(7 years, 5 months ago)
Commons ChamberI will come to that point, but I also want the Minister to hear this, because it is not the responsibility of his Department. It is crazy that it is not mandatory for all new school buildings to have sprinklers fitted. We must address that, as a matter of urgency. Again, I hope that, if the Minister is not given the advice that I certainly want him to be given, he will make a contrary decision and recommend that all new school buildings have sprinklers fitted.
I am grateful for what the hon. Gentleman has said about sprinkler systems in schools, but does he agree that it is also imperative for the regulations to be changed to cover student accommodation? I understand that tower blocks more than 30 metres high will now be fitted with sprinklers, but that student accommodation more than 30 metres high will not qualify. I hope my hon. Friend agrees that that cannot be right.
I certainly do agree. The Minister has heard what has been said. I understood that every building more than 30 metres high would have to have sprinklers fitted. I hope that at some stage when the Minister is winding up a note will be passed to determine whether or not the hon. Gentleman—he was at our meeting this morning— is right, but as far as I understand, that cannot be the position.
The APPG also agreed on the following:
“without prejudice to the public inquiry or the police criminal investigation, the all-party group…wish to support the recommendation of the coroners at Southwark and Southampton arising from the Lakanal House and Shirley Towers tower block”
—which was mentioned by the right hon. Member for Wentworth and Dearne (John Healey)—
“whereby both coroners recommended in a letter to the Secretary of State that the Department for Communities & Local Government, encourages providers of housing in high risk residential buildings containing multiple domestic premises to consider the retrofitting of sprinkler systems”.
I hope my hon. Friend the Minister will deal with that as well.
The APPG said:
“a letter to the then CLG Minister, dated 1st May 2014…drew the Minister’s attention to”
Ronnie King’s
“personal involvement with the Lakanal House Coroner’s Inquest, where clarification was given from the Department that the current Building Regulations allowed the composite panels under the external wall window sets of such tower blocks not to have any fire resistance”
—that is absolutely crazy—
“and that this weakness in the Regulations remains uncorrected today; despite the upward spread of fire which occurred, resulting in the deaths of six people.
(Under the current Building Regulations guidance Approved Document B, the external walls of Tower Blocks need only have a classification “O” Surface spread of Flame, with no fire resistance)”.
The House would not expect the Minister to be an expert on all these matters, and he will have to take advice from somewhere, but I hope he understands the frustration that has been caused by the ignoring of the APPG’s recommendations. This fire should never have happened, and it would not have happened if notice had been taken of our recommendations.
The Minister for Policing and the Fire Service —who is not in the Chamber at present—said:
“we are maybe looking at a system failure, built up over many years, which we now have to address urgently…over many years and perhaps against the backdrop of, as data shows, a reduced risk in terms of fire, in terms of number of incidents and deaths…maybe as a system some complacency has crept in.”
Well, it certainly has not “crept in” as far as the APPG is concerned.
(13 years ago)
Commons ChamberI congratulate the hon. Gentleman on bringing this issue before the House, and I very much support him. I am sure that he is going to come on to this point, but my response to the hon. Member for Strangford (Jim Shannon) would be that in an infamous case, thalidomide was proven safe for use on animals, but we all saw the tragic consequences of that. There has been a lot of publicity about that, but there are many other examples that have not had the same level of publicity. As the hon. Member for Southend West (Mr Amess) pointed out—before the hon. Member for Strangford came into the Chamber, I think—1 million people a year are hospitalised as a result of taking prescription medication. We must consider that problem, and I hope that the Minister will listen to the contribution of the hon. Member for Southend West this evening.
I welcome the support of the hon. Gentleman, whose maiden speech I was privileged to follow. I am going to mention two or three cases that enforce what he says.
There is ample evidence to support the fact that animal models do not function in their role. That is a very important matter for the Home Office to consider. In my time here many Ministers have held the relevant responsibility, and of course those advising Ministers are also very important. I do not expect the Minister to give me a firm yea or nay during the debate, but I hope she will write to me about the points that I make.
Experiments on animals cannot predict the mechanisms of the disease in question, risk factors or potential adverse reactions. According to the US Food and Drug Administration, the world’s largest drug regulator—I hate to keep using America as the example, but it seems to have the latest data—92% of potential new drugs fail in human trials. We cannot just dismiss that, because it is huge number, but no publicity is given to it. The drugs fail either because they do not work on, or are not safe for, humans. I will come later to one famous and disastrous incident. After appearing safe and effective in animal tests, those drugs fail completely.
Communities of senior scientists are very much aware of the dangers of using animals as human indicators. The Safer Medicines Trust, the patient safety charity of senior scientists, including Sir Ian Wilmut, the renowned “father” of Dolly the sheep, has expressed its concern. It is clearly not opposed to animal experimentation per se, but it is concerned for patients and for science in general. Indeed, it has sent open letters to the Prime Minister and the Secretary of State for Health stating that the current system for ensuring the safety of medicines before clinical trials is inadequate and results in harm to volunteers and patients.
These are difficult times, and I know that people are paid to volunteer for trials, but there have been a number of well-documented disastrous consequences. The danger to human beings from the use of animal testing is clear. Even in pre-clinical stages, lives have been lost because the results have misled scientists.
I wonder how many people realise that penicillin stayed on the shelf for more than a decade because the results in the rabbits on which Fleming tested it led him to believe that it would be ineffective in humans. That was quite the wrong outcome—and we can think of the number of lives that could have been saved all those years ago.
Lives are threatened in the human clinical stages of trials. In March 2006 six young men took part in a clinical trial at Northwick Park hospital and were nearly killed by a drug that had been tested on monkeys and shown to be safe, even at 500 times the dose that the men were given. That is not a trivial matter, and I can remember clearly when it happened. Again, I do not expect the Minister to respond now, but I hope that after she has taken advice she will be able to discuss what happened in that trial.
Clearly, the results from the monkeys created a false sense of security, yet the risk carries over even when drugs pass to market. Any number of hon. Members will have had constituents lobby them on the painkiller Vioxx, which was eventually withdrawn in 2004 after the biggest drug disaster in history—it killed more than 100,000 people worldwide in its five years on the market. Clinical trials of Vioxx revealed up to a fivefold increase in the risk of a serious reaction such as heart attack, heart failure or stroke, but tests on animals indicated that it was safe, and in some instances that it was protective to the heart, which supported the manufacturer’s decision to market the drug. I am currently dealing with two or three constituents whose loved ones were affected by the drug, and who are trying to get compensation, which, as hon. Members know, is quite a tough battle. One hundred thousand people were affected worldwide.
Why should animals be indicators of human response? Animals and humans are evolved complex systems and as such should be expected to demonstrate different responses to drugs and disease.