(1 year, 5 months ago)
General CommitteesI want to say a few words, because, as the Minister is well aware, I am the MP for South Cambridgeshire, which is the life sciences capital of the UK, with 400 life sciences companies. Some of the feedback I have had about the MHRA suggests that it is under-resourced, so I very much welcome this increase in its resourcing. A lot of companies in my constituency are doing a lot of innovation, and they say that one of the constraints on them is getting their work through the MHRA and its ability to process it. I was glad to hear the Minister say that the regulations will help the MHRA keep up with innovation, hire new staff and so on.
How do we make sure that we do not get in this position again? Can the Minister indicate how we will make sure that the MHRA stays up to speed and is able to cope with new innovation in the future? I do not expect him to announce future fee increases now, but can he give us a sense of direction? In addition, what does the Department do to hold the MHRA to account? Does it scrutinise how quickly it works with industry and so on to deliver its services?
(1 year, 8 months ago)
Commons ChamberFor the first time in its 106-year history, the Royal College of Nursing has taken the monumental decision to take strike action. They have not taken that decision lightly, because no worker does, but this Government have pushed them to the brink. Ministers have had weeks to find a resolution, but they have rejected all offers of formal negotiations. As the RCN said, all meetings with the Government have seen Ministers sidestep the serious issues of NHS pay and patient safety. Do not be mistaken: they have the power and the responsibility to address this dispute, but they choose not to for self-serving political gains. They have seen that workers in rail, the Royal Mail, BT, universities and across the public and private sectors are now prepared to fight back because they are so sick of what this Government have been doing. They know full well that these disputes will have to end in pay rises for the workers of this country.
These are not the days of the miners’ strikes when the mines could just be closed because they were not needed any more. We are always going to need hospitals, we are always going to need railways, we are always going to need schools and we are always going to need universities. People are beginning to fight back and stand up, and it is time that the Government listened very carefully, especially in their so-called red wall seats.
At the height of the pandemic, every Thursday night the Prime Minister, the Health Secretary and Members across the House clapped for our NHS heroes and praised their immense effort on the frontline of the pandemic, but clapping does not pay a single bill. This dispute has highlighted the total hypocrisy at the heart of this Government. Once praised as heroes, nurses are now treated dreadfully. Ministers have sought to ratchet up the rhetoric, with the right hon. Member for Stratford-on-Avon (Nadhim Zahawi) seemingly seeking to present NHS workers as hostile agents of a foreign power, ludicrously and disgracefully dismissing industrial action as “helping Putin.” Get real! These are nurses, not agents of a foreign power. The Health Secretary has said that pay demands are “neither reasonable nor affordable”, while utterly refusing to engage with nurses’ unions over their demands, only offering a paltry 3% pay rise when inflation is well above 11%. According to The Times, instead of looking for a resolution to this dispute,
“Ministers plan to wait for public sentiment to turn against striking nurses as the toll of disruption mounts over the winter”.
The hon. Gentleman talked about the difference between the pay offer and inflation. If all public sector workers were given a pay rise in line with inflation, it would cost the equivalent of a 4.5p rise in the basic rate of income tax. Does he support that, or would he pay for such big pay rises in other ways?
(2 years, 4 months ago)
Commons ChamberI, too, congratulate my hon. Friend the Member for Gosport (Dame Caroline Dinenage) on securing this important debate. The level of attendance shows how important this issue is for MPs and for the country as a whole. According to the charity Children with Cancer UK, on average 12 children and young people are diagnosed with cancer every day. On 4 February 2014, nine-year-old Georgia Morris was one of them. I declare an interest because her parents, Richard and Selena, are friends, and Georgia went to my children’s school.
Georgia was diagnosed with neuroblastoma, a brain cancer that predominantly affects children. No one knows what causes neuroblastoma, or how to cure or treat it. Georgia got the best care possible from the NHS—her parents are keen to stress that—but it was care within the bounds of contemporary medical knowledge, which is severely limited. Since no one knows how to cure neuroblastoma, Georgia’s treatment was essentially a series of clinical trials of chemotherapy, radiotherapy and immunotherapy. She was given particular dosages to see whether they had any impact, and she showed extraordinary fortitude in the face of that. All those trials were funded by charity, with virtually no support from Government. According to Children with Cancer UK, of the 12 children and young people diagnosed with cancer every day, two will not survive. On 16 October 2016, aged 12, Georgia was one of them, dying at home with her family at her bedside. She would now be 18.
Georgia is far from unique. As we heard earlier, more children die from cancer than from any other sickness. When she was diagnosed, her parents were surprised to be told that there was no known treatment for neuro-blastoma, and little research into finding one. After she died they set up Georgia’s Fund, and have so far raised more than £200,000 for the charities Neuroblastoma UK and Children with Cancer UK. Working with the country’s top specialists, they are pushing research forwards. That is an amazing achievement, but it is also a drop in the ocean. I have many cancer research facilities in my constituency, which I visit, and I know that finding cures is painstakingly time consuming and expensive. Charities cannot do it on their own, and it is essential that Governments do more to support research into cancers that take lives so young.
