Written Parliamentary Question (Correction)

Anne Milton Excerpts

Wednesday 27th April 2011 Written Statements

[The Parliamentary Under-Secretary of State for Health (Anne Milton)]

In answering a parliamentary question from the hon. Member for Worthing West, (Sir Peter Bottomley), 1 March 2011, Official Report, column 379W, I provided details of the protection afforded by the two HPV vaccines licensed for use in the United Kingdom. These are Cervarix manufactured by GlaxoSmithKline and Gardasil manufactured by Sanofi Pasteur MSD.

However, my answer also referred to the cross-protection afforded by Cervarix, but I omitted to provide equivalent information on Gardasil and in doing so may have presented an incomplete view to the House.

In the case of Gardasil, the “Summary of Product Characteristics” states that

“statistically significant efficacy against disease was demonstrated against HPV types…related to HPV 16 (primarily HPV31) whereas no statistically significant efficacy was observed for HPV types ... related to HPV 18 (including HPV 45). For the 10 individual HPV types, statistical significance was only reached for HPV 31”.

To ensure clarity and completeness of information about the efficacy of both vaccines, I have placed copies of their “Summary of Product Characteristics” in the Library. Copies of the SPCs for Cervarix and for Gardasil are available for hon. Members from the Vote Office and for noble Lords from the Printed Paper Office. They can also be seen at:

www.medicines.org.uk/emc/medicine/20204/SPC/Cervarix/

www.medicines.org.uk/EMC/medicine/19016/SPC/GARDASIL/