Information between 15th March 2025 - 14th April 2025
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Written Answers |
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Breast Cancer: Research
Asked by: Julian Smith (Conservative - Skipton and Ripon) Friday 21st March 2025 Question to the Department of Health and Social Care: To ask the Secretary of State for Health and Social Care, if he will meet with the Lobular Moon Shot Project to discuss funding for lobular breast cancer research. Answered by Ashley Dalton - Parliamentary Under-Secretary (Department of Health and Social Care) The Department invests £1.6 billion each year on research through its research delivery arm, the National Institute for Health and Care Research (NIHR). NIHR research expenditure for all cancers was £133 million in 2023/24 reflecting its high priority. We are proud to have invested £29 million into the Institute of Cancer Research (ICR) and the Royal Marsden NIHR Biological Research Centre in 2022, supporting their efforts to strengthen research into cancer, including lobular breast cancer. Wider investments into breast cancer research include a £1.3 million project to determine whether an abbreviated form of breast magnetic resonance imaging can detect breast cancers missed by screening through mammography, including lobular breast cancer.
On 4 February 2025 the Department announced that almost 700,000 women across the country will take part in a world-leading trial to test how cutting-edge artificial intelligence (AI) tools can be used to catch breast cancer cases earlier. The Early Detection using Information Technology in Health (EDITH) trial is backed by £11 million of Government support via the NIHR.
The NIHR continues to encourage and welcome funding applications for research into any aspect of human health, including lobular breast cancer. Improving outcomes for people with cancer is a priority for the Government. |
Arms Length Bodies Publications |
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Apr. 14 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: R: Testicular function suppression (PDF 842 KB) (webpage) Published Found: Breast cancer research and treatment 151(1): 141-147 Giordano SH, Valero V, Buzdar AU et al. (2002) |
Apr. 14 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: T: Neoadjuvant chemotherapy for people with HER2 positive breast cancer (PDF 1.36 MB) (webpage) Published Found: Breast cancer research and treatment 205(2): 267-279 - Not a relevant study design Non-randomised |
Apr. 14 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: Q: Ovarian function suppression (PDF 5.32 MB) (webpage) Published Found: Translational breast cancer research : a journal focusing on translational research in breast cancer |
Apr. 14 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: S: Platinum based neoadjuvant chemotherapy (PDF 3.11 MB) (webpage) Published Found: Breast cancer research and treatment 145(2): 401-409 de Padua Souza, Cristiano, Carneiro, Ana Suellen |
Feb. 19 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: P: Non-pharmacological management of lymphoedema in people who have, or have had, breast cancer (PDF 3.28 MB) (webpage) Published Found: Breast cancer research and treatment 175(1): 191-201 Liu, Ying, Zhao, Xiaoyi, Song, Jian et al. (2023 |
Feb. 19 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: O: Non-pharmacological prevention of lymphoedema in people who have, or have had, breast cancer (PDF 1.42 MB) (webpage) Published Found: Wayne State University Study dates Not reported Sources of funding Department of Defense Breast Cancer Research |
Feb. 03 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Draft guidance consultation Document: Evidence review O (PDF 11.5 MB) (webpage) Published Found: Breast cancer research and treatment 145(2): 401-409 de Padua Souza, Cristiano, Carneiro, Ana Suellen |
Feb. 03 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Draft guidance consultation Document: Evidence review R (PDF 586 KB) (webpage) Published Found: Breast cancer research and treatment 151(1): 141-147 10 Zagouri, F, Sergentanis, T N, Koutoulidis, V |
Feb. 03 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Draft guidance consultation Document: Evidence review Q (PDF 18.98 MB) (webpage) Published Found: Breast cancer research and treatment 161(2): 185-190 - Systematic review used as source of primary |
Feb. 03 2025
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Draft guidance consultation Document: Evidence review P (PDF 3.65 MB) (webpage) Published Found: Breast cancer research and treatment 205(2): 267-279 - Not a relevant study design Non-randomised |
