still is, short-sighted. The Valneva vaccine was the only adjuvanted, inactivated, whole-virus vaccine technology, yet the UK Government pulled the contract just before the phase 3 results were published. They demonstrated that the vaccine was highly effective and safe. That makes it abundantly clear that Scotland does have the potential to lead the way for the world in the domain of innovation and vaccine strategy for pandemic preparedness, yet we are continually and systematically impeded by the UK Government in that ambition.

[Sir Christopher Chope (Christchurch) (Con)]

I congratulate the hon. Gentleman on his persistence in trying to hold the Government to account on this subject. He refers to the culture, particularly in the Department of Health and Social Care, of keeping things to themselves, playing cards close to their chest, not having regulatory impact assessments and, in effect, as he says, imposing good ideas on the basis of heroic assumptions that are not being tested. May I encourage him to carry on his good work?

[Neale Hanvey]

I thank the hon. Gentleman for his kind intervention and warm words. I take them in good grace. He makes an important point. Assertations were made throughout the pandemic that things were one way and, despite interrogation, any understanding that they could not possibly be that way was continually denied. That was very frustrating, and I thank him for his encouragement.

In November 2021, Dame Kate Bingham called the decision to cancel the Valneva contract “inexplicable”. Do the UK Government still not get that? Why are they still not listening to the one person who came through the pandemic with their reputation enhanced, because she did the job she was tasked to do and did it well?

The British Society for Immunology has told me that it supports the use of all vaccine technologies where they have proved safe and effective in clinical trials, stating that a broad portfolio of vaccines is important as we move forward in providing protection against future variants. It also notes that mRNA vaccines were deployed first as they were the first vaccines to be approved. However, the Medicines and Healthcare products Regulatory Agency has since approved the use of eight different covid-19 vaccines that utilise a variety of technologies, including mRNA, viral vector, whole virus and protein-based platforms. What is the Government’s strategy to harness the power of all technologies, considering their intended partnership with Moderna?

--- Later in debate ---

[Maria Caulfield]

There are several ways, and I did try to set some of them out. As I said, UKHSA tests samples from covid-positive patients around the country every week and does genomic sequencing to identify new variants or variants of concern.

We are not currently doing international border checks, but we are working with international partners, so should a new variant emerge in another country, we can step up that capability. We introduced border controls on new arrivals a couple of months ago due to the risk of a new variant from China, but that was stepped down because testing showed that there was no risk to the general population. Waste water testing is also still available should it be required, so there is a range of testing capabilities to identify variants of concern and respond quite quickly.

Moving on to vaccines, we are developing mRNA capability, but not just in covid-19 vaccinations. That is one way of delivering covid vaccinations, but that capability is also being used for respiratory illnesses and cancer vaccination trials. There is the potential for that technology to be used in a range of vaccines, not just for covid-19. A range of different vaccines are available, and should a variant of concern or change of variant emerge, we will take advice from the JCVI as to which vaccine is best to use and which group of the population is best to vaccinate. That is an ongoing piece of work.

On some of the hon. Gentleman’s other points, the covid inquiry is obviously ongoing. As the Minister responsible for pandemic preparedness, I am keen to learn the lessons about testing capability, PPE, and vulnerable groups that may need greater protection in future pandemics. But we also need to be live to the fact that a pathogen could emerge that is completely different from covid, flu, or avian flu, which we are also monitoring actively. We need to be nimble in our response to any future pandemic. My concern is that we may just look at covid as the only future threat, but that is absolutely not our policy; we are looking at a wide range of threats, both in the UK and abroad.

[Sir Christopher Chope]

The Minister referred to mRNA technology. Are the Government absolutely convinced that the technology is safe and effective? Are they in danger of putting all their eggs into that particular basket?

[Maria Caulfield]

We are certainly not putting all our eggs in the mRNA basket for covid, or for any other use of mRNA technology. Such vaccines must still pass the MHRA assessment in order to be licensed for use. As mRNA technology develops for other clinical conditions, whether cancer or respiratory illnesses, those vaccines will also have to be awarded a licence by the MHRA. It is not the case that mRNA vaccines are given carte blanche because they have been used in covid; they will have to pass the necessary research hurdles to gain licences for future use. We are certainly not just relying on mRNA for covid—although it has been effective and the technology means that it can react to variants and be altered depending on the variant. We are using other vaccines for covid, and working with other partners. I reassure my hon. Friend on that.

I am very happy to continue updating Members on the progress that we are making and any future booster vaccination programmes for covid-19 that will be running, and to update the House on the work of UKHSA regarding monitoring, surveillance, and future testing capabilities.