As my hon. Friend the Member for Gosport (Dame Caroline Dinenage) said, we need a national mission for childhood cancer. It is certain that in time a cure for neuroblastoma will be found. It will be too late for Georgia, but not for other children. The more research we do now, the more young lives will be saved. We must do all we can to ensure that innocent children no longer have to go through what Georgia and her parents and family went through.
(3 years, 1 month ago)
Commons ChamberAnd volunteers and the police. The hon. Member for Rhondda (Chris Bryant) reminds us all of the role that policemen and women played in ensuring that the vaccination roll-out worked well. The very clear guideline is that we should take both personal and corporate responsibility. It is great to see Transport for London, other transport systems and the M10 of metro Mayors, which I speak to regularly, taking that corporate responsibility. We all have our part to play, as we have done by coming together and vaccinating the country at scale. This is the most infectious respiratory disease that is aerosol-transmitted.[Official Report, 21 July 2021, Vol. 699, c. 8MC.] We have to be very careful to ensure that we take this step carefully; for it to be irreversible, we have to continue to work together with a booster campaign. Beyond that, in the years to come, we have to get used to the transition from pandemic to endemic status.
As various hon. Members have noted, the number of coronavirus cases is rising very rapidly, but the great success of the vaccination scheme means that the number of deaths remains very low. That means that the fatality rate of coronavirus is now similar to that of other endemic viruses. Does my hon. Friend agree that with coronavirus now in approximately 200 countries around the world—almost every country in the world—the chance of eliminating it is almost zero, so as a society we have to learn to live with it, as we do with other serious infections such as flu and pneumonia?
I thank my hon. Friend for his excellent question; I agree. I remember that when I took on the role of vaccines Minister in November, I explained to the House and the country that the reason we began by vaccinating phase 1—the most vulnerable cohorts, as set out to us by the JCVI—was that categories 1 to 9 were where 99% of the virus’s mortality was coming from. That work has gone incredibly well: in all those categories we have uptake of more than 90%, in some of them it is at 95% or 96%, and in one it is even at 100%. There is very high uptake of the second dose as well. I think that it is right that we now take this step, pragmatically but cautiously, as we transition from pandemic to endemic status and help the rest of the world to do the same.
(3 years, 7 months ago)
Commons ChamberI join colleagues from across the House in welcoming the approval of the AstraZeneca vaccine. As I might have mentioned a couple of times, AstraZeneca has its global headquarters in my constituency. We often call it the Oxford vaccine, but I will call it the Oxford-Cambridge vaccine, for fairness.
I pay tribute to all the scientists, and to the Secretary of State for Health and Social Care, the Health Ministers and their team, for making sure that the UK has led the way in the fight against coronavirus. We are a world leader, not only in vaccination—we had the first approval, and now have the Oxford-Cambridge vaccine, which will be rolled out across the world—but in testing: we do more of it than any other European country. We are also world-leading in genomics. A colleague mentioned genomic surveillance. That is done largely in my constituency by the Wellcome Sanger Institute; we do more than the rest of the world put together. We are also world-leading in developing a clinically proven drug against coronavirus. The pandemic has shown that the UK is a life sciences superpower, and that is something of which we should be proud.
The new vaccine has been hailed as a game changer. When the announcement was made this morning, I could almost hear the sigh of relief across the country; finally, there was a light at the end of the tunnel. It was a great end to an absolutely horrible year, but as we have discussed this evening, the number of infections is rising as I speak. It is far higher than it has been, and so is the number of hospitalisations. NHS managers tell us that their hospitals are at the tipping point; they are creaking under the strain and may not be able to cope. That is why the Government announced new tier regulations just before Christmas and today. I support those regulations with a heavy heart, because I know the damage that they do to businesses, mental health and people’s lives, but having gone through all the data, I cannot see any alternative. I am very keen, though, for us to get out of them as quickly as possible. That, hopefully, is what the vaccine will allow us to do.
We now have a race between the infection rate, which is rising rapidly, and rolling out the vaccination as quickly as possible. The vaccination programme will change the dynamic of the pandemic, which means that we should change how we assess the restrictions and the tiers in future. At the moment, our focus is mainly on infection rates. That makes good sense, because infection leads to hospitalisation, and hospitalisation leads to death as night follows day; there is a clear link. As we vaccinate those most at risk—the elderly and the vulnerable—the death rate will come down rapidly. We could end up with infection rates staying quite high, particularly among unvaccinated young people, but death rates plummeting. There will be a breakdown in the relationship between the death rate and the infection rate, and that relationship has guided policy so far. The Government’s focus, in their policy on restrictions, should be not on infections, but on the death rate.