Sep. 09 2024
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Draft guidance consultation Document: Evidence review P (PDF 6.26 MB) (webpage) Published Found: Breast cancer research and treatment 184(2): 459-467 Kizil, Ramazan, Dilek, Banu, Sahin, Ebru et al |
Sep. 09 2024
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Draft guidance consultation Document: Evidence review O (PDF 849 KB) (webpage) Published Found: Wayne State University Study dates Not reported Sources of funding Department of Defense Breast Cancer Research |
Jan. 16 2024
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Update on 16 January 2024 Document: Health inequalities briefing (PDF 2.45 MB) (webpage) Published Found: multiple deprivation and ethnicity on breast screening uptake in the North West of England Breast Cancer Research |
Jan. 16 2024
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: N: Further surgery after breast-conserving surgery based on tissue margins (PDF 2.48 MB) (webpage) Published Found: Breast cancer research and treatment 189(2): 463- 470 Lupe, Krystine, Truong, Pauline T, Alexander, |
Nov. 16 2023
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Update on 16 January 2024 Document: Evidence review Evidence Review N (PDF 1.38 MB) (webpage) Published Found: Breast cancer research and treatment 189(2): 463-470 Lupe, Krystine, Truong, Pauline T, Alexander, Cheryl |
Jun. 14 2023
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: M: Effectiveness of different external beam hypofractionation radiotherapy regimens in people with early-stage or locally advanced invasive breast cancer (PDF 2.02 MB) (webpage) Published Found: Breast cancer research and treatment. 2013 Jan; 138:127–135. |
Apr. 05 2023
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: L: Strategies for reducing arm and shoulder problems after breast cancer surgery or radiotherapy (PDF 5.02 MB) (webpage) Published Found: Breast Cancer Research and Treatment 75(1): 35-50 Bruce, J., Mazuquin, B., Canaway, A. et al. (2021 |
Mar. 09 2023
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Update on 14 June 2023 Document: Evidence review (PDF 1.54 MB) (webpage) Published Found: BREAST CANCER RESEARCH AND TREATMENT 189(2): 387 - 398 Jain, N Sharma, R Sachdeva, K Kaur, A Sudan, |
Mar. 09 2023
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Update on 14 June 2023 Document: Health inequalities briefing (PDF 2.51 MB) (webpage) Published Found: for arm 43 lymphedema following breast cancer diagnosis in Black women and White women 44 Breast Cancer Research |
Feb. 03 2023
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Update on 05 April 2023 Document: Evidence review (PDF 3.04 MB) (webpage) Published Found: Breast Cancer Research and Treatment 75(1): 35-50 Bruce, J., Mazuquin, B., Canaway, A. et al. (2021 |
Feb. 03 2023
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Update on 05 April 2023 Document: Health inequalities briefing (PDF 2.42 MB) (webpage) Published Found: multiple deprivation and ethnicity on breast screening uptake in the North West of England Breast Cancer Research |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: J: Neoadjuvant treatment (PDF 2.82 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 58, 151-156. Danforth Jr 2003 Danforth Jr, D. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: F: Adjuvant biological therapy (PDF 1.43 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 158, 361-371. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: Supplement 1 - Health economics (PDF 393 KB) (webpage) Published Found: Breast Cancer Research & Treatment, 2014. 145(2): p. 267-79. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: K: Lifestyle (PDF 781 KB) (webpage) Published Found: 2002 and 2006 Source of funding This study was supported by the Department of Defense Breast Cancer Research |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: I: Postmastectomy radiotherapy (PDF 3.75 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 19, 77-84. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: H: Breast radiotherapy (PDF 2.23 MB) (webpage) Published Found: Breast Cancer Research & Treatment, 2013. 138(1): p. 127-35. Strnad 2016 Strnad, V., Ott, O. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Consultation comments and responses (PDF 1.72 MB) (webpage) Published Found: This should specifically include the signs and symptoms of secondary, or metastatic, breast cancer. Research |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Committee member list (PDF 664 KB) (webpage) Published Found: Christie NHS Foundation Trust 7.3.2016 Able to sign off expenditure (up to £2K) on a breast cancer research |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: E: Adjuvant chemotherapy (PDF 4.78 MB) (webpage) Published Found: Breast Cancer Research & Treatment, 128, 421-7. