Genetic Engineering

(asked on 20th October 2021) - View Source

Question to the Department of Health and Social Care:

To ask the Secretary of State for Health and Social Care, how many gene and cell therapies have been appraised by NICE through a Single Technology Appraisal; and what category of recommendation made in each of those cases was (a) recommended, (b) optimised, (c) Cancer Drugs Fund, (d) not recommended and (e) only in research.


Answered by
Edward Argar Portrait
Edward Argar
Minister of State (Ministry of Justice)
This question was answered on 28th October 2021

As of October 2021, the National Institute for Health and Care Excellence (NICE) has published technology appraisals guidance on seven gene and cell therapies. The following table shows NICE’s recommendation for each cell and gene therapy.

Technology

Categorisation

Talimogene laherparepvec

Optimised

Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells)

Optimised

Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells)

Only in Research

Autologous chondrocyte implantation using chondrosphere

Optimised

Tisagenlecleucel

Recommended (Cancer Drugs Fund)

Darvadstrocel

Not recommended

Axicabtagene ciloleucel

Recommended (Cancer Drugs Fund)

Tisagenlecleucel

Recommended (Cancer Drugs Fund)

Reticulating Splines