Question to the Home Office:

To ask His Majesty's Government, in regard to the Animals (Scientific Procedures) Act 1986: Non-technical summaries for project licences granted January – March 2025 that require a retrospective assessment, published on 11 June, what assessment they have made of the suffering caused to macaque monkeys.

Each application to use animals in science is subject to a robust and rigorous harm benefit assessment by a trained Home Office Inspector whom is a member of either the veterinary or medical profession. This ensures that any harm that may be caused to the animals is justified by the likely expected benefits for humans, animals or the environment.

All applications must conform with all legal requirements set out in the Animals (Scientific Procedures) Act 1986. This includes, applying the principles of the 3Rs (Replacement, Reduction and Refinement); the replacement of animals with alternatives, the reduction of the number of animals used to the minimum possible and the refinement of any techniques to reduce the harm suffered by the animals to the minimum. The Home Office conducts a robust and rigorous harm benefit assessment which requires a detailed justification of the harms and which demonstrates the 3Rs have been fully considered. All licence holders have a responsibility to fully implement the 3Rs throughout the lifetime of a licence and demonstrate this requirement at audit.

Licence holders are required to complete retrospective assessments for licences if the protocols in the studies are using non-human primates, cats, dogs and equidae and all those involving procedures classified as severe. Retrospective assessments must consider whether any lessons can be learnt from the programme of work which may contribute to the further implementation of the principles of replacement, reduction and refinement.

The Department for Science, Innovation & Technology (DSIT), the Home Office and DEFRA are engaging with stakeholders to finalise a strategy to accelerate the development, validation and uptake of alternatives to animal testing which is scheduled for publication later this year.