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: D: Endocrine therapy (PDF 2.2 MB) (webpage) Published Found: Breast Cancer Research & Treatment, 2014. 145(2): p. 267-79. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: B: Management of positive axilla (PDF 2.11 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 133, 667-676. Lu 2015 Lu, S. R., Hong, R. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: C: Adjuvant systemic therapy planning (PDF 1.21 MB) (webpage) Published Found: Breast Cancer Research, 19, 58. |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: A: Surgery to the breast (PDF 1.07 MB) (webpage) Published Found: after breast-conserving therapy: Analysis of 8485 patients treated over a 28-year period, Breast cancer research |
Jul. 18 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: G: Adjuvant bisphosphonates (PDF 2.45 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 125, 99-106. |
Feb. 26 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence Review A (PDF 1.69 MB) (webpage) Published Found: after breast -conserving therapy: Analysis of 8485 patients treated over a 28-year period, Breast cancer research |
Jan. 31 2018
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Supporting evidence Document: Appendix A: Summary of evidence from surveillance (PDF 857 KB) (webpage) Published Found: Breast Cancer Research & Treatment 138(3):961–5 49. |
Jan. 25 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence review G (PDF 4.49 MB) (webpage) Published Found: Breast Cancer Research 7 and Treatment, 125, 99-106. 8 Kristensen 2008 9 Kristensen, B., Ejlertsen |
Jan. 25 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence review E (PDF 8.87 MB) (webpage) Published Found: Breast Cancer Research & Treatment, 128, 421-7. 49 DRAFT FOR CONSULTATION Adjuvant chemotherapy |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report K (PDF 1.39 MB) (webpage) Published Found: Funding for supplemental projects was provided by the Breast Cancer Research Foundation and the |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Supporting documentation Health economics literature review (PDF 622 KB) (webpage) Published Found: Breast Cancer Research & Treatment, 2014. 145(2): p. 267-79. 6 Shah 2013 7 Shah, C., et al., Cost-efficacy |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report F (PDF 2.33 MB) (webpage) Published Found: Breast Cancer Research and 39 Treatment, 158, 361-371. 40 Vas-Luiz 2014 41 DRAFT FOR CONSULTATION |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report J (PDF 5.48 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 115, 101-113. 15 Wolmark 2001 16 Wolmark, N., Wang, J., Mamounas |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report I (PDF 7.03 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 19, 77-84. 27 NICE 2009 28 National Institute for Health and |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report H (PDF 4.57 MB) (webpage) Published Found: Breast Cancer Research & Treatment, 2013. 138(1): p. 127-35. 41 Strnad 2016 42 Strnad, V., Ott, O. |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report D (PDF 4.4 MB) (webpage) Published Found: [Erratum appears in Breast Cancer Res Treat. 2008 Nov;112(2):369], Breast Cancer Research & Treatment |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report B (PDF 4.3 MB) (webpage) Published Found: progressive resistance training in breast cancer: a systematic review and meta-analysis, Breast Cancer Research |
Jan. 24 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Evidence summary Evidence report C (PDF 2.48 MB) (webpage) Published Found: Breast Cancer Research, 19, 58. 12 Debray 2017 13 Debray, T., Damen, J., Snell, K., Ensor, J., Hooft |
Jan. 16 2018
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Original development on 18 July 2018 Document: Committee member list (PDF 653 KB) (webpage) Published Found: Christie NHS Foundation Trust 7.3.2016 Able to sign off expenditure (up to £2K) on a breast cancer research |
Oct. 20 2017
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Surveillance consultation Document: Surveillance review proposal (PDF 838 KB) (webpage) Published Found: Breast Cancer Research & Treatment 138(3):961–5 49. |
Aug. 16 2017
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Supporting evidence Document: Addendum (version 81.2) (PDF 4.82 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 90(1), 65-70. |