Let me give an example. Some 95% of deaths from coronavirus have been of people over the age of 60. Only 5% of deaths have been of people under that age. If we vaccinate all people over 60, which we can do by mid-February, it will lead to a 90% fall in the death rate, which is really quite astonishing. That is why, in recent months, I have been urging the Government to publish the case fatality rate—the proportion of people with coronavirus who end up dying. That rate has been plummeting. Our World in Data, an independent and highly respected website, does charts on countries around the world, and it says that the case fatality rate for coronavirus in the UK has dropped 75% since September. As the vaccine is rolled out, that rate will fall further and further.
One thing that we can all agree on in this House is that we do not want these restrictions longer than is absolutely necessary. I see at first hand in my constituency their impact on pubs, businesses, the events industry, wedding planners, and people’s social lives. We have to get out of the restrictions as quickly as possible. That is why I urge the Government, in the new year, to think not so much about the rate of infection as about the number of deaths. If deaths are going down, we can lift the restrictions.
I am 53 and in cohort 9—[Interruption.] Honestly! I know I do not look it. I have my own hair. In short, my point is: do not wait for people my age to get vaccinated before allowing the pubs of South Cambridgeshire to reopen. There is light at the end of the tunnel; let us make sure that we get there as quickly as possible.
(3 years, 9 months ago)
Commons ChamberI will try to be as brief as I can. I want to start by paying tribute to the people of South Cambridgeshire who have helped us all get through this pandemic—the care workers, the volunteers, the medical staff, the nurses and doctors, who have been working heroically, but also people from the private sector. I have found it very dismaying that the opposition parties have spent so long attacking the private sector. In my constituency, they have been developing the ventilators and doing genome decoding of coronavirus. They have developed the tests—a whole range of different tests—and they are producing the tests and delivering the tests for the Government. Most of the coronavirus tests are done in the private sector, not the public sector. They have developed rapid mass testing, but also the vaccine. We have heard a lot about this vaccine from Pfizer—and the whole country is hoping—but there is another vaccine from AstraZeneca, and its global headquarters are in South Cambridgeshire. We are all expecting results from that in a few weeks’ time, which will hopefully be as good as the Pfizer results. Again, that is a vaccine of which the Government in their wisdom, under Kate Bingham’s leadership, have bought a large stock.
In South Cambridgeshire, the balance that we have heard about from various Members—between lives and livelihoods, between lives and liberties—has been a particularly difficult decision. We have one of the lowest infection rates in the country, and we have had only one death from coronavirus in the last five months. A lot of companies have complained quite vociferously, and understandably, about the imposition of a national lockdown, but I have come to agree with the Government that it is actually needed, because cases have been taking off. We are now seeing that in South Cambridgeshire in recent days, and cases are now at a record level.
I want to make a few, very quick suggestions of what I think the Government could do or should think about doing to help reassure the public that they have got the right balance. One is that they could produce a cost-benefit analysis, with the quality-adjusted life years that they use in other areas; on the Treasury Committee, we have been looking at that. They could use the World Health Organisation definition of deaths, which is people who die from coronavirus, rather than with coronavirus, or if they have had it in the last 28 days. That is the standard international definition, and it is lower. They could provide an official estimate of the case fatality rate, which is the proportion of people who have the infection and die. That, by quite a few estimates, has dropped really quite sharply—by about two thirds—since the start. On 2 December, when the national lockdown ends, they could move to a more aggressive regional approach with a tier 4, which I know the Government are thinking about. With this, I think the Government will provide a lot more reassurance that they are getting the balance right, and it will help us get through this.
(3 years, 10 months ago)
Commons ChamberIn areas that we are already in discussions with, such as South Yorkshire, West Yorkshire, the north-east and Nottinghamshire, right across the board those discussions are constructive, positive and focused entirely on the wellbeing of people locally. I hope that in Hull cases stay relatively low and we do not have to go into a higher tier. There are no plans to do so at the moment, and I urge the people of Hull to keep following the rules and keep the coronavirus down in Hull. What I would say is that in every other part of the country, we have had highly constructive talks that have not involved this sort of party political point scoring. I urge that approach from everybody.
In my constituency, the latest figures show an infection rate of just 54 per 100,000—about half the national average and one tenth of the rate in Liverpool—so I think it is absolutely right that the Government are not following a national lockdown but are instead following a regional, local approach. In those areas that do need to go to tier 3, it is absolutely right that the Government give additional financial support, but it is also right, surely, that the Government treat them fairly and equally. The Government could not give greater support to one area, Greater Manchester, than to Liverpool or Lancashire, because then the local leaders who are refusing to take the action necessary to lock down the virus will be given greater financial rewards than the leaders who are taking the steps necessary.
