Question to the Department of Health and Social Care:
To ask the Secretary of State for Health and Social Care, how many gene and cell therapies have been appraised by NICE through a Single Technology Appraisal; and what category of recommendation made in each of those cases was (a) recommended, (b) optimised, (c) Cancer Drugs Fund, (d) not recommended and (e) only in research.
As of October 2021, the National Institute for Health and Care Excellence (NICE) has published technology appraisals guidance on seven gene and cell therapies. The following table shows NICE’s recommendation for each cell and gene therapy.
Technology |
| Categorisation |
|
Talimogene laherparepvec |
| Optimised |
|
Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) |
| Optimised |
|
Holoclar (ex vivo expanded autologous human corneal epithelial cells containing stem cells) |
| Only in Research |
|
Autologous chondrocyte implantation using chondrosphere |
| Optimised |
|
Tisagenlecleucel |
| Recommended (Cancer Drugs Fund) |
|
Darvadstrocel |
| Not recommended |
|
Axicabtagene ciloleucel |
| Recommended (Cancer Drugs Fund) |
|
Tisagenlecleucel |
| Recommended (Cancer Drugs Fund) |
|