May. 11 2017
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Addendum consultation Document: Addendum (PDF 4.86 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 90(1), 65-70. |
Nov. 18 2015
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Supporting evidence Document: Surveillance review decision matrix - November 2015 (PDF 870 KB) (webpage) Published Found: Breast Cancer Research & Treatment 144:457-465. 29. |
Nov. 18 2015
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: Surveillance review decision matrix (NICE guideline CG80) - November 2015 (PDF 547 KB) (webpage) Published Found: Breast Cancer Research & Treatment 144:213-222. 37. |
Jun. 25 2015
NICE Source Page: Suspected cancer: recognition and referral Publication Type: Supporting evidence Document: Appendix J1 (PDF 6.1 MB) (webpage) Published Found: Improving Suspected Cancer: Appendix J1 (June 2015) Page 197 of 412 Outcomes in Breast Cancer. Research |
Jun. 25 2015
NICE Source Page: Suspected cancer: recognition and referral Publication Type: Supporting evidence Document: Appendix F (PDF 16.88 MB) (webpage) Published Found: Breast Cancer Research, 11: S10. Abstract only. |
Nov. 20 2014
NICE Source Page: Suspected cancer: recognition and referral Publication Type: Original development on 23 June 2015 Document: Appendices part 2 (PDF 8.19 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 144: 179-184. 36 Not in PICO 37 Ganz, P. A., Yip, C. |
Nov. 20 2014
NICE Source Page: Suspected cancer: recognition and referral Publication Type: Original development on 23 June 2015 Document: Appendices part 3 (PDF 8.31 MB) (webpage) Published Found: Breast Cancer Research and Treatment, 112: 359-361. 23 Not in PICO 24 Johnson, J. T., Newman, R. |
Jul. 01 2014
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Supporting evidence Document: Addendum (version 81.1) (PDF 1.82 MB) (webpage) Published Found: Breast Cancer Research & Treatment (2008 May ) 109;1 p9-26 Systematic review Cheema B;GaulCA. |
Mar. 11 2014
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Original development on 01 February 2009 Document: Advanced Breast Cancer: Addendum (PDF 1.6 MB) (webpage) Published Found: Breast Cancer Research & Treatment (2008 May ) 109;1 p9-26 Systematic review Cheema B;GaulCA. |
Feb. 13 2012
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Original development on 01 February 2009 Document: Breast cancer (advanced): consultation document (PDF 577 KB) (webpage) Published Found: Breast Cancer Research and Treatment 123:9-24. 9. |
Mar. 03 2009
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Supporting evidence Document: Full guideline (PDF 2.76 MB) (webpage) Published Found: Breast Cancer Research 9(3): R31. |
Mar. 03 2009
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Supporting evidence Document: Evidence review (PDF 3.87 MB) (webpage) Published Found: Breast Cancer Research & Treatment 100: 247-254. |
Mar. 03 2009
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Supporting evidence Document: Needs assessment (PDF 601 KB) (webpage) Published Found: California Breast Cancer Research Program. 6. |
Feb. 25 2009
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: Evidence review (PDF 10.61 MB) (webpage) Published Found: Breast Cancer Research 8[Suppl 1]. 2006. |
Feb. 25 2009
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Original development on 01 February 2009 Document: Breast cancer (advanced): stakeholder comments and developer responses (PDF 831 KB) (webpage) Published Found: individuals, regional groups and national organisations to campaign for improvements in breast cancer research |
Feb. 25 2009
NICE Source Page: Early and locally advanced breast cancer: diagnosis and management Publication Type: Supporting evidence Document: Full guideline (PDF 2.96 MB) (webpage) Published Found: Breast Cancer Research, 8 (Suppl 1): 19. |
Aug. 13 2008
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Original development on 01 February 2009 Document: Evidence review (PDF 2.86 MB) (webpage) Published Found: Breast Cancer Research & Treatment 100: 247-254. |
Aug. 13 2008
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Original development on 01 February 2009 Document: Full version (PDF 1.29 MB) (webpage) Published Found: Breast Cancer Research 9 (3). |
Aug. 13 2008
NICE Source Page: Advanced breast cancer: diagnosis and treatment Publication Type: Original development on 01 February 2009 Document: Needs assessment (PDF 364 KB) (webpage) Published Found: breast cancer in California: an inquiry into disparities and research needs: California Breast Cancer Research |