This point about fairness is really important. Imagine how it would feel to be running a business or to be somebody who lives in Liverpool when there has been an agreement across party lines for the support that comes with the measures that are necessary, and then, after a very public disagreement, instead of the constructive work that we really hope to achieve, the result was a deal that was not proportionate and fair. Fairness is absolutely at the heart of what we are trying to achieve. That is why it is right that we have the extra offer of support that continues to be on the table. We want to strike a fair deal, but we have to take these measures to keep people safe.
(3 years, 11 months ago)
Commons ChamberI do not have those figures, but I would be very happy to look into specific cases, because the speed of turnaround in the instance that the hon. Gentleman describes is very important.
My right hon. Friend and his scientific advisers are absolutely right—the virus is not getting any weaker—but doctors, including many in my constituency of South Cambridgeshire, have made great progress in the treatment of coronavirus, and social distancing means that viral loads are less, making cases less severe for many people. Can he tell me what estimate he has made of the impact of these developments on the fatality rates for those who are affected?
Yes, of course. My hon. Friend represents one of the finest hospitals not just in the country but in the world. The clinicians who work at Addenbrooke’s and across the country have improved the treatment of coronavirus. We know that treatment with dexamethasone has reduced the death rate. We know that, because of earlier oxygenation and later intubation, that has reduced the death rate. There is also progress with remdesivir. Nevertheless, while that has reduced mortality for those going into hospital, the virus remains deadly, so unfortunately we have to take measures to stop its spread, not least because we can either take measures now or we will end up with a much bigger problem, still having to take measures later.
(3 years, 11 months ago)
Commons ChamberPhysiotherapy can play a key role in managing the symptoms of AS, and we should all support the work that physiotherapists do with patients.
I congratulate my hon. Friend on securing the debate on this important issue, and I pay tribute to his bravery in overcoming his condition and ensuring it did not prevent him coming to this House.
I have a family member, a friend and a constituent who suffer from AS, and I know well the problems with delayed diagnosis. My constituent Frances Reid started having symptoms 10 years ago. She went from doctor to doctor to doctor but did not get diagnosed. She was diagnosed only one year ago, and she now has pains across her entire body and needs joint replacements. She is in so much pain that she wakes up eight to 10 times a night. In contrast, a friend from Canada was diagnosed really early. With treatment and exercise, he leads a full life. What lessons can we learn from countries that have quicker diagnosis and what would my hon. Friend like to see here?
My hon. Friend neatly explains the consequences of delayed diagnosis. A recent systematic review of the available literature found that, overall, patients with a delayed diagnosis of AS had worse clinical outcomes, including higher disease activity, worse physical function and more structural damage compared with patients who had an earlier diagnosis. Those with a delayed diagnosis also had higher healthcare costs and a greater likelihood of work disability, as well as a worse quality of life, including a greater likelihood of depression. Those are the consequences of not giving a prompt diagnosis.
We spoke earlier about the National Axial Spondyloarthritis Society, or NASS, which has identified four factors that contribute to delay: a lack of awareness among the public that AS might be the cause of their chronic pain; GPs failing to recognise the features of AS; referral to non-rheumatologists who might not promptly recognise AS; and failure by rheumatology and radiology teams to optimally request or interpret investigations. AS cannot be cured, but reducing the eight-and-a-half-year average delay in diagnosis will lead to better outcomes for those living with the condition.
The all-party group for axial spondyloarthritis, of which I am a vice-chair, suggests three steps that would help to reduce the delay in diagnosis. The first is the adoption of a local inflammatory back pain pathway to support swift referral from primary care directly to rheumatology. Low levels of referral to rheumatology from primary care represent one of the key barriers to achieving an early diagnosis of AS, and a national audit by the APPG found that 79% of clinical commissioning groups do not have a specified inflammatory back pain pathway in place, despite NICE guidelines recommending that.
(3 years, 11 months ago)
General CommitteesAreas that are open to the public, where people are purchasing food, drink or refreshments, do not require the wearing of a mask. Again, I will clarify the wording to the right hon. Gentleman in writing, but that is the advice that I have been given. It beggars belief that anybody could consume food or drink while wearing a mask, but I will ensure that I clarify that information to him.
On reading this, I think it is very clear. If I dare say so, the right hon. Member for North Durham is misunderstanding what the Government policy is. Areas where there is food and drink in a transport hub are excluded from these regulations, so people do not have to wear a mask there them. I think it is really quite straightforward.
They are exempt.
The shadow Minister raised the issue of regulation 3(2)(c), which is intended to capture contractors working on site, medical practices, and those who are best placed to advise about their own medical practices—both people working in the medical practices and patients.
I would like to thank hon. Members. If there are any points that require a more detailed response, we will ensure—