Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, if he will take steps to ensure that the National Genomic Test Directory for Cancer is expanded to include known biomarkers for rare forms of cancer.

The National Genomic Test Directory includes tests for over 7,000 rare diseases and over 200 cancer clinical indications, and includes both whole genome sequencing (WGS) and non-WGS testing. It is updated annually, following a robust and evidence-based process, with a fast-track scheme in place to make in-year changes. ​

The NHS Genomic Medicine Service has implemented next generation sequencing pan-cancer panels for solid tumours and haematological malignancies, including for rare cancers, as well as WGS for cancer patients. This has enabled testing for a larger number of genetic variations, the identification of known biomarkers to target treatment, and improved eligibility for clinical trials.

In April 2025, NHS England and National Institute for Health and Care Excellence (NICE) published a genomic testing pathway to support the rapid, safe adoption of innovation in genomics, including, for example, new testing for known biomarkers, into the National Health Service. Further information on the NICE genomic testing pathway is available at the following link:

https://www.england.nhs.uk/long-read/nhs-england-nice-genomic-testing-